Yazar "Öztürk, Çiğdem" için listeleme
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Do immunohistochemical studies have a role in predicting prognosis of laryngeal squamous cell carcinomas? CD44 and fascin experience
Öztürk, Çiğdem; Paşaoğlu, Hüsniye Esra; Emre, Funda; Tetikkurt, Ümit Seza; Ege, Tülin Şentürk (Mattioli 1885, 2021)Background and objectives: The diagnosis of laryngeal squamous cell carcinoma (LSCC) can be made easily based on histopathological findings, but the relationship between morphological findings and prognosis is not clear. ... -
Does apoptotic index predict the response to neoadjuvant chemotherapy in patients with breast carcinoma?
Askan, Gökçe; Okcu, Oğuzhan; Öztürk, Çiğdem; Öztürk, Seda Duman; Şen, Bayram; Bedir, Recep (Galenos Publishing, 2023)Objective: Neoadjuvant chemotherapy (NACT) plays a major role in the treatment of patients with locally advanced breast carcinoma. Although most patients have benefited from NACT, the rate of residual tumors is still high ... -
An easy and practical prognostic parameter: tumor-stroma ratio in Luminal, Her2, and triple-negative breast cancers
Öztürk, Çiğdem; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (Assoc Medica Brasileira, 2022)OBJECTIVE: The stroma surrounding the tumor cells is important in tumor progression and treatment resistance, besides the properties of tumor cells. Studies on the tumor stroma characteristics will contribute to the knowledge ... -
Effect of tumor-infiltrating immune cells (mast cells, neutrophils and lymphocytes) on neoadjuvant chemotherapy response in breast carcinomas
Okcu, Oğuzhan; Öztürk, Çiğdem; Yalçın, Nazlıcan; Yalçın, Anıl Can; Şen, Bayram; Aydın, Esra; Öztürk, Ahmet Emin (Elsevier, 2024)Introduction: Despite screening, the incidence of breast cancer is increasing worldwide. Neoadjuvant chemotherapy (NAC) response is one of the most important parameters taken into consideration in surgery, optimal adjuvant ... -
Expression of cytotoxic T lymphocyte-associated antigen 4, CD44, and E-cadherin in the microenvironment of breast carcinomas
Savlı, Tuğçe Bölme; Paşaoğlu, Hüsniye Esra; Şavlı, Taha Cumhan; Muhammedoğlu, Ali; Tokoçin, Merve; Öztürk, Çiğdem (Associacao Medica Brasileira, 2023)OBJECTIVE: The expression of cytotoxic T lymphocyte-associated antigen 4, E-cadherin, and CD44 in the area of tumor budding was investigated in breast carcinomas in our study. METHODS: Tumor budding was counted at the ... -
GLUT-1 expression in breast cancer
Okcu, Oğuzhan; Şen, Bayram; Öztürk, Çiğdem; Güvendi, Gülname Fındık; Bedir, Recep (Federation of Turkish Pathology Societies, 2022)Objective: Numerous studies have been conducted to predict the prognosis of breast cancers. The effect of glucose transporter protein 1 (GLUT-1), the main carrier protein responsible for glucose transport, was investigated ... -
High tumor budding activity may predict poor prognosis in laryngeal squamous cell carcinomas
Öztürk, Çiğdem; Paşaoğlu, Hüsniye Esra; Emre, Funda; Ege, Tülin Şentürk; Tetikkurt, Ümit Seza (Wolters Kluwer Medknow Publications, 2022)Background: Laryngeal squamous cell carcinoma (SCC) which is the most common carcinoma of the respiratory system after lung carcinomas is graded by the World Health Organization (WHO) into three groups as grades 1, 2, and ... -
High tumor infiltrating lymphocytes are associated with overall survival and good prognostic parameters in endometrial endometrioid carcinoma patients
Öztürk, Çiğdem; Askan, Gökçe; Öztürk, Seda Duman; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (Federation Turkish Pathology Soc., 2023)Objective: The mortality incidence of endometrial carcinomas (ECs) has increased in recent years. Therefore, recent studies have focused on the cellular and microenvironmental properties of ECs. Tumor-infiltrating lymphocytes ... -
Histopathological findings in Turkish patients undergoing sleeve gastrectomy: is histopathologic examination of sleeve gastrectomy specimens clinically important?
