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Identification of novel inhibitors of the ABC transporter BmrA

Serçinoğlu, Onur; Şentürk, Duygu; Altınışık Kaya, Fatma Ece; Avcı, Fatma Gizem; Frlan, Rok; Tomašič, Tihomir; Özbek, Pemra; Orelle, Cédric; Jault, Jean-Michel; Sarıyar Akbulut, Berna (Academic Press Inc., 2020)

The resistance of microbes to commonly used antibiotics has become a worldwide health problem. A major underlying mechanism of microbial antibiotic resistance is the export of drugs from bacterial cells. Drug efflux is ...
Synthesis, biological evaluation (antioxidant, antimicrobial, enzyme inhibition, and cytotoxic) and molecular docking study of hydroxy methoxy benzoin/benzil analogous

Yaylı, Nurettin; Kılıç, Gözde; Kahriman, Nuran; Kanbolat, Şeyda; Bozdeveci, Arif; Karaoğlu, Şengül Alpay; Aliyazıcıoğlu, Rezzan; Sellitepe, Hasan Erdinç; Doğan, İnci Selin; Aydın, Ali; Tatar, Gizem (Academic Press Inc., 2021)

In this work, due to the biological activity evaluation, a series of hydroxy methoxy benzoins (1–8), benzils (10–16) and methoxy benzoin/benzil-O-β-D-glucosides (17–28) were synthesized. Antioxidant (FRAP, CUPRAC, DPPH), ...