Yazar "Boz Er, Asiye Büşra" için listeleme
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Integrin β3 reprogramming stemness in HER2-positive breast cancer cell lines
Boz Er, Asiye Büşra (MDPI, 2024)HER2-positive breast cancer, characterised by overexpressed HER2 levels, is associated with aggressive tumour behaviour and poor prognosis. Trastuzumab is a standard treatment; however, approximately 50% of patients develop ... -
PAI1 regulates cell morphology and migration markers in trastuzumab-resistant HER2-positive breast cancer cells
Boz Er, Asiye Büşra; Er, İdris (Multidisciplinary Digital Publishing Institute (MDPI), 2024)HER2-positive breast cancer is a significant cause of mortality. Overcoming trastuzumab resistance requires a deeper understanding of its molecular mechanisms to develop effective therapies. This study investigates the ... -
Targeting ITGβ3 to overcome trastuzumab resistance through epithelial–mesenchymal transition regulation in HER2-positive breast cancer
Boz Er, Asiye Büşra; Er, İdris (MDPI, 2024)HER2-positive breast cancer, representing 15–20% of all breast cancer cases, often develops resistance to the HER2-targeted therapy trastuzumab. Unfortunately, effective treatments for advanced HER2-positive breast cancer ...
