dc.contributor.author | Şahin, Osman Zikrullah | |
dc.contributor.author | Şahin, Serap Baydur | |
dc.contributor.author | Ayaz, Teslime | |
dc.contributor.author | Karadağ, Zakir | |
dc.contributor.author | Türkyılmaz, Kemal | |
dc.contributor.author | Aktaş, Ezgi | |
dc.contributor.author | Bostan, Mehmet | |
dc.date.accessioned | 2020-12-19T19:57:11Z | |
dc.date.available | 2020-12-19T19:57:11Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Sahin, O. Z., Sahin, S. B., Ayaz, T., Karadag, Z., Turkyilmaz, K., Aktas, E., & Bostan, M. (2015). The impact of hypertension on retinal nerve fiber layer thickness and its association with carotid intima media thickness. Blood pressure, 24(3), 178–184. https://doi.org/10.3109/08037051.2014.1000562 | en_US |
dc.identifier.issn | 1651-1999 | |
dc.identifier.uri | https://doi.org/10.3109/08037051.2014.1000562 | |
dc.identifier.uri | https://hdl.handle.net/11436/2824 | |
dc.description | WOS: 000354191800007 | en_US |
dc.description | PubMed: 25658169 | en_US |
dc.description.abstract | Objective. Our aim was to investigate retinal nerve fi ber layer (RNFL) thickness in hypertensive patients using spectraldomain optical coherence tomography (SD-OCT) and to evaluate the relationship between RNFL thickness and carotid intima media thickness (CIMT). Methods. This study included 59 patients with hypertension (HT) (53.6 +/- 10.7 years) and 54 age-matched healthy controls (51.0 +/- 8.1 years). We evaluated anthropometric and metabolic parameters as well as RNFL and CIMT measurements in patients with hypertension and controls. Results. the average RNFL thickness was 86.60 +/- 10.86 mu m in hypertensive patients and 93.63 +/- 7.30 mu m in healthy controls (p < 0.001). Selective thinning of the RNFL was found in the superior and inferior quadrants. Mean CIMT values were higher in patients with HT (0.80 +/- 0.15 mm) than the healthy subjects (0.71 +/- 0.1 mm) (p < 0.001). the average, inferior and nasal RNFL thickness were negatively associated with diastolic blood pressure respectively (r= 0.112, r= 0.210, r= 0.225). There was an inverse correlation between RNFL thickness in the average and superior retinal quadrant and CIMT (r- =0.201, r= -0.185). There were no correlations between RNFL thickness and age, body mass index, fasting plasma glucose, lipid parameters, high-sensitive C-reactive protein and microalbuminuria. Conclusion. RNFL thickness is reduced in hypertensive patients and may be associated with atherosclerosis. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Carotid intima media thickness | en_US |
dc.subject | Hypertension | en_US |
dc.subject | Retinal fiber layer thickness | en_US |
dc.title | The impact of hypertension on retinal nerve fiber layer thickness and its association with carotid intima media thickness | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Şahin, Osman Zikrullah | |
dc.contributor.institutionauthor | Şahin, Serap Baydur | |
dc.contributor.institutionauthor | Ayaz, Teslime | |
dc.contributor.institutionauthor | Karadağ, Zakir | |
dc.contributor.institutionauthor | Türkyılmaz, Kemal | |
dc.contributor.institutionauthor | Aktaş, Ezgi | |
dc.contributor.institutionauthor | Bostan, Mehmet | |
dc.identifier.doi | 10.3109/08037051.2014.1000562 | |
dc.identifier.volume | 24 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 178 | en_US |
dc.identifier.endpage | 184 | en_US |
dc.relation.journal | Blood Pressure | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |