Recep Tayyip Erdoğan Üniversitesi Kurumsal Akademik Arşivi
DSpace@RTEÜ, Recep Tayyip Erdoğan Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Cyberchondria and health anxiety in allergy and immunology
(Termedia Publishing, 2025) Evcen, Recep; Çölkesen, Fatih; Yıldız, Eray; Aykan, Filiz Sadi; Kılınç, Mehmet; Önalan, Tuğba; Arslan, Şevket
Introduction: The widespread use of the internet has made health information more accessible. However, it has also increased problems such as health anxiety and cyberchondria. Aim: This study aimed to assess cyberchondria levels in allergy and immunology clinic patients and examine the relationship between cyberchondria and health anxiety. Material and methods: This study was conducted on patients diagnosed with allergic disorders, chronic urticaria, hereditary angioedema (HAE), and primary immunodeficiency (PID). Cyberchondria severity was assessed using the Cyberchondria Severity Scale (CSS-12), while health anxiety was evaluated using the Short Health Anxiety Inventory (SHAI). Results: A total of 550 patients were included in the study, with 71% of the participants being female. The highest CSS-12 scores were observed in the HAE group (33.5 +/- 8.8), followed by the PID group (28.4 +/- 8.6). The allergic disorders group had the lowest level of cyberchondria severity (27.7 +/- 8.5). According to SHAI scores, PID and HAE groups had the highest values. A significant positive relationship was found between cyberchondria and health anxiety (r(548) = 0.416, p < 0.001). Conclusions: An increase in cyberchondria raises health anxiety and disease burden among allergy and immunology patients. Therefore, physicians should take this into account when treating these patients.
Mathematics teacher educators’ instructional modifications: A cultural-comparative study using a Czech mathematics classroom video
(Springer Nature, 2025) Okumuş, Samet; Vondrová, Naďa
In this cultural-comparative study, we examined the recommendations for instructional modifications made by 12 Czech and 12 non-Czech mathematics teacher educators (MTEs). The non-Czech MTEs were selected from countries culturally distinct from Czechia, including Costa Rica, Japan, Kosovo, Türkiye, the UK, and the USA, with two MTEs from each country. The participants were invited to provide written feedback on a part of a video lesson (teaching segment) in which a Czech elementary mathematics teacher handled student errors. The results demonstrated that the Czech MTEs emphasized individual learning and content, while the non-Czech MTEs’ feedback was more diverse, advocating a more collaborative and reflective learning environment. Drawing on the limitations of our study, implications for future research are provided.
Predicting excellent response to radioiodine in differentiated thyroid cancer using machine learning
(Pacini Editore Srl, 2025) Bülbül, Ogün; Nak, Demet
Objective. If excellent response (ER) occurs after radioactive iodine (RAI) treatment in patients with differentiated thyroid carcinoma (DTC), the recurrence rate is low. Our study aims to predict ER at 6-24 months after RAI by using machine learning (ML) methods in which clinicopathological parameters are included in patients with DTC without distant metastasis. Methods. Treatment response of 151 patients with DTC without distant metastasis and who received RAI treatment was determined (ER/nonER). Thyroidectomy ± neck dissection pathology data, laboratory, and imaging findings before and after RAI treatment were introduced to ML models. Results. After RAI treatment, 118 patients had ER and 33 had nonER. Before RAI treatment, TgAb was positive in 29% of patients with ER and 55% of patients with nonER (p = 0.007). Eight of the ML models predicted ER with high area under the ROC curve (AUC) values (> 0.700). The model with the highest AUC value was extreme gradient boosting (AUC = 0.871), the highest accuracy shown by gradient boosting (81%). Conclusions. ML models may be used to predict ER in patients with DTC without distant metastasis.
Investigating the role of teaching sports and physical activity in leisure time and the quality of work life of selected hospital personnel in Turkiye
(Centro University, 2025) Üstün, Neslişah Aktaş; Güler, Yunus Emre
The purpose of this research was to investigate the relationship between teaching sports in leisure time and the quality of work life in the personnel of selected hospitals in Turkiye. Its statistical population consists of employees of selected hospitals Medical Park Bahcelievler, Acibadem Bakirkoy, Liv Hospitals Ulus Liv Hospital Bahcesehir, Aji Badem International Hospital, of which 360 people were selected as a statistical sample. To collect data for analysis, Sharkley's physical activity questionnaire and Walton's quality of work life questionnaire (1974) were used. The face and content validity of the research tool was approved by sports experts. Also, the reliability of the entire measurement tool was investigated in a preliminary study and Cronbach's alpha coefficient was calculated for the quality of work life variable (0.947) and for the physical activity variable (0.876). All statistical analyzes were performed using SPSS version 24 software. The results showed that there is a positive and significant relationship between teaching sports and physical activity in leisure time and the quality of work life and its components. In general, according to the results of the research, it is suggested to pay serious attention to teaching sports and physical activity, which has been effective on the variables of the quality of work life, in order to have committed and healthy employees.
Radioprotective effects of coenzyme Q10 on X-ray radiation-induced intestinal damage via oxidative stress and apoptosis
(Elsevier, 2025) Uyan, Mikail; Yılmaz, Hamit; Tümkaya, Levent; Suzan, Zehra Topal; Mercantepe, Tolga
Aim: The World Health Organization reported that cancer was the cause of death for 9.7 million people in 2022, and the numbers continue to rise every day. The present study examines the potential radioprotective effects of ubiquinone against x-ray radiation-induced intestinal damage and offers insight into new near-future methods for the treatment of radiation-induced tissue toxicity. Materials and Methods: Thirty-two male Sprague-Dawley rats were randomly divided into four groups. Group I (control) received no treatment during the experiment; Group II (IR [a single dose of 2 Gy pelvic/abdominal ionizing radiation]) received radiation only; Group III (a low dose of CoQ10 [30 mg/kg CoQ10 by oral gavage for 7 d] + IR) and Group IV (a high dose of CoQ10 [150 mg/kg CoQ10 by oral gavage for 7 d] + IR). The rats were sacrificed 24 h after x-ray radiation, and tissues were collected from the small intestine and subjected to histochemical analysis. Results: Diffuse villous fusion, enterocyte loss, hemorrhagic areas, inflammation, and fibrosis were observed in the IR group, as well as an increase in apoptotic enterocytes. In contrast, a decrease was observed in the IR+LD-CoQ10 and IR+HD-CoQ10 groups, along with a decrease, especially in villous fusion and enterocyte loss, hemorrhagic areas, inflammation, and fibrosis. Conclusion: CoQ10 was found to reduce duodenal damage, oxidative stress, and apoptosis induced by x-ray radiation exposure and had a radioprotective effect.
