Yazar "Yılmaz, Adnan" için listeleme
-
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
Dil, Eyüp; Topçu, Atilla; Mercantepe, Tolga; Tümkaya, Levent; Akyıldız, Kerimali; Saral, Sinan; Yılmaz, Adnan (Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
Antioxidative status and lipid peroxidation in kidney tissue of rats fed with vitamin B6-deficient diet
Keleş, Mustafa; Al, Behçet; Gümüştekin, Kenan; Demircan, Berna; Özbey, İsa; Akyüz, Mehmet; Yılmaz, Adnan; Demir, Elif; Uyanık, Abdullah; Zipyak, Tevfik; Taysi, Seyithan (Taylor & Francis, 2010)Introduction: The aim of this study was to evaluate lipid peroxidation (LP) and free radical scavenging enzyme activities in kidney tissue of vitamin B6-deficient rats. Material and Methods: The rats were divided into ... -
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Akyıldız, Kerimali; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar; Yılmaz, Adnan (Elsevier, 2021)It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ... -
Association of insulin resistance with overactive bladder in female patients
Uzun, Hakkı; Yılmaz, Adnan; Kemik, Ahu; Zorba, Orhan Ünal; Kalkan, Mehmet (Korean Continence Soc, 2012)Purpose: Metabolic syndrome and obesity have been advocated to be risk factors for the development of overactive bladder (OAB). Additionally, insulin resistance is the underlying mechanism of metabolic syndrome. We aimed ... -
Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress
Saral, Özlem; Şahin, Hüseyin; Saral, Sinan; Alkanat, Mehmet; Akyıldız, Kerimali; Topçu, Atilla; Yılmaz, Adnan (Elsevier Ireland Ltd., 2021)Chronic stress is a potential problem associated with anxiety, depression, and cognitive dysfunction. Bee pollen, a powerful antioxidant, has many therapeutic effects. In this study, we aimed to examine the effects of one ... -
Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
Çınar, Seda; Tümkaya, Levent; Mercantepe, Tolga; Saral, Sinan; Rakıcı, Sema; Yılmaz, Adnan; Topçu, Atilla; Şen, Ahmet; Karakaş, Sibel (Springer, 2021)Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ... -
Can thiamine pyrophosphate prevent desflurane induced hepatotoxicity in rats?
Arslan, Aynur; Kuyrukluyıldız, Ufuk; Binici, Orhan; Çetin, Nihal; Balcı, Mecdi Gürhan; Kuzucu, Mehmet; Yılmaz, Adnan; Altuner, Durdu; Çoban, Taha Abdülkadir (Acta Cirurgica Brasileira, 2016)PURPOSE: To investigate the effects of thiamine pyrophosphate (TPP) against desflurane induced hepatotoxicity. METHODS: Thirty experimental animals were divided into groups as healthy (HG), desflurane control (DCG), TPP ... -
Chitosan-coated scorpion venom ameliorates acute lung injury caused by klebsiella pneumoniae
Oskay, Burak; Şahin, Kazım; Çalışkan, Figen; Mercantepe, Tolga; Aktura, Sena Şahin; Tümkaya, Levent; Topçu, Atilla; Yılmaz, Adnan; Karakaş, Sibel Mataracı; Yazıcı, Zihni Açar (Springer, 2024)Nosocomial infections caused by antibiotic-resistant bacteria result in significant economic costs and human health issues, including acute lung injury. The purpose of this study was to investigate the scorpion venom in ... -
Cholesterol forms and traditional lipid profile for projection of atherogenic dyslipidemia: lipoprotein subfractions and erythrocyte membrane cholesterol
Uydu, Hüseyin Avni; Bostan, Mehmet; Atak, Mehtap; Yılmaz, Adnan; Demir, Adem; Akcan, Buket; Sümer, Fatih; Baltaş, Nimet; Karadağ, Zakir; Uğurlu, Yavuz; Örem, Asım (Springer, 2014)Atherogenic dyslipidemia characterized by abnormal changes in plasma lipid profile such as low high-density lipoprotein (HDL) and increased triglyceride (TG) levels is strongly associated with atherosclerotic diseases. We ... -
The clinical utility of pleural YKL-40 levels in diagnosing pleural effusions
Kayhan, Servet; Gümüş, Aziz; Çınarka, Halit; Murat, Naci; Yılmaz, Adnan; Bedir, Recep; Şahin, Ünal (Pioneer Bioscience Publ Co, 2013)Background and objective: Recent evidence suggests that YKL-40 is a relatively new biomarker of inflammation and it is involved in the pathogenesis of several pulmonary diseases. Details of serum and pleural YKL-40 in ... -
Comparative analysis of epigallocatechin-3-gallate and TNF-alpha inhibitors in mitigating cisplatin-induced pancreatic damage through oxidative stress and apoptosis pathways
