Yazar "İskender, Hatice" için listeleme
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The effect of hesperidin and quercetin on oxidative stress, NF-kappa B and SIRT1 levels in a STZ-induced experimental diabetes model
İskender, Hatice; Dokumacıoğlu, Eda; Şen, Tuğba Mazlum; İnce, İmran; Kanbay, Yalçın; Saral, Sinan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Objective: the aim of this study is to investigate the roles of SIRT1 and NF-kappa B in the pathogenesis of diabetes mellitus in rats with STZ-induced diabetes and determine the effects of hesperidin and quercetin on ... -
The effect of white tea on serum TNF-alpha/NF-kappa B and immunohistochemical parameters in cisplatin-related renal dysfunction in female rats
Saral, Sinan; Dokumacıoğlu, Eda; Mercantepe, Tolga; Atak, Mehtap; Çınar, Seda; Saral, Özlem; Yıldız, Lamiye; İskender, Hatice; Tümkaya, Levent (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)Objective: Nephrotoxicity is the most important side effect of the antineoplastic drug cisplatin, thereby restricting its use. the aim of this study was to investigate the protective effects of white tea infusions(WT) ... -
Effects of astaxanthin on biochemical and histopathological parameters related to oxidative stress on testes of rats on high fructose regime
Dokumacıoğlu, Eda; İskender, Hatice; Yenice, Güler; Kapakın, Kübra Asena Terim; Sevim, Çiğdem; Hayırlı, Armağan; Saral, Sinan; Çomaklı, Selim (Wiley, 2018)Astaxanthin (ASX) is a xanthophyll family of hydroxycarotenoids which contains several double bonds. It is produced by Haemococcus pluvialis, a microalgae and possesses antioxidant and anti-inflammatory properties. the aim ... -
The effects of hesperidin and quercetin on serum tumor necrosis factor-alpha and interleukin-6 levels in streptozotocin-induced diabetes model
Dokumacıoğlu, Eda; İskender, Hatice; Şen, Tuğba Mazlum; İnce,İmran; Dokumacıoğlu, Ali; Kanbay, Yalçın; Saral, Sinan (Medknow Publications & Media Pvt Ltd, 2018)Background: Diabetes mellitus (DM) is a metabolic disorder that occurs as a result of absolute or relative insufficiency of insulin release and/or insulin effect due to impairment of carbohydrate, fat and protein metabolism, ... -
Sülforafanın ratlarda asetaminofenin-indüklediği nefrotoksisitede sistatin-c düzeylerine etkisi
Dokumacioglu, Eda; İskender, Hatice; Aktaş, Mustafa Sinan; Hanedan, Başak; Dokumacıoglu, Ali; Şen, Tuğba Mazlum; Saral, Sinan (2016)Amaç: Canlıların kimyasallara ve ilaçlara maruziyeti sıklıkla karaciğer ve böbrek toksisitesi ile sonuçlanır. Toplum ve hastane kaynaklı böbrek hastalıklarının önemli ve büyük bir kısmını ilaçlar oluşturmaktadır. Çalışmamızda, ... -
White tea reduced bone loss by suppressing the TRAP/CTX pathway in ovariectomy-induced osteoporosis model rats
Yıldırım, Murat; Saral, Sinan; Mercantepe, Tolga; İskender, Hatice; Tümkaya, Levent; Atak, Mehtap; Taşçı, Filiz (S. Karger AG, 2020)Osteoporosis is an important skeletal disease characterized by bone weakness and high risk of fracture in postmenopausal women. Tea consumption is known to play an important role in the prevention or alleviation of ...