Yazar "Gülüm, Levent" için listeleme
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HSP inhibitor sensitize resistant MCF-7 cells to doxorubicin through suppressing HSP90AB4P pseudogene and HSPB1 expression
Coşkun, Kübra Açıkalın; Tutar, Lütfi; Abay, Elif Cansu; Gülüm, Levent; Çelik, Ayşe Büşranur; Gümüş, Mehmet; Koca, İrfan; Tutar, Yusuf (Bentham Science Publishers, 2025)Introduction: Doxorubicin, a first-line chemotherapeutic agent, often faces resistance in breast cancer subtypes, leading to treatment failure. HSPs (Heat shock proteins), especially HSP90, and their pseudogenes like ... -
In vitro effects of rumex confertus extracts on cell viability and molecular pathways in MCF-7 breast cancer cells
Gülüm, Levent; Güler, Emrah; Aktaş, Fatma Lale; Çelik, Ayşe Büşranur; Yılmaz, Hilal; Tutar, Yusuf (MDPI, 2025)Rumex confertus (RC), a plant known for its traditional medicinal uses, has shown potential anticancer properties, particularly due to its rich phenolic content. Despite its promising bioactivity, its effects on breast ... -
Phytochemical profiling and anticancer potential of pistachio wastes against MCF-7 breast cancer cells: a metabolic and apoptotic pathway analysis
Gülüm, Levent; Güler, Emrah; Zırhlı, Çağla Başak; Çelik, Ayşe Büşranur; Tutar, Yusuf (BioMed Central Ltd, 2025)Food waste poses significant environmental, economic, and social challenges worldwide. Pistachio waste is recognized for its health benefits, particularly for its anticancer properties. This study assessed the phytochemical ... -
Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents
Çapan, İrfan; Hawash, Mohammed; Qaoud, Mohammed T.; Gülüm, Levent; Tunoğlu, Ezgi Nurdan Yenilmez; Çifci, Kezban Uçar; Çevrimli, Bekir Sıtkı; Sert, Yusuf; Servi, Süleyma; Koca, İrfan; Tutar, Yusuf (BioMed Central Ltd., 2024)Background: Carbazole-based molecules containing thiosemicarbazide functional groups are recognized for their diverse biological activities, particularly in enhancing therapeutic anticancer effects through inhibiting crucial ... -
Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents (vol 18, 102, 2024)
Çapan, İrfan; Hawash, Mohammed; Qaoud, Mohammed T.; Gülüm, Levent; Tunoğlu, Ezgi Nurdan Yenilmez; Çifci, Kezban Uçar; Çevrimli, Bekir Sıtkı; Sert, Yusuf; Servi, Süleyman; Koca, İrfan; Tutar, Yusuf (BMC, 2024)........
