Yazar "Şen, Bayram" için listeleme
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Cellular immunity in individuals classified by antibody, after covid-19 infection/vaccine
Yılmaz, Niyazi Samet; Öztürk, Reyhan; Sen, Bayram; Ulukanlıgil, Mustafa (Türk Klinik Biyokimya Derneği, 2023)Aim: Regarding coronavirus disease (COVID-19), despite antibody measurement alone providing insufficient data, studies evaluating immune responses to vaccination or disease have focused on humoral immunity. Uncoupled humoral ... -
Contribution of the laboratory to a diagnosis process by sequential reflective testing: Paraprotein interference on a direct bilirubin assay
Yilmaz, Niyazi Samet; Şen, Bayram; Gülbahar, Özlem (Croatian Society of Medical Biochemistry and Laboratory Medicine, 2021)Errors in laboratory medicine occur in the preanalytical, analytical, and postanalytical phases. The errors are mostly detected in the preanalytical period. However, analytical errors are still an important source of error, ... -
Does apoptotic index predict the response to neoadjuvant chemotherapy in patients with breast carcinoma?
Askan, Gökçe; Okcu, Oğuzhan; Öztürk, Çiğdem; Öztürk, Seda Duman; Şen, Bayram; Bedir, Recep (Galenos Publishing, 2023)Objective: Neoadjuvant chemotherapy (NACT) plays a major role in the treatment of patients with locally advanced breast carcinoma. Although most patients have benefited from NACT, the rate of residual tumors is still high ... -
An easy and practical prognostic parameter: tumor-stroma ratio in Luminal, Her2, and triple-negative breast cancers
Öztürk, Çiğdem; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (Assoc Medica Brasileira, 2022)OBJECTIVE: The stroma surrounding the tumor cells is important in tumor progression and treatment resistance, besides the properties of tumor cells. Studies on the tumor stroma characteristics will contribute to the knowledge ... -
The effect of high serum lipid level on benign gallbladder diseases
Uyan, Mikail; Şen, Bayram; Arpa, Medeni; Okçu, Oğuzhan (Effect Publishing Agency ( EPA ), 2022)There is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of ... -
Effect of tumor-infiltrating immune cells (mast cells, neutrophils and lymphocytes) on neoadjuvant chemotherapy response in breast carcinomas
Okcu, Oğuzhan; Öztürk, Çiğdem; Yalçın, Nazlıcan; Yalçın, Anıl Can; Şen, Bayram; Aydın, Esra; Öztürk, Ahmet Emin (Elsevier, 2024)Introduction: Despite screening, the incidence of breast cancer is increasing worldwide. Neoadjuvant chemotherapy (NAC) response is one of the most important parameters taken into consideration in surgery, optimal adjuvant ... -
Evaluation of thiol-disulfide homeostasis in active ankylosing spondylitis patients
Arpa, Medeni; Şen, Bayram; Beyazal, Münevver Serdaroğlu; Erel, Özcan (Ediciones Doyma, S.L., 2021)Introduction and objectives: The etiopathogenesis of ankylosing spondylitis (AS), which is a chronic, progressive, inflammatory, systemic disease, has not been fully elucidated yet. Thiol-disulfide homeostasis, a component ... -
Factors affecting mortality in COVID-19 patients treated with tocilizumab
Cüre, Osman; İlkkılıç, Kadir; Şen, Bayram; Arpa, Medeni; Aydın, Esra; Avcı, Uğur; Tüfekçi, Damla; Polat, Hatice Beyazal; Kızılkaya, Bayram (Yuzuncu Yil Universitesi Tip Fakultesi, 2024)The aim of our study was to evaluate the risk factors associated with mortality in COVID-19 patients. During March 2020 to March 2022, 136 patients who were treated with tocilizumab in the service and intensive care unit ... -
FOBTs with lower detection limits increase the colonoscopy rates
Şen, Bayram; Okcu, Oğuzhan; Arpa, Medeni; Akdoğan, Remzi Adnan (Türk Klinik Biyokimya Derneği, 2023)Aim: Colon cancer, accounting for almost 10% of all cancers in both genders worldwide, is the fourth most common cause of cancer-related deaths. Approximately 95% of cases are originated from adenomas. In recent years, ... -
GLUT-1 expression in breast cancer
Okcu, Oğuzhan; Şen, Bayram; Öztürk, Çiğdem; Güvendi, Gülname Fındık; Bedir, Recep (Federation of Turkish Pathology Societies, 2022)Objective: Numerous studies have been conducted to predict the prognosis of breast cancers. The effect of glucose transporter protein 1 (GLUT-1), the main carrier protein responsible for glucose transport, was investigated ... -
High tumor infiltrating lymphocytes are associated with overall survival and good prognostic parameters in endometrial endometrioid carcinoma patients
