Recep Tayyip Erdoğan Üniversitesi Kurumsal Akademik Arşivi
DSpace@RTEÜ, Recep Tayyip Erdoğan Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Metabolic dysfunction-associated steatotic liver disease in the MENA region: setting a research and action priority agenda
(John Wiley and Sons Inc, 2025) El-Kassas, Mohamed; Villota-Rivas, Marcela; Alswat, Khalid A.; AlNaamani, Khalid M.; Yılmaz, Yusuf; Labidi, Asma; Elzouki, Abdel-Naser
Background & Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing health challenge, particularly in Middle East and North Africa (MENA) countries. This study aimed to establish a consensus-driven research and action agenda to address MASLD within the MENA region. Methods: Following a global MASLD research and action agenda setting study, over two Delphi rounds (Rs), MENA region experts (R1 n = 112, R2 n = 104) indicated their level of agreement with and provided feedback on MASLD research and action priorities via Qualtrics XM. In R2, panellists also ranked the priorities, which were categorised across six domains: (1) the human and economic burden, (2) defining and implementing care models, (3) disease management, (4) education and awareness, (5) patient and community perspectives, and (6) leadership and policies for the MASLD public health agenda. Results: The consensus-built MASLD research and action priority agenda for the MENA region comprises 52 priorities. Combined agreement (i.e., ‘agree’ + ‘somewhat agree’) increased from 97.6% and 98.1% in R1 to 98.2% and 98.5% in R2 with the research (n = 30) and action (n = 22) priorities, respectively. The highest ranked research priorities included developing regional MASLD databases and validating non-invasive diagnostic tools. The highest ranked action priorities included taking steps to enhance the adoption of lifestyle interventions among people living with MASLD and improving disease knowledge among healthcare providers. Conclusions: This region-specific agenda can help to guide research and optimise clinical practice, thereby improving the understanding, prevention, and management of MASLD, enhancing health outcomes and reducing its burden within the MENA region.
Distinct characteristics of asthma overlap phenotypes: Insights from the Turkish adult asthma registry
(Taylor & Francis Group LLC Philadelphia, 2025) Kepil Özdemir, Seçil; Gemicioğlu, Bilun; Yıldız, Füsun; Hayme, Serhat; Alpagat, Gülistan; Karadoğan, Dilek; Çelik, Gülfem Elif
Introduct & imath;on: Considerable overlaps exist between asthma phenotypes and the clinical significance of these overlaps remains undetermined. The objective of this study is to analyze the characteristics of asthma overlap phenotypes using data from the Turkish Adult Asthma Registry (TAAR). Methods: This cross-sectional registry study included 2053 adult patients (74.8% female) with asthma. Results: Overall, 39.3% (n = 697) had allergic-eosinophilic (AE), 26.0% (n = 461) had allergic-non-eosinophilic (ANE), 21.3% (n = 377) had non-allergic-eosinophilic (NAE), and 13.4% (n = 237) had non-allergic-non-eosinophilic (NANE) asthma. Severe asthma exacerbations and emergency department (ED) visits were more frequent in the AE (28.3%, 31.2%, respectively) and NAE groups (36.0%, 34.0%, respectively) than in the ANE (14.3%, 20.6%, respectively) and NANE groups (12.6%, 16.7%, respectively) (p < 0.001). FEV1 values were significantly lower in the AE group than in the ANE and NANE groups (p < 0.001, p = 0.048, respectively) and in the NAE group than in the ANE group (p < 0.001). Risk factors for poor asthma control included living in rural areas, asthma-related ED visits, FEV1 < 60% in the NAE; being overweight, chronic rhinosinusitis, oral corticosteroids use, age < 40 years in the NANE; FEV1 < 80% in the AE; and severe asthma exacerbations, ED visits for AE and ANE groups. Conclus & imath;on: The considerable overlap between allergic and eosinophilic asthma phenotypes has clinical implications as increased rates of asthma exacerbations and healthcare utilization. The clinical heterogeneity among asthma phenotypes based on a single biomarker highlights the importance of multidimensional asthma phenotyping.