Çiftel, Enver; Mercantepe, Filiz; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Çiftel, Serpil (Springer, 2024)Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as cancer cells. In this study, we aimed to investigate the effect of ... -
Comparison of effects of dexmedetomidine and amifostine against X-ray radiation-induced parotid damage
Şafak, Gökhan; Çeliker, Metin; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema; Çınar, Seda; Yılmaz, Adnan; Terzi, Suat; Demir, Emine; Erdivanlı, Özlem Çelebi; Coşkun, Zerrin Özergin; Karakaş, Sibel; Birinci, Mehmet; Dursun, Engin (Springer, 2022)Radiotherapy can be employed as a therapeutic modality alone in the early stages of cancer and is used together with other treatments such as surgery and chemotherapy in more advanced stages. However, exposure to ionizing ... -
Determination of tritium concentrations in humans before the development of a nuclear power plant in Turkey
Dizman, Serdar; Yılmaz, Adnan; Keser, Recep (Taylor & Francis Ltd, 2015)The most widely used method to determine the level of tritium in humans is testing urine. Tritium concentrations in urine samples of 100 persons aged 18-66 years selected randomly from a pilot region in Turkey were analysed. ... -
Dexmedetomidine alleviates vacuolization and necrosis in tubular epithelial cells induced by aortic cross-clamping
Ergene, Şaban; Hemşinli, Doğuş; Karakişi, Sedat Ozan; Tümkaya, Levent; Mercantepe, Tolga; Yılmaz, Adnan (Verduci Publisher, 2023)OBJECTIVE: Acute kidney inju-ry (AKI) is one of the main causes of mortality in patients undergoing emergency surgery due to an abdominal aortic aneurysm. This study aimed to determine the potential nephroprotec-tive ... -
Dexmedetomidine attenuates pneumocyte apoptosis and inflammation induced by aortic ischemia-reperfusion injury
Hemşinli, Doğuş; Tümkaya, Levent; Ergene, Şaban; Karakişi, Sedat Ozan; Mercantepe, Tolga; Yılmaz, Adnan (Taylor & Francis Ltd., 2022)Objective Despite significant improvements in interventional vascular aneurysm repair procedures and intensive care patient management, there has been no significant decrease in mortality due to ruptured abdominal aortic ... -
Does radiofrequency radiation from mobile phones affect the formation of parotid gland malignancy? An experimental study
Özergin Coşkun, Zerrin; Tümkaya, Levent; Yılmaz, Adnan; Dursun, Engin; Mercantepe, Tolga; Kalkan, Yıldıray; Ersöz, Şafak (Sage Publications, 2024)Objectives: The use of mobile phone is increasing around the world. Although it is beneficial in terms of communication, the electromagnetic radiations emitted by mobile phones may cause undesirable biological effects on ... -
The effect of dexmedetomidine on liver injury secondary to lower extremity ischemia-reperfusion in a diabetic rat model
Kartal, Seyfi; Şen, Ahmet; Tümkaya, Levent; Erdivanlı, Başar; Mercantepe, Tolga; Yılmaz, Adnan (Taylor & Francis Ltd., 2021)Introduction: In this study, we aimed to evaluate the hepatic protective effects of dexmedetomidine in the lower extremity ischemia-reperfusion model in diabetic rats biochemically and histopathologically. Methods: Rats ... -
Effect of ethyl acetate extract of usnea longissima on esophagogastric adenocarcinoma in rats
Mammadov, Renad; Süleyman, Bahadır; Altuner, Durdu; Demirci, Elif; Çetin, Nihal; Yılmaz, Adnan; Baykal, Hüseyin; Alpcan, Hilal; Turumtay, Emine Akyüz; Süleyman, Halis (Acta Cirurgica Brasileira, 2019)Purpose: To investigate the effects of the EtOAc extract of U. longissima which is uninvestigated previously on esophagogastric cancer induced in rats with N-methyl-N-nitro-N-nitrosoguanidin (MNNG). Methods: the anticancer ... -
The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development
Bedir, Recep; Tümkaya, Levent; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Yılmaz, Adnan; Şahin, Osman Zikrullah (Informa Healthcare, 2015)Background: the aim of this study was to investigate the effects of exposure to a 900-MHz electromagnetic field (EMF) produced by mobile phones on the renal development of prenatal rats. Histopathological changes and ...