Öztürk, Çiğdem; Askan, Gökçe; Öztürk, Seda Duman; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (Federation Turkish Pathology Soc., 2023)Objective: The mortality incidence of endometrial carcinomas (ECs) has increased in recent years. Therefore, recent studies have focused on the cellular and microenvironmental properties of ECs. Tumor-infiltrating lymphocytes ... -
A new practical method of estimating tumoral microenvironment parameters of possible prognostic significance in patients with invasive breast carcinoma: Combined microenvironment score
Öztürk, Çiğdem; Okcu, Oğuzhan; Öztürk, Seda Duman; Askan, Gökçe; Şen, Bayram; Bedir, Recep (Elsevier, 2023)Background and objective: In recent years, the tumor microenvironment has become increasingly recognized as an influential factor in breast cancer development and growth. The parameters that form the microenvironment are ... -
Nucleolus assessment in invasive breast carcinoma, an objective parameter for histological grading
Öztürk, Seda Duman; Öztürk, Çiğdem; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (TUBİTAK Scientific & Technical Research Council Turkey, 2022)Background/aim: The nucleolus has the potential to provide insight into how many types of cancer will progress. In this study, we examined the evaluation of the nucleolus with a microscope in widespread breast cancer tumors ... -
Predicting response to neoadjuvant therapy with glucose transporter-1 in breast cancer
Öztürk, Seda Duman; Öztürk, Çiğdem; Okcu, Oğuzhan; Askan, Gökçe; Şen, Bayram; Bedir, Recep (Assoc Medica Brasileira, 2023)OBJECTIVE: Glucose transporter-1 is a marker involved in energy transport in cancer cells. It has been shown to be a poor prognostic factor in many cancer types, including breast cancer. However, there is no satisfactory ... -
Prognositc significance of microcystic elongated and fragmanted (MELF) myometrial ınvasion pattern: A retrospective study
Okcu, Oğuzhan; Askan, Gökçe; Şen, Bayram; Öztürk, Çiğdem; Öztürk, Seda Duman; Güvendi, Gülname Fındık (2022)Objective: Endometrioid endometrial carcinomas (EEC) are the most commonly diagnosed malignancies of the female genital tract. Myometrial invasion depth is one of the most significant pathological prognostic parameters. ... -
The prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast carcinomas
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Ayazoğlu, Muhammet Safa; Güvendi, Gülname Fındık; Öztürk, Seda Duman; Askan, Gökçe; Bedir, Recep (Elsevier, 2023)Background and objective: The prognostic importance of lymphoid cells in the tumor microenvironment and their effect on treatment response have been demonstrated in many cancer types. However, there are limited studies on ... -
The relationship between SYNTAX II score and serum pleiotrophin level in patients with non-ST-segment elevation myocardial infarction
Nurkoç, Serdar Gökhan; Karayiğit, Orhan; Başyiğit, Funda; Şen, Bayram; Candemir, Mustafa (Galenos Publishing House, 2024)Background and Aim: In this study, we aimed to examine the relationship between serum pleiotrophin (PTH) levels at admission and the severity of coronary artery disease (CAD) in patients experiencing non-ST-segment elevation ... -
Reporting hormone receptor expression in breast carcinomas: which method has the highest prognostic power and what should be the optimal cut-off value?
Öztürk, Çiğdem; Okcu, Oğuzhan; Öztürk, Seda Duman; Şen, Bayram; Öztürk, Ahmet Emin; Bedir, Recep (Sage Publications, 2024)Background . Hormone receptor (HR) expression is a critical marker that plays a role in the treatment and management of breast cancer. Even if patients receive hormone treatment with a hormone positivity rate of over 1%, ... -
Response to letter to the editor
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Ayazoğlu, Safa; Güvendi, Gülname Fındık; Öztürk, Seda Duman; Askan, Gökçe; Bedir, Recep (Elsevier, 2023)We would like to thank Dr. Altındağ for his interest in our publication (Prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast ... -
The role of platelet to lymphocyte ratio (plr) in predicting early treatment response in diffuse large b cell lymphoma
İlkkılıç, Kadir; Şen, Bayram; Cüre, Osman (Springer, 2024)Background: Systemic inflammatory response in diffuse large B-cell lymphoma (DLBCL) is closely related to disease prognosis. Our aim is to determine the role of pretreatment platelet-to-lymphocyte ratio (PLR) in predicting ...