Cross-sectional analysis of health quality, treatment satisfaction and adherence in children with food allergy
(Marmara University, 2025) Günal, Özge; Sefer, Asena Pınar; Utuk, Burak; Altunbaş, Melek Yorgun; Güngöre, Ezgi Yalçın; Babayeva, Royala; Karakoc-Aydıner, Elif)
Objective: Food allergies (FA) significantly affect the quality of life (QoL) in children and their families. Management involves strict allergen avoidance, which can result in high emotional distress and an increased disease burden. Objective: To evaluate treatment adherence, satisfaction, and disease-specific health-related quality of life (HRQL) in children aged 0-12 years Methods: A cross-sectional study was conducted with 100 children diagnosed with FA by a physician who required allergen avoidance. Parents completed the Food Allergy Quality of Life Questionnaire Parent Form (FAQLQ-PF), Food Allergy Parent Questionnaire (FAPQ), Treatment Satisfaction Questionnaire (TSQM-9), and Modified Morisky Scale (MMS). Demographic and clinical data were obtained. Results: The median total score for FAQLQ-PF was 39 (IQR 26-54), indicating moderate impairment in QoL. Emotional impact and social/ dietary limitations were notably higher in children older than five years and those with multiple FA. The median FAPQ score was 38 (IQR 29-49), reflecting moderate parental stress and anxiety. Treatment satisfaction (TSQM-9) had a median score of 57 (IQR 41-71), with higher scores for parents of children with multisystem involvement. Treatment adherence (MMS) had a median score of 83 (IQR 67-100), indicating good overall adherence. Significant correlations were observed between higher parental anxiety and lower QoL. Conclusion: Children with FA and their parents experience significant HRQL impairment, stress, and varying levels of satisfaction with treatment. These results underscore the necessity for comprehensive management strategies that encompass psychosocial support and personalized interventions to enhance outcomes for families dealing with FA.
Design of online digital disaster training program for pre-service teachers
(2025) Seyihoğlu, Aydegül; Kartal, Ayça; Vekli, Güldah Sezen; Tekbıyık, Ahmet; Konur, Kader Birinci
At the basic education level, content related to disasters is included in the scope of courses such as Life Sciences, Science, and Social Studies. Studies reveal that teachers and pre-service teachers who conduct these courses are not equipped with the necessary technological and pedagogical skills. It is predicted that integrating disasters and disaster education, which have an interdisciplinary structure, with Web 2.0 technologies, one of today's digital learning tools, will make significant contributions to making disaster education effective. In this framework, the study aimed to design a "Digital Disaster Education Program" in an online learning environment for pre-service primary school, science and social sciences teachers. The study consists of three main parts: designing, implementing, and evaluating the Digital Disaster Education Program. Taba (Grassroots Rationale) model was used in the design of the program. The program, which had a five-day implementation period in the online environment, was repeated three times on different dates and with different participants within a year. In each implementation, 24 pre-service social studies, 24 pre-service science, and 24 pre-service primary school teachers (72 pre-service teachers in total) from across Turkey participated voluntarily. The digital disaster education materials developed by the participants during the program were evaluated with an analytical rubric. As a result, an example of Web 2.0 supported online disaster education programme based on Taba Model has emerged. After the evaluation process, some of the participant products were entitled to receive support by being projected toThe Scientific and Technological Research Council of T & uuml;rkiye (T & Uuml;B & Idot;TAK), which is one of the reflections of the positive results of the process. At the end of the study, suggestions were presented for the acquisition of disaster education and digital teaching skills in the pre-service process.
Dini ve manevi mücadele ölçeği’nin türkçe uyarlaması: geçerlik ve güvenirlik çalışması
(Atatürk University, 2025) Rehber, Dilanur; Vural, Muhammet Enes; Ekşi, Halil
This study aims to adapt the Religious and Spiritual Struggles Scale (RSS-14) developed by Exline, Pargament, Wilt, Grubbs and Yali in 2023 to Turkish through validity and reliability studies. This scale, which aims to measure the religious and spiritual struggle experienced by individuals, consists of 14 items and 6 subscales. The study group of the research group comprised 495 adults, including 302 women and 193 men. In the adapting process, after the first translation and pilot application, confirmatory factor analysis was applied to analyze the scale's factor structure. In the conclusion of the confirmatory factor analysis, the model demonstrated an acceptable level of fit. Accordingly, it is observed that the items constituting the scale have factor loadings ranging between .55 and .83. The overall internal reliability coefficient of the scale was found to be .82. Cronbach's alpha reliability coefficients regarding subscales range between .60 and .82. As a result of the item analysis, it has been observed that the discrimination level of the items in the scale was at a good level. The significant positive correlation between the Religious and Spiritual Struggles Scale and the negative religious coping sub-dimension of the Religious Coping Styles Scale showed that the criterion-related validity of the scale is at a sufficient level (r= .67; p<0.01). As a result of the study, it is affirmed that the Religious and Spiritual Struggles Scale is a valid and reliable measurement tool for Muslim Turkish culture.
