Recep Tayyip Erdoğan Üniversitesi Kurumsal Akademik Arşivi
DSpace@RTEÜ, Recep Tayyip Erdoğan Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region
(Frontiers Media SA, 2025) El-Kassas, Mohamed; Khalifa, Rofida; Medhat, Mohammed A.; Yılmaz, Yusuf; Tumi, Ali; Labidi, Asma; AlNaamani, Khalid M.
Background: Artificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain. We assessed awareness, use, perceived value, barriers, and policy priorities among hepatology clinicians in the region. Methods: A cross-sectional online survey targeted hepatologists and gastroenterologists across 17 MENA countries. The survey assessed clinical and research applications of AI, perceived benefits, clinical and research use, barriers, ethical considerations, and institutional readiness. Descriptive statistics and thematic analysis were performed. Results: Of 285 invited professionals, 236 completed the survey (response rate: 82.8%). While 73.2% recognized the transformative potential of AI, only 14.4% used AI tools daily, primarily for imaging analysis and disease prediction. AI tools were used in research by 39.8% of respondents, mainly for data analysis, manuscript writing assistance, and predictive modeling. Major barriers included inadequate training (60.6%), limited AI tool access (53%), and insufficient infrastructure (53%). Ethical concerns focused on data privacy, diagnostic accuracy, and over-reliance on automation. Despite these challenges, 70.3% expressed strong interest in AI training., and 43.6% anticipating routine clinical integration within 1–3 years. Conclusion: MENA hepatologists are optimistic about AI but report limited routine use and substantial readiness gaps. Priorities include scalable training, interoperable infrastructure and standards, clear governance with human-in-the-loop safeguards, and region-specific validation to enable safe, equitable implementation.
Biofuel research and development technologies: a Load Capacity Curve analysis for European sustainable development
(Taylor and Francis Ltd., 2025) Pata, Uğur Korkut; Karlıer Pata, Selin
In the face of accelerating climate change and resource depletion, the sustainability of biofuels has become an important research focus in environmental economics. While previous studies have extensively examined the role of biofuel consumption in reducing CO₂ emissions, the environmental effectiveness of biofuel-specific investments in research and development (R&D) remains largely unexplored. This study fills this gap by empirically assessing the impact of biofuel-related R&D expenditures on the Load Capacity Factor (LCF). Using annual panel data for ten European countries over the period 2009–2023, the analysis rigorously tests the Load Capacity Curve (LCC) hypothesis, which postulates a non-linear, U-shaped relationship between economic growth and ecological balance. The study makes a novel theoretical contribution by integrating biofuel innovations into the LCC framework. Three second-generation panel estimators are used to ensure robust conclusions in the presence of cross-sectional dependence (CSD). The results consistently confirm the LCC hypothesis and reveal that biofuel R&D expenditures have a positive effect on LCF improvement. Furthermore, the estimated turning points indicate heterogeneous ecological transitions across countries, emphasizing the role of income levels and technological capacity in shaping sustainability pathways. By linking the biofuel innovation literature to the LCC framework, this study provides new insights for policymakers seeking to align renewable energy development and technological innovation with the Sustainable Development Goal 7 (SDG-7) targets. The findings highlight the necessity of targeted biofuel R&D strategies to enhance biocapacity, reduce ecological pressure, and guide European economies towards a more resilient and sustainable future.
Treasure lying beneath the waters: exploring the deep connections between biodiversity and the blue economy
(Frontiers Media SA, 2025) Çamkaya, Serhat; Kaya, Emine; Barut, Abdulkadir; Ali, Kishwar; Pilatin, Abdulmuttalip; Nassani, Abdelmohsen A.
