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Usnic acid suppresses inflammation and endoplasmic reticulum stress in a methotrexate-induced pulmonary toxicity model via modulating Nrf2 pathway

Demir, Selim; Alemdar, Nihal Türkmen; Yuluğ, Esin; Demir, Elif Ayazoğlu; Durmuş, Tenzile Beyza; Menteşe, Ahmet; Aliyazıcıoğlu, Yüksel (Elsevier, 2025)

Pulmonary toxicity represents a significant adverse effect of methotrexate (MTX), characterised by increased oxidative stress (OS) and inflammation. This study focused on revealing the therapeutic role of usnic acid (UA) ...