Yazar "Çiftel, Serpil" için listeleme
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Circadian clock on ionizing radiation-induced testicular injury
Çiftel, Serpil; Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Çiftel, Enver (AVES, 2024)Objective: This research focuses on the interaction between the circadian clock and the damage caused to testicular tissue by x-ray ionizing radiation. By examining the links between circadian rhythms and radiation -induced ... -
Comparative analysis of epigallocatechin-3-gallate and TNF-alpha inhibitors in mitigating cisplatin-induced pancreatic damage through oxidative stress and apoptosis pathways
Çiftel, Enver; Mercantepe, Filiz; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Çiftel, Serpil (Springer, 2024)Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as cancer cells. In this study, we aimed to investigate the effect of ... -
Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats
Çiftel, Serpil; Mercantepe, Filiz; Mercantepe, Tolga; Çiftel, Enver; Klisic, Aleksandra (Springer, 2024)Scalding burns are a common form of thermal injury that often leads to systemic complications. Pro-inflammatory cytokines like interleukin-6 (IL-6) and the activation of signal transducer and activator of transcription 3 ... -
The effect of anti-tumor necrosis factor therapy on the plasma atherogenic index in rheumatic diseases
Cüre, Osman; Kızılkaya, Bayram; Çiftel, Serpil; Mercantepe, Filiz (Mary Ann Liebert Inc., 2024)Background: The risk of atherosclerosis is increased in individuals with rheumatological disease. The objective of this study is to examine the heightened susceptibility to atherosclerosis in persons afflicted with ... -
Effect of fibromyalgia on demographic, biochemical, metabolic and inflammatory profiles: a single-centre retrospective study
Cüre, Osman; Kızılkaya, Bayram; Çiftel, Serpil; Klisic, Aleksandra; Çiftel, Enver; Mercantepe, Filiz (Pisa, Italy : Pacini editore, 2024)Objectives: The objective of this study is to ascertain the disparities in demographic features and biochemical profiles between individuals diagnosed with fibromyalgia (FM) and a control group of healthy individuals. Methods: ... -
The effects of dexmedetomidine on abdominal aortic occlusion-induced ovarian injury via oxidative stress and apoptosis
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Akyıldız, Kerimali; Çiftel, Serpil; Yılmaz, Adnan (Karger, 2023)Ischemia/reperfusion (IR) induced ovarian damage is caused by various diseases such as ovarian torsion, ovarian transplantation, cardiovascular surgery, sepsis, or intra-abdominal surgery. I/R-related oxidative damage can ... -
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
Çiftel, Serpil; Tümkaya, Levent; Saral, Sinan; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Mercantepe, Tolga (Springer, 2024)Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ... -
The importance of uric acid high-density lipoprotein cholesterol ratio as an indicator of visceral adiposity
Çiftel, Serpil; Mercantepe, Filiz (İnönü Üniversitesi Tıp Fakültesi, 2023)Aim: A number of anthropometric measurements are being developed to detect metabolic risks in overweight and obesity. Our purpose is to investigate the relationship of visceral adipocyte index (VAI), which is useful as a ... -
New approaches based on inflammatory indexes in the evaluation of the neoplastic potential of colon polyps
Çiftel, Sedat; Çiftel, Serpil; Klisic, Aleksandra; Mercantepe, Filiz (MDPI, 2024)Colorectal polyps, precursors to colorectal cancer (CRC), require precise identification for appropriate diagnosis and therapy. This study aims to investigate the differences in hematological and inflammatory markers, ... -
Radioprotective effects of alpha 2-adrenergic receptor agonist dexmedetomidine on X-ray irradiation-induced pancreatic islet cell damage
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Çiftel, Serpil; Çiftel, Sedat (Springer, 2023)Comprehensive epidemiological analyses conducted in the last 30 years have revealed a link between radiation and DM. We aimed to determine the effects of dexmedetomidine pretreatment on radiation-induced pancreatic islet ... -
Relationship between overnight dexamethasone suppression test and aging
Çiftel, Serpil; Mercantepe, Filiz (Cureus Inc., 2023)Background This study aims to investigate the relationship between suppressed cortisol levels measured after the 1-mg dexamethasone suppression test (DST) and age based on the hypothesis that aging can alter the activity ... -
Sex-specific associations between thyroid status, inflammation and hemostasis biomarkers in patients with subacute thyroiditis
Vekic, Jelena; Klisic, Aleksandra; Kotur-Stevuljevic, Jelena; Milinkovic, Neda; Gluscevic, Sanja; Çiftel, Serpil; Mercantepe, Filiz (MDPI, 2024)Background: Subacute thyroiditis (SAT) is characterized by profound inflammation and fluctuations in thyroid hormones which may affect the hemostasis balance. This study investigates sex-specific associations between thyroid ...
