Yazar "Uygur, Meliha Melin" için listeleme
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Association of skin autofluorescence and carotid intima-media thickness in acromegaly patients
Background: The Pituitary Tumors Centers of Excellence (PTCOE) concept was established to provide a multimodal approach with careful management of comorbidities. Acromegaly, one of the main concerns of PTCOE per se, leads ... -
Clinical pharmacology of oral octreotide capsules for the treatment of acromegaly
Uygur, Meliha Melin; Villanova, Marta; Frara, Stefano; Giustina, Andrea (Touch Briefings, 2024)The primary goal of acromegaly treatment is to normalize biochemical parameters as it significantly reduces the risks of complications and comorbidities associated with the disease. First-line medical treatment is commonly ... -
High prevalence of morphometric vertebral fractures opportunistically detected on thoracic radiograms in patients with non-functioning pituitary adenoma
Frara, Stefano; Uygur, Meliha Melin; Bolamperti, Filippo; di Filippo, Luigi; Doga, Mauro; Ferrari, Francesc; Ferrari, Francesca; Losa, Marco; Mortini, Pietro; Giustina, Andrea (Springer, 2024)Purpose Vertebral fractures (VFs), the hallmark of skeletal fragility, have been reported as an emerging complication in patients with pituitary diseases associated with hormonal excess and/or deficiency, independently ... -
Medical management pathways for Cushing's disease in pituitary tumors centers of excellence (PTCOEs)
Giustina, A.; Uygur, Meliha Melin; Frara, S.; Barkan, A.; Biermasz, N. R.; Chanson, P; Freda, P.; Gadelha, M.; Haberbosch, L.; Kaiser, U. B.; Lamberts, S.; Laws, E.; Nachtigall, L. B.; Popovic, V.; Schilbach, K.; Lely, A. J. van der; Wass, J. A. H.; Melmed, S.; Casanueva, F. F. (Springer, 2025)PurposeA recent update of consensus guidelines for the management of Cushing's disease (CD) included indications for medical therapy. However, there is limited evidence regarding their implementation in clinical practice. ... -
Modern approach to bone comorbidity in prolactinoma
Uygur, Meliha Melin; Menotti, Sara; Santoro, Simona; Giustina, Andrea (Springer, 2024)Prolactinomas account for more than half of pituitary adenomas, and besides their clinical impact on fertility and gonadal function, they lead to detrimental effects on bone. Patients with prolactinoma are prone to ... -
New tools for bone health assessment in secreting pituitary adenomas
Uygur, Meliha Metin; Frara, Stefano; di Filippo, Luigi; Giustina, Andrea (Elsevier, 2023)Pituitary hormones regulate skeletal physiology, and excess levels affect bone remodeling and alter bone microstructure. Vertebral fractures (VFs) are an early phenomenon of impaired bone health in secreting pituitary ... -
Pilot study to define criteria for Pituitary Tumors Centers of Excellence (PTCOE): results of an audit of leading international centers
Giustina A.; Uygur M.M.; Frara S.; Barkan A.; Biermasz N.R.; Chanson P.; Freda P.; Gadelha M.; Kaiser U.B.; Lamberts S.; Laws E.; Nachtigall L.B.; Popovic V.; Reincke M.; Strasburger C.; van der Lely A.J.; Wass J.A.H.; Melmed S. (Springer, 2023)Purpose: The Pituitary Society established the concept and mostly qualitative parameters for defining uniform criteria for Pituitary Tumor Centers of Excellence (PTCOEs) based on expert consensus. Aim of the study was to ... -
Standards of care for medical management of acromegaly in pituitary tumor centers of excellence (PTCOE)
Giustina, Andrea; Uygur, Meliha Melin; Frara S.; Barkan A.; Biermasz N.R.; Chanson P.; Freda P.; Gadelha M.; Haberbosch L.; Kaiser U.B.; Lamberts S.; Laws E.; Nachtigall L.B.; Popovic V.; Reincke M.; van der Lely A.J.; Wass J.A.H.; Melmed S.; Casanueva F.F. (Springer, 2024)Purpose: A series of consensus guidelines on medical treatment of acromegaly have been produced in the last two decades. However, little information is available on their application in clinical practice. Furthermore, ... -
Vitamin D and malabsorptive gastrointestinal conditions: A bidirectional relationship?
Giustina, Andrea; di Filippo, Luigi; Allora, Agnese; Bikle, Daniel D.; Cavestro, Giulia Martina; Feldman, David; Latella, Giovanni; Minisola, Salvatore; Napoli, Nicola; Trasciatti, Silvia; Uygur, Melin; Bilezikian, John P. (Springer, 2023)This paper is one of the outcomes of the 5th International Conference "Controversies in Vitamin D" held in Stresa, Italy from 15 to 18 September 2021 as part of a series of annual meetings which was started in 2017. The ...
