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dc.contributor.authorKaya, M.
dc.contributor.authorMENTEŞE, E.
dc.contributor.authorSÖKMEN, B.B.
dc.contributor.authorAKÇAY, H.T.
dc.date.accessioned2020-12-19T20:17:57Z
dc.date.available2020-12-19T20:17:57Z
dc.date.issued2020
dc.identifier.issn0022-2860
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2020.128870
dc.identifier.urihttps://hdl.handle.net/11436/4466
dc.description.abstractIn present study, the novel peripherally [3-methyl-5-oxo-4-(4-phenoxyphenyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl] substituted Zn(II), Cu(II), Co(II) phthalocyanines were synthesized and characterized spectroscopically. The light absorption/emission behavior of the synthesized phthalocyanines were determined by UV-Vis and fluorescence spectroscopy. The fluorescence quantum yields of the novel phthalocyanine Zn(II) complex in different solvents were calculated. Besides, the urease inhibition activities of the novel compounds were investigated. All synthesized phthalocyanines have a superior inhibitory activity on urease enzyme, while novel phthalocyanines Cu(II) showed the best inhibitory effect against jack bean urease with IC50 values of 0.0035 ±0.0010 µM. © 2020 Elsevier B.V.en_US
dc.description.sponsorshipRecep Tayyip Erdogan Üniversitesi: FBA-2019-948en_US
dc.description.sponsorshipThis study was supported by Recep Tayyip Erdogan University - Research Funding - (Project no. FBA-2019-948).en_US
dc.language.isoengen_US
dc.publisherElsevier B.V.en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAggregationen_US
dc.subjectFluorescenceen_US
dc.subjectPhthalocyanineen_US
dc.subjectUrease inhibition activityen_US
dc.titleThe determination of molecular dynamic properties of Novel 5-oxo-1,2,4-triazole phthalocyanines and investigation of their urease inhibition propertiesen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜen_US
dc.identifier.doi10.1016/j.molstruc.2020.128870
dc.identifier.volume1222en_US
dc.relation.journalJournal of Molecular Structureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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