Yazar "Çankaya, Murat" için listeleme
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Effect of hippophae rhamnoides extract on oxidative oropharyngeal mucosal damage induced in rats using methotrexate
Erhan, Ertuğrul; Terzi, Suat; Çeliker, Metin; Yaralı, Oğuzhan; Çankaya, Murat; Çimen, Ferda Keskin; Malkoç, İsmail; Süleyman, Bahadır (Korean Soc Otorhinolaryngol, 2017)Objectives. the objective of this study is to investigate and evaluate the effect of Hippophae rhamnoides extract (HRE) on oropharyngeal mucositis induced in rats with methotrexate (MTX) through biochemical, gene expression, ... -
Effect of thiamine pyrophosphate on oxidative damage to the oropharyngeal, nasal and cochlear tissues induced by doxorubicin in guinea pigs
Erhan, Ertuğrul; Turan, Fatih; Terzi, Suat; Çeliker, Metin; Mammadov, Renad; Malkoç, İsmail; Kukula, Osman; Çankaya, Murat (Colegio Farmaceuticos Provincia de Buenos Aires, 2017)Doxorubicin (DOX) inhibits the enzyme tyaminpyrophosphokinase (TPK). Hence the synthesis of thiamine pyrophosphate (TPP) which is the active metabolite of thiamine stops. This leads to oxidative damage. in the literature, ... -
Effects of nimesulide on oxidative mucosal injury induced by cisplatin in rat duodenum and jejunum
Özçiçek, Fatih; Çankaya, Murat; Çimen, Ferda K.; Kafa, Ayşe H. T.; Nalkıran, Hatice Sevim; Süleyman, Bahadır; Altuner, Durdu; Çetin, Nihal (Colegio Farmaceuticos Provincia de Buenos Aires, 2016)In this study, the impact of nimesulide on oxidative stress induced by cisplatin in rat duodenum and jejunum tissue was assessed by evaluating the biochemical and histopathological changes. the rats in the study were ... -
Liv-52; Prophylactic or therapeutic agent against desflurane-induced hepatotoxicity in rats
Kuyrukluyıldız, Ufuk; Binici, Orhan; Çetin, Nihal; Balcı, Mecdi Gürhan; Onk, Didem; Çankaya, Murat; Kafa, A. Hümeyra Taşkın; Altuner, Durdu; Yılmaz, Adnan (Colegio Farmaceuticos Provincia de Buenos Aires, 2016)Liv-52 has hepatoprotective effect and may be beneficial for desflurane hepatotoxicity. We aimed to investigate the prophylactic or therapeutic effects of Liv-52 on hepatotoxicity induced desflurane. the study was designed ... -
A novel therapeutics agent: antioxidant effects of hydroxylfasudil on rat kidney and liver tissues in a protamine sulphate-induced cystitis rat model; preliminary results
Bozkurt, Aliseydi; Budak, Harun; Erol, Hüseyin Serkan; Can, Serpil; Mercantepe, Tolga; Akın, Yiğit; Özbey, İsa; Çankaya, Murat; Halıcı, Mesut Bünyamin; Çoban, T. Abdülkadir (Taylor & Francis Ltd, 2018)Cystitis is defined as an inflammation of the bladder caused by a bacterial infection, and it can be dangerous and painful when it spreads through the internal organs. in this study, antioxidant effects of hydroxylfasudil ...