Yazar "Chen, Li" için listeleme
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Aramchol improves hepatic fibrosis in MASH: Results of multimodality assessment using both conventional and digital pathology
Ratziu, Vlad; Yılmaz, Yusuf; Lazas, Don; Friedman, Scott L.; Lackner, Caroline; Behling, Cynthia; Cummings, Oscar W.; Chen, Li; Petitjean, Matthieu; Gilgun-Sherki, Yossi; Gorfine, Tali; Kadosh, Shaul; Eyal, Eli; Sanyal, Arun J. (Wolters Kluwer Medknow Publications, 2024)Background and aims: Antifibrotic trials rely on conventional pathology (CP) despite recognized limitations. We compared single fiber digital image analysis (DIA) with CP to quantify the antifibrotic effect of Aramchol, a ... -
Hepatocyte apoptosis fragment product cytokeratin-18 M30 level and non-alcoholic steatohepatitis risk diagnosis: an international registry study
Zhang, Huai; Rios, Rafael S.; Boursier, Jerome; Anty, Rodolphe; Chan, Wah-Kheong; George, Jacob; Yılmaz, Yusuf; Wong, Vincent Wai-Sun; Fan, Jiangao; Dufour, Jean-Francois; Papatheodoridis, George; Chen, Li; Schattenberg, Joern M; Shi, Junping; Xu, Liang; Wong, Grace Lai-Hung; Lange, Naomi F.; Papatheodoridi, Margarita; Mi, Yuqiang; Zhou, Yujie; Byrne, Christopher D.; Targher, Giovanni; Feng, Gong; Zheng, Minghua (Lippincott Williams & Wilkins, 2023)Background:Liver biopsy for the diagnosis of non-alcoholic steatohepatitis (NASH) is limited by its inherent invasiveness and possible sampling errors. Some studies have shown that cytokeratin-18 (CK-18) concentrations may ... -
Tropifexor plus cenicriviroc combination versus monotherapy in nonalcoholic steatohepatitis: Results from the phase 2b TANDEM study
Anstee, Quentin M.; Lucas, Kathryn J.; Francque, Sven; Abdelmalek, Manal F.; Sanyal, Arun J.; Ratziu, Vlad; Gadano, Adrian C.; Rinella, Mary; Charlton, Michael; Loomba, Rohit; Mena, Edward; Schattenberg, Jörn M.; Noureddin, Mazen; Lazas, Donald; Goh, George B.B.; Sarin, Shiv K.; Yılmaz, Yusuf; Martic, Miljen; Stringer, Rowan; Kochuparampil, Jossy; Chen, Li; Rodriguez-Araujo, Gerardo; Chng, Elaine; Naoumov, Nikolai V.; Brass, Clifford; Pedrosa, Marcos C. (Wolters Kluwer Medknow Publications, 2023)Background and Aims: With distinct mechanisms of action, the combination of tropifexor (TXR) and cenicriviroc (CVC) may provide an effective treatment for NASH. This randomized, multicenter, double-blind, phase 2b study ...
