Yazar "Pınarbaş, Esra" için listeleme
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Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
Saral, Sinan; Kaya, Ali Koray; Topçu, Atilla; Öztürk, Aykut; Sümer, Ayşegül; Pınarbaş, Esra (Sakarya Üniversitesi, 2021)Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2) agonisti ve serotonin reseptör (5-HT2C) antagonisti olan antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ... -
Investigating the hepatic response to orlistat and white tea in rats on a high-fat diet
Çiftel; Klisic, Aleksandra; Çiftel, Enver; Mercantepe, Tolga; Yılmaz, Adnan; Çiftel, Sedat; Pınarbaş, Esra; Toraman, Merve Nur; Mercantepe, Filiz (MDPI, 2024)High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and ... -
Investigation of the effects of white tea on liver fibrosis: An experimental animal model
Yılmaz, Hülya Kılıç; Türker, Merve; Kutlu, Eda Yılmaz; Mercantepe, Tolga; Pınarbaş, Esra; Tümkaya, Levent; Atak, Mehtap (Wiley, 2024)Liver fibrosis is a common, progressive disease that affects millions of patients worldwide. In this study, it was aimed at investigating the effect of white tea on liver fibrosis in an in-vivo environment by creating an ... -
The nephroprotective effect of punica granatum peel extract on LPS-induced acute kidney injury
Şahin Aktura, Sena; Şahin, Kazım; Tümkaya, Levent; Mercantepe, Tolga; Topçu, Atilla; Pınarbaş, Esra; Yazıcı, Zihni Açar (MDPI, 2024)Sepsis is an exaggerated immune response resulting from systemic inflammation, which can damage tissues and organs. Acute kidney injury has been detected in at least one-third of patients with sepsis. Sepsis-associated ... -
Positive effects of white tea on breast cancer: N-methyl-N-nitrozourea intraductal induced breast carcinoma model
Mataracı Karakaş, Sibel; Yılmaz, Adnan; Mercantepe, Tolga; Topçu, Atilla; Pınarbaş, Esra (Elsevier, 2024)An objective of this study was to investigate the chemopreventive and therapeutic effects of white tea (WT) on breast cancer. Fifty Sprague-Dawley rats were divided into five groups: control, MNU, taxol, low dose white tea ... -
The protective effects of perindopril against acute kidney damage caused by septic shock
Kostakoğlu, Uğur; Mercantepe, Tolga; Yılmaz, Hülya Kılıç; Tümkaya, Levent; Batçık, Şule; Pınarbaş, Esra; Uydu, Hüseyin Avni (Springer/Plenum Publishers, 2021)Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ... -
Protective effects of trimetazidine and dexmedetomidine on liver injury in a mesenteric artery ischemia–reperfusion rat model via endoplasmic reticulum stress
Çiftel, Sedat; Mercantepe, Tolga; Aktepe, Rıza; Pınarbaş, Esra; Özden, Zülkar; Yılmaz, Adnan; Mercantepe, Filiz (MDPI, 2024)Background/Objectives: Acute mesenteric ischemia can lead to severe liver damage due to ischemia–reperfusion (I/R) injury. This study investigated the protective effects of trimetazidine (TMZ) and dexmedetomidine (DEX) ...