Yazar "Kerimoğlu, Gökçen" için listeleme
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The ameliorative effect of Primula vulgaris on cisplatin-induced nephrotoxicity in rats and quantification of its phenolic components using LC-ESI-MS/MS
Turan, İbrahim; Canbolat, Deniz; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Türkmen Alemdar, Nihal; Menteşe, Ahmet; Aliyazıcıoğlu, Yüksel (Elsevier, 2023)Cisplatin (CDDP) is an important chemotherapeutic agent, accumulation of which in kidney tissue causes nephrotoxicity and renal failure. The aim of this study was to evaluate, for the first time in the literature, the ... -
Biochemical and pathological changes in the male rat kidney and bladder following exposure to continuous 900-MHz electromagnetic field on postnatal days 22-59
Türedi, Sibel; Kerimoğlu, Gökçen; Mercantepe, Tolga; Odacı, Ersan (Taylor & Francis Ltd, 2017)Purpose: To investigate the effect on male rat kidney and bladder tissues of exposure to 900-megahertz (MHz) electromagnetic field (EMF) applied on postnatal days 22-59, inclusive. Materials and methods: Twenty-four male ... -
Changes in testicular morphology and oxidative stress biomarkers in 60-day-old Sprague Dawley rats following exposure to continuous 900-MHz electromagnetic field for 1 h a day throughout adolescence
Hancı, Hatice; Kerimoğlu, Gökçen; Mercantepe, Tolga; Odacı, Ersan (Pergamon-Elsevier Science Ltd, 2018)The purpose of this study was to investigate the 60-day-old male rat testis following exposure to continuous 900-megahertz (MHz) electromagnetic field (EMF) throughout the adolescent period using histopathological and ... -
Chlorogenic acid ameliorates torsion/detorsion-induced testicular injury via decreasing endoplasmic reticulum stress
Kazaz, İlke Onur; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Türkmen Alemdar, Nihal; Doğan, Sedanur Yılmaz; Bostan, Serdar; Menteşe, Ahmet (Elsevier, 2022)Backround Testicular torsion (TT) is an urological emergency situation especially in adolescents and young men. The main pathophysiology of testicular torsion/detorsion (T/D) is ischemia-reperfusion (I/R) injury. I/R ... -
Effect of chrysin on endoplasmic reticulum stress in a rat model of testicular torsion
Kazaz, İlke Onur; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Alemdar, Nihal Türkmen; Akman, Ahmet Uğur; Çeküç, Ozan Can; Menteşe, Ahmet (Taylor & Francis Ltd., 2021)Background The purpose of this study was to evaluate the possible therapeutic effect of chrysin (CHS) on testicular torsion/detorsion (T/D) injury in vivo through the mechanisms of oxidative stress and endoplasmic reticulum ... -
Effect of Mitomycin C in the prevention of tendon adhesion after surgery and the effect of biomechanical stretching on tendon histology
Güvercin, Yılmaz; Abdioğlu, Ahmet Atilla; Baki, Mehmet Emre; Kerimoğlu, Gökçen; Karahasanoğlu, İlker; Yıldız, Mehmet (Türk El ve Üst Ekstremite Cerrahisi Derneği, 2021)Objective: In this study, optimal dose to reduce tendon adhesion, by using the dose-dependent fibroblast proliferation inhibition effect of Mit-C, and the level, which the tendon histologies are affected, using biomechanical ... -
The effects of dabigatran etexilate on fracture healing in rats An experimental study
Kerimoğlu, Servet; Onay, Atılgan; Güvercin, Yılmaz; Çıtlak, Atilla; Yenilmez, Engin; Kerimoğlu, Gökçen (Wolters Kluwer Medknow Publications, 2015)Background: Deep vein thrombosis leading to pulmonary embolism is one of the major complication after fracture. After a fracture occurs, the coagulation cascade activates thrombin, a protease that finally generates clotting. ... -
Effects of long-term exposure to 900 megahertz electromagnetic field on heart morphology and biochemistry of male adolescent rats
Kerimoğlu, Gökçen; Mercantepe, Tolga; Erol, Hüseyin Serkan; Turgut, Alpgiray; Kaya, Haydar; Çolakoğlu, Serdar; Odacı, Ersan (Taylor & Francis Ltd, 2016)The pathological effects of exposure to an electromagnetic field (EMF) during adolescence may be greater than those in adulthood. We investigated the effects of exposure to 900 MHz EMF during adolescence on male adult rats. ... -
Gallic acid attenuates torsion/detorsion-induced testicular injury in rats through suppressing of HMGB1/NF- κB axis and endoplasmic reticulum stress
Demir, Selim; Kazaz, İlke Onur; Kerimoğlu, Gökçen; Alemdar, Nihal Türkmen; Çolak, Fatih; Arıcı, Tuğba; Menteşe, Ahmet; Aliyazıcıoğlu, Yüksel (Elsevier, 2024)It was aimed to evaluate whether gallic acid (GA) have a beneficial effect in the testicular ischemia/reperfusion injury (IRI) model in rats for the first time. Testicular malondialdehyde, 8-hydroxy-2 '-deoxyguanosine, ... -
An investigation of the protective effect of rhododendron luteum extract on cisplatin-induced DNA damage and nephrotoxicity and biochemical parameters in rats
Turan, İbrahim; Canbolat, Deniz; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Alemdar, Nihal Türkmen; Menteşe, Ahmet; Aliyazıcıoğlu, Yüksel (University of Agriculture, 2023)The nephrotoxicity mechanisms caused by cisplatin (CP), which is used in the treatment of different types of cancer, include several processes, such as DNA damage, apoptosis, inflammation, and oxidative stress. This study ...