Paşaoğlu, Hüsniye Esra; Özcan, Tevhide Bilgin; Öztürk, Çiğdem; Çelik, Elif; Şavlı, Tuğçe Bölme; Vartanoğlu, Talar (Springer, 2023)Purpose Sleeve gastrectomy (SG) is a widely used surgical method in the treatment of obesity. This study aimed to reveal the histopathological changes in SG materials and to investigate the prevalence of clinically important ... -
A lesion mimicking malignancy: Granulomatous orchitis
Öztürk, Çiğdem; Paşaoğlu, Esra; Şavlı, Tuğçe Bölme (Galenos Yayıncılık, 2021)Granulomatous orchitis is a rare disease with mixed chronic and granulomatous inflammation. Various factors cause granulomatous inflammation in the testicles, and it may accompany malignancies. Radiologically, granulomatous ... -
A new practical method of estimating tumoral microenvironment parameters of possible prognostic significance in patients with invasive breast carcinoma: Combined microenvironment score
Öztürk, Çiğdem; Okcu, Oğuzhan; Öztürk, Seda Duman; Askan, Gökçe; Şen, Bayram; Bedir, Recep (Elsevier, 2023)Background and objective: In recent years, the tumor microenvironment has become increasingly recognized as an influential factor in breast cancer development and growth. The parameters that form the microenvironment are ... -
Nucleolus assessment in invasive breast carcinoma, an objective parameter for histological grading
Öztürk, Seda Duman; Öztürk, Çiğdem; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (TUBİTAK Scientific & Technical Research Council Turkey, 2022)Background/aim: The nucleolus has the potential to provide insight into how many types of cancer will progress. In this study, we examined the evaluation of the nucleolus with a microscope in widespread breast cancer tumors ... -
Paraganglioma of the urinary bladder mimicking a urothelial carcinoma: a case report
Öztürk, Çiğdem; Güçer, Hasan; Çetinkaya Altuntaş, Seher; Okcu, Oğuzhan (Prusa Medical Publishing, 2023)Paragangliomas of the urinary bladder are rare tumors and can mimic urothelial carcinomas due to some features and can be misdiagnosed. A 71-year-old female was seen for hematuria and there was a solid lesion that measured ... -
Predicting response to neoadjuvant therapy with glucose transporter-1 in breast cancer
Öztürk, Seda Duman; Öztürk, Çiğdem; Okcu, Oğuzhan; Askan, Gökçe; Şen, Bayram; Bedir, Recep (Assoc Medica Brasileira, 2023)OBJECTIVE: Glucose transporter-1 is a marker involved in energy transport in cancer cells. It has been shown to be a poor prognostic factor in many cancer types, including breast cancer. However, there is no satisfactory ... -
Prognositc significance of microcystic elongated and fragmanted (MELF) myometrial ınvasion pattern: A retrospective study
Okcu, Oğuzhan; Askan, Gökçe; Şen, Bayram; Öztürk, Çiğdem; Öztürk, Seda Duman; Güvendi, Gülname Fındık (2022)Objective: Endometrioid endometrial carcinomas (EEC) are the most commonly diagnosed malignancies of the female genital tract. Myometrial invasion depth is one of the most significant pathological prognostic parameters. ... -
The prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast carcinomas
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Ayazoğlu, Muhammet Safa; Güvendi, Gülname Fındık; Öztürk, Seda Duman; Askan, Gökçe; Bedir, Recep (Elsevier, 2023)Background and objective: The prognostic importance of lymphoid cells in the tumor microenvironment and their effect on treatment response have been demonstrated in many cancer types. However, there are limited studies on ... -
Reporting hormone receptor expression in breast carcinomas: which method has the highest prognostic power and what should be the optimal cut-off value?
Öztürk, Çiğdem; Okcu, Oğuzhan; Öztürk, Seda Duman; Şen, Bayram; Öztürk, Ahmet Emin; Bedir, Recep (Sage Publications, 2024)Background . Hormone receptor (HR) expression is a critical marker that plays a role in the treatment and management of breast cancer. Even if patients receive hormone treatment with a hormone positivity rate of over 1%, ... -
Response to letter to the editor
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Ayazoğlu, Safa; Güvendi, Gülname Fındık; Öztürk, Seda Duman; Askan, Gökçe; Bedir, Recep (Elsevier, 2023)We would like to thank Dr. Altındağ for his interest in our publication (Prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast ... -
Surprise lesion in the cecum: benign multicystic peritoneal mesothelioma
Öztürk, Çiğdem; Gündoğdu, Hasan; Okcu, Oğuzhan; Bölme Şavlı, Tuğçe (Galenos Yayınevi, 2023)Benign multicystic peritoneal mesothelioma (BMPM) is a rare neoplasm that is difficult to distinguish from other cystic neoplasms radiologically. A 41-year-old female patient was admitted to the emergency service with a ... -
Tumor Budding is a reliable predictor for death and metastasis in invasive ductal breast cancer and correlates with other prognostic clinicopathological parameters
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Arpa, Medeni; Bedir, Recep (Elsevier, 2021)Background and objective: Breast cancers are the most common type of cancer and the most common cause of mortality in women worldwide. Different prognostic factors are the subject of research to differentiate the prognosis ...
