Recep Tayyip Erdoğan Üniversitesi Kurumsal Akademik Arşivi
DSpace@RTEÜ, Recep Tayyip Erdoğan Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
The prevalence and correlates of arterial stiffness in patients with treated hypertension: oscillometric pulse wave analysis during 24-h ambulatory blood pressure monitoring
(Wiley, 2026) Tüfekçi, Damla; Sahutoğlu, Tuncay; Kara, Ekrem
Background: We investigated the prevalence and correlates of arterial stiffness in treated hypertension using oscillometric pulse wave analysis during 24-h ambulatory blood pressure monitoring (ABPM). Methods: In this single-center cross-sectional study, 131 patients (median age 51.0 years, range 17.0–86.0; 54.2% female) underwent 24-h ABPM. Measurements included 24-h, daytime, and night-time SBP, DBP, MAP, pulse pressure, dipping status, and estimated pulse wave velocity (ePWV) derived by the Mobil-O-Graph (ARCSolver; age/SBP-dependent). Results: High ePWV (> 9 m/s) was present in 16.8% of patients. Compared with low/moderate ePWV, the high-ePWV subgroup was older (p < 0.001) and had higher FPG (p < 0.001), higher creatinine and lower eGFR (both p < 0.001), greater proteinuria (p = 0.006), and a lower frequency of systolic dipper status (p = 0.033). In simple correlations, 24-h ePWV was correlated positively with 24-h, daytime, and night-time values of DBP, MAP, and pulse pressure, BMI, FPG, creatinine, uric acid, and proteinuria, and negatively with systolic dipping, diastolic dipping, albumin, and eGFR. However, after adjusting for age, age2, and 24-h SBP, the partial correlation analysis revealed that ePWV was negatively correlated only with FPG (r = −0.216, p = 0.014) and hsCRP (r = −0.220, p = 0.031) and positively correlated only with total cholesterol (r = 0.243, p = 0.043) and LDL (r = 0.359, p = 0.004). Conclusion: Elevated ePWV identifies a high-risk phenotype in treated hypertension, characterized by advanced age and renal impairment. However, these associations appear intrinsic to the algorithm’s reliance on age and SBP. After adjusting for these inputs, ePWV did not exhibit independent associations with clinical parameters, suggesting it should be viewed as an integrated derivative of age and blood pressure rather than a separate physiological measure. ePWV values should be interpreted with caution, recognizing their inherent dependence on algorithmic inputs.
Pelvic floor dysfunction and rehabilitation in neurological disorders: bridging pathophysiology with multidisciplinary approaches—a focused mini-review
(SAGE Publications Inc., 2026) Birben Kurt, Tuğba; Çağlar, Derya
Background.: Pelvic floor dysfunction (PFD) is a frequent yet underrecognized complication of neurological disorders such as multiple sclerosis (MS), Parkinson’s disease (PD), and stroke. Its multifactorial pathophysiology involves complex neural mechanisms affecting bladder, bowel, and sexual function, often resulting in decreased quality of life and psychosocial distress. Objective.: This focused mini-review aims to synthesize current evidence on the pathophysiology, clinical features, and rehabilitation approaches for neurogenic PFD in major neurological conditions. Methods.: A targeted literature search was performed in PubMed, Scopus, and Web of Science databases to identify clinical and experimental studies published between 1990 and 2025 addressing urinary and PFD in neurological populations. Special attention was given to rehabilitation-based interventions such as pelvic floor muscle training (PFMT), biofeedback, neuromuscular electrical stimulation (NMES), and percutaneous tibial nerve stimulation. Findings.: Neurogenic PFD is highly prevalent, with up to 90% of MS patients, 60% of PD patients, and nearly half of stroke survivors experiencing urinary symptoms. Conservative rehabilitation, particularly PFMT combined with biofeedback and NMES, improves muscle function, reduces incontinence frequency, and enhances quality of life. However, standardized rehabilitation protocols are lacking, and adherence remains a major barrier. Conclusion.: Evidence supports a multidisciplinary rehabilitation approach integrating PFMT and adjunct modalities for neurogenic PFD. Further large-scale randomized studies are required to establish standardized, evidence-based clinical guidelines.
Does women’s political participation matter in carbon emissions reduction? A panel data analysis of BRICS-TM
(SAGE Publications Inc., 2026) Erenel, Deniz; Peçe, Halil; Bilici, İlhan
Although previous studies have investigated the impact of various determinants on environmental degradation, there has been relatively minimal research on the impact of women’s political participation (WP) on carbon emissions (CO2). Considering the research gaps, we examine the relationship between WP and CO2 as well as their underlying mechanisms in Brazil, Russia, India, China, South Africa, Turkey, and Mexico (BRICS-TM), the world’s largest energy consumers and the largest CO2 emitters. For this purpose, the novel Method of Moment Quantile Regression (MMQR) technique is applied as a robust estimation method alongside Fully Modified Ordinary Least Square (FMOLS), Dynamic Ordinary Least Square (DOLS), and Canonical Cointegration Regression (CCR) estimations. The findings indicate that a 1% rise in WP leads to a reduction in CO2 in the FMOLS, DOLS, and CCR techniques by 0.022%, 0.090%, and 0.024%, respectively. Further, the MMQR technique demonstrates that WP reduces to CO2 by 0.071% to 0.122% across all quantiles from the 10th to 90th. The study is also augmented with additional variables, such as renewable energy consumption (REC), economic growth (EG), energy consumption (EC), and trade openness (TO) to enhance the robustness of the CO2 function. EG, EC, and TO exert a positive impact on CO2, while REC reduces it. The results highlight that increasing women’s political participation can pave the way for legislation that particularly supports green economy and sustainable development in BRICS-TM.
Life-threatening presentation of pulmonary hydatid cyst with hemoptysis and hydatoptysis
(Sociedade Brasileira de Medicina Tropical, 2026) Topaloğlu, Ömer; Topaloğlu, Elvan Şentürk; Türüt, Hasan
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