Introduction: The blue economy has become a pivotal framework for achieving sustainable development, emphasizing the responsible utilization of marine and coastal resources while preserving ecosystem integrity. Although biodiversity is central to fisheries, aquaculture, and coastal tourism, its direct role in shaping the blue economy remains underexplored. Furthermore, the interactions of biodiversity with other structural factors, such as financial development, institutional quality, and environmental pressures, are insufficiently addressed in existing studies. Methods: This study investigates the determinants of the blue economy by employing panel data from the world’s ten highest-income blue economies over the period 2000–2021. To address econometric challenges such as cross-sectional dependence, unit roots, and cointegration, second-generation panel techniques were applied. Long-term relationships were estimated using the Augmented Mean Group (AMG) estimator, and robustness was assessed through complementary econometric tests. Results: The empirical findings demonstrate that biodiversity exerts a positive and statistically significant effect on the blue economy. In contrast, financial development is negatively associated with blue economy performance. Institutional quality and per capita income are found to enhance blue economy outcomes, while CO₂ emissions exert a detrimental influence. Robustness checks confirm the stability and reliability of these results across alternative specifications. Discussion: The results underscore the vital role of biodiversity conservation in fostering sustainable growth within the blue economy framework. However, the negative effect of financial development suggests that existing financial structures do not sufficiently channel resources into environmentally sustainable marine activities. Strengthening institutional frameworks and aligning financial systems with ecological priorities are therefore critical. Moreover, reducing carbon emissions is indispensable to securing long-term resilience of marine ecosystems and ensuring the sustainability of blue economy activities.
Integrated molecular and morphological evidence reveals a new Rhodeus species (Cyprinidae: Acheilognathidae) from the Turkish Aegean basin, with a redescription of Rhodeus meridionalis
(Wiley, 2025) Kalaycı, Gökhan; Kurtul, Irmak; Bayçelebi, Esra; Kaya, Cüneyt; Turan, Davut
Rhodeus tugbae new sp. is described from some streams and rivers on the Turkish Aegean Sea coast. The new species is distinguished by a slightly sub-inferior mouth, a sharped predorsal keel, a body strongly compressed laterally and 3–4 scale rows between the anal-fin origin and the lateral series. This study contributes to understanding biodiversity and endemism in the freshwater ecosystems of the Aegean region. Rhodeus tugbae was compared to R. amarus and R. meridionalis, distributed in adjacent basin, using principal component analysis (PCA), and the results confirmed that R. tugbae differs from R. amarus and R. meridionalis. R. tugbae sp. nov. differed from its most closely related congener, R. meridionalis, by 14 diagnostic nucleotide substitution sites based on mitochondrial DNA (mtDNA) cyt b sequences. A revised description of R. meridionalis is also included due to the limited diagnostic features in the original description.
Association between cerebrospinal fluid acidosis and cerebral vasospasm and vacuolation following subarachnoid hemorrhage in a rabbit model
(Frontiers Media SA, 2025) Daltaban, İskender Samet; Vural, Sevilay; Aydın, Mehmet Dumlu; Gel, Mehmet Selim; Kanat, Ayhan
Introduction: Subarachnoid hemorrhage (SAH) is a life-threatening neurological emergency often complicated by delayed cerebral vasospasm, a major cause of morbidity and mortality. Clinical observations indicate that cerebrospinal fluid (CSF) acidosis can develop after aneurysmal SAH and may be associated with delayed cerebral ischaemia. Methods: We examined the relationship between CSF acidosis, vasospasm severity, and vacuolation in a rabbit model of SAH. Twenty-four hybrid rabbits were randomized into control (n = 5), sham-controlled (n = 5), and SAH (n = 14) groups. SAH was induced by injecting autologous blood into the fourth ventricle; sham-controlled animals received saline. CSF samples were collected on days 1, 7, and 14 for pH analysis, and basilar arteries were harvested on day 14 for determination of a vasospasm index (VSI) and vacuole density (VD). To explore the influence of acidosis severity, SAH animals were stratified into mild (CSF pH ≥ 7.20) and severe (CSF pH < 7.20) acidosis subgroups. Results: CSF pH was significantly lower in the SAH group than in control or sham-controlled animals (overall mean 7.22 ± 0.03 vs. 7.35 ± 0.02 and 7.31 ± 0.01; p < 0.05). While overall VSI did not differ among the groups, animals with severe acidosis displayed a markedly higher VSI than those with mild acidosis (2.83 ± 0.49 vs. 1.60 ± 0.64; p = 0.041). VD was elevated in both sham-controlled and SAH groups compared with controls (p = 0.009 and p = 0.002). Increased vacuolation in sham-controlled animals suggests that surgical manipulation alone can promote vacuole formation. There was a strong inverse correlation between CSF pH and VD (r = −0.75, p < 0.001), whereas no correlation was found between VSI and VD. Discussion: CSF acidosis, vacuolation, and vasospasm severity appear to be interconnected factors in the pathophysiology of SAH. CSF acidosis may contribute to vacuolation and, when profound, to vasospasm severity. However, vacuolation and vasospasm represent distinct pathological processes.
