Ara
Toplam kayıt 25, listelenen: 11-20
Microwave assisted synthesis of some novel 2-(3-Chlorobenzyl)-1H-benzimidazole derivatives and determination of their antimicrobial activity and pKa values
(Chiminform Data S A, 2015)
In the present research, synthesis of new 2-(3-chlorobenzyl)-1H-benzimidazole derivatives bearing N-benzylidene, 1,2,4-triazole and N-acylhydrazone moiety is investigated. These novel compounds have been tested for their ...
Microwave-assisted synthesis of some new benzimidazole derivatives with their antimicrobial activity
(Bentham Science Publ Ltd, 2015)
2-(2-Chlorