Yazar "Şener, Ebru" için listeleme
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Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Süleyman, Bahadır; Albayrak, Fatih; Akçay, Fatih (2012)Background: Oxidative liver injury occurring with methotrexate restricts its use in the desired dose. Therefore, whether or not thiamine and thiamine pyrophosphate, whose antioxidant activity is known, have protective ... -
Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation
Üçüncü, Yılmaz; Çelik, Nuray; Öztürk, Cengiz; Türkoğlu, Murat; Çetin, Nihal; Koçkara, Nizamettin; Şener, Ebru; Dündar, Cihat; Arslan, Aynur; Doğan, Hasan; Kurt, Nezahat; Süleyman, Halis (Pergamon-Elsevier Science Ltd, 2015)Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain ... -
A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ... -
Controlled reperfusion for different durations in the treatment of ischemia-reperfusion injury of the rat ovary: evaluation of biochemical features, molecular gene expression, and histopathology
Yapca, Ömer Erkan; Kumbasar, Serkan; Salman, Süleyman; Yaralı, Oğuzhan; Şener, Ebru; Mammadov, Renad; Tekin, Yeşim Bayoğlu; Aksoy, Ayşenur; Albayrak, Abdulmecit; Çetin, Nihal (Canadian Science Publishing, Nrc Research Press, 2015)High numbers of proinflammatory cells (PMNLs), which are carried by the blood to ischemic tissue during reperfusion, are considered responsible for inducing the inflammatory response that occurs in ischemia-reperfusion ... -
The effect of hippophae rhamnoides extract on oxidative damage on rat's gastric tissue depending on Co-implementation of methotrexate and indomethacin
Yılmaz, İsmayıl; Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Üçüncü, Yılmaz; Altuner, Durdu; Kurt, Nezahat; Kunak, Semih C.; Kısaoğlu, Abdullah; Özoğul, Bünyamin; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2014)The effect of Hippophae rhamnoides (HR) extract on oxidative damage on rat's gastric tissue depending on co-implementation of methotrexate (MTX) and indomethacin (IND) was investigated biochemically and histopathologically. ... -
The effect of nimesulide on oxidative damage inflicted by ischemia-reperfusion on the rat renal tissue
Süleyman, Zeynep; Şener, Ebru; Kurt, Nezahat; Çömez, Mehmet; Yapanoğlu, Turgut (Taylor & Francis Ltd, 2015)The objective of our study is to research biochemically and histopathologically the effect of nimesulide on oxidative damage inflicted by ischemia-reperfusion (I/R) on the rat renal tissue. Twenty-four albino Wistar type ... -
Examination of the effects of thiamine and thiamine pyrophosphate on doxorubicin-induced experimental cardiotoxicity
Polat, Bülent; Süleyman, Halis; Şener, Ebru; Akçay, Fatih (Sage Publications Inc, 2015)Background and Purpose: To investigate the effect of thiamine and thiamine pyrophosphate on doxorubicin-induced cardiotoxicity biochemically and histopathologically and to examine whether doxorubicin cardiotoxicity is ... -
Exogenous ATP administration prevents ischemia/reperfusion-induced oxidative stress and tissue injury by modulation of hypoxanthine metabolic pathway in rat ovary
Kumbasar, Serkan; Çetin, Nihal; Yapca, Ömer Erkan; Şener, Ebru; İsaoğlu, Ünal; Yılmaz, Mehmet; Salman, Süleyman; Aksoy, Ayşe Nur; Gül, Mehmet Ali; Süleyman, Halis (Univ Federal Santa Maria, 2014)In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were ... -
The impaired balances of oxidant/antioxidant and COX-1/COX-2 in ovarian ischemia-reperfusion injury and prevention by Nimesulide
İsaoğlu, Ünal; Yılmaz, Mehmet; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Bilen, Habib; Yapca, Ömer Erkan; Demiryılmaz, İsmail; İsaoğlu, Neslihan; Gül, Mehmet Ali; Kumbasar, Serkan; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2012)The aims of this study were to investigate the association of ovarian I/R injury with oxidant/antioxidant and cyclooxygenase activity and to examine the effect of nimesulide in I/R injury. Rats were divided into four groups: ... -
The investigation of damage in the muscle tissue with the oxidant/antioxidant balance and the extent of postmortem DNA damage in rats
Öztürk, Cengiz; Şener, Mustafa Talip; Şener, Ebru; Yılmaz, İsmail; Akçay, Fatih; Süleyman, Halis (2013)The relationship of the extent of DNA damage and certain components of the oxidant/antioxidant balance in rat femoral muscle tissue with the post-mortem intervals was investigated and examined by making direct comparison ... -
The prevention of ischemia/reperfusion induced oxidative damage by venous blood in rabbit kidneys monitored with biochemical, histopatological and immunohistochemical analysis
Çetin, Nihal; Süleyman, Halis; Şener, Ebru; Demirci, Elif; Gündoğdu, Cemal; Akçay, Fatih (Polish Physiological Soc, 2014)The purpose of this study was to investigate the biochemical, histopathological and immunohistochemical effects of venous blood on ischemia/reperfusion-induced oxidative DNA damage and mutation in rabbit kidneys in comparison ... -
Protective effect of mirtazapine against cisplatin-induced oxidative stress and DNA damage in guinea pig ear
Kuduban, Ozan; Kucur, Cüneyt; Üçüncü, Harun; Şener, Ebru; Süleyman, Halis; Akçay, Fatih (Scientific Publishers India, 2014)Cisplatin ototoxicity is a major dose-limiting factor in the treatment of several neoplastic diseases. Oxidative stress might play an important role of pathogenesis of cisplatin ototoxicity. the aim of this study was to ... -
The protective effect of thiamine pryophosphate against sugar-induced retinal neovascularisation in rats
Çinici, Emine; Mammadov, Renad; Fındık, Hüseyin; Süleyman, Bahadır; Çetin, Nihal; Çalık, İlknur; Balta, Hilal; Taş, İsmail Hakkı; Şener, Ebru; Altuner, Durdu (Verlag Hans Huber, 2018)The aim of this study was to investigate the effect of thiamine pyrophosphate (TPP), administered via sugar water, on retinal neovascularisation in rats. Animals were assigned to three groups, namely the TPP sugar-water ...
