Yayıncı "Academic Press Inc Elsevier Science" için listeleme
Toplam kayıt 19, listelenen: 1-19
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Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
(Academic Press Inc Elsevier Science, 2019)A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ... -
Design, synthesis and molecular modeling studies on novel moxifloxacin derivatives as potential antibacterial and antituberculosis agents
(Academic Press Inc Elsevier Science, 2019)Twenty-one novel alkyl/acyl/sulfonyl substituted fluoroquinolone derivatives were designed, synthesized and evaluated for their anti-tuberculosis and antibacterial activity. the targeted compounds were synthesized by the ... -
Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats
(Academic Press Inc Elsevier Science, 2020)..... -
High cryptic diversity of bitterling fish in the southern West Palearctic
(Academic Press Inc Elsevier Science, 2019)South-east Europe, along with the adjacent region of south-west Asia, is an important biodiversity hotspot with high local endemism largely contributed by contemporary continental lineages that retreated to southern refugia ... -
Noble metal nanoparticles supported on activated carbon: Highly recyclable catalysts in hydrogen generation from the hydrolysis of ammonia borane
(Academic Press Inc Elsevier Science, 2019)Noble metal nanoparticles including rhodium, ruthenium and palladium have been extensively used in catalysis field. Since their limited abundance and high cost, many methods have been developed to obtain highly active and ... -
Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA binding affinities
(Academic Press Inc Elsevier Science, 2020)A series of new 2-amino-4-aryl-6-pyridopyrimidines, and their N-alkyl bromide derivatives were designed and synthesized by employing methyl substituted azachalcones. These novel compounds were evaluated and compared to the ... -
Novel imidazo[2,1-b] [1,3,4]thiadiazole (ITD) hybrid compounds: Design, synthesis, efficient antibacterial activity and antioxidant effects
(Academic Press Inc Elsevier Science, 2019)In this study, novel imidazo[2,1-b] [1,3,4]thiadiazole (ITD) compounds were synthesized and their antimicrobial and antioxidant capacity was examined. the C-2 position of the ITD structure was fixed with the 3,4-hydroxybenzene ... -
A passive acoustic based system to locate leak hole in underwater natural gas pipelines
(Academic Press Inc Elsevier Science, 2018)Underwater natural gas pipelines can be punctured for a variety of reasons, but the most notable are corrosion and aging. This study proposes a novel passive acoustic based system, to detect acoustic signals, locate the ... -
Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies
(Academic Press Inc Elsevier Science, 2019)A series of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives was obtained via several steps sequential reactions of phenyl piperazine. Then, these compounds were converted to the corresponding fluoroquinolone hybrids ... -
A simple and efficient synthesis of benzimidazoles containing piperazine or morpholine skeleton at C-6 position as glucosidase inhibitors with antioxidant activity
(Academic Press Inc Elsevier Science, 2018)A novel 2-(aryl)-6-morpholin-4-yl(or 4-methylpiperazin-1-yl)-1H-benzimidazole derivatives were designed and expeditiously synthesized starting from 5-morpholin-4-yl(or 4-methylpiperazin-1-yl)-2-nitroaniline with various ... -
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
(Academic Press Inc Elsevier Science, 2016)A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ... -
Synthesis and biological evaluation of new 2,4,6-trisubstituted pyrimidines and their N-alkyl derivatives
(Academic Press Inc Elsevier Science, 2019)A series of new 2,4,6-trisubstituted pyrimidines and their N-alkyl bromide derivatives were prepared based upon methoxy substituted azachalcones as the starting materials. All newly synthesized compounds were screened for ... -
Synthesis and molecular docking studies of some novel antimicrobial benzamides
(Academic Press Inc Elsevier Science, 2020)Common use of classical antibiotics has caused to the growing emergence of many resistant strains of pathogenic bacteria. Therefore, we aimed to synthesize a number of N-(2-hydroxy-(4 or 5)-nitrophenyl)benzamide derivatives ... -
Synthesis and molecular docking study of some novel 2,3-disubstituted quinazolin-4(3H)-one derivatives as potent inhibitors of urease
(Academic Press Inc Elsevier Science, 2018)A new series of 2,3-disubstituted quinazolin-4(3H)-one compounds including oxadiazole and furan rings was synthesized. Their inhibitory activities on urease were assessed in vitro. All newly synthesized compounds exhibited ... -
Synthesis of 5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-one's aryl Schiff base derivatives and investigation of carbonic anhydrase and cholinesterase (AChE, BuChE) inhibitory properties
(Academic Press Inc Elsevier Science, 2019)Carbonic anhydrase enzymes (EC 4.2.1.1, CAs) are metalloenzyme families that catalyze the rapid conversion of H2O and CO2 to HCO3- and H+. CAs are found in different tissues where they participate in various significant ... -
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
(Academic Press Inc Elsevier Science, 2020)In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ... -
Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities
(Academic Press Inc Elsevier Science, 2019)A new series of quinazolinone derivatives containing triazole, thiadiazole, thiosemicarbazide functionalities was synthesized and then screened for their in vitro urease inhibition properties. Most of the compounds showed ... -
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
(Academic Press Inc Elsevier Science, 2018)In this study, a new series of benzimidazole and bisbenzimidazole derivatives were prepared via the reaction of iminoester hydrochlorides and o-phenylenediamines and then screened for their lipase inhibition properties. ... -
Theoretical and experimental evaluation of thermoelectric performance of alkaline earth filled skutterudite compounds
(Academic Press Inc Elsevier Science, 2020)Skutterudite compounds are one of the most promising thermoelectric materials that can be used for intermediate power generation applications because of their excellent thermoelectric and mechanical properties. in spite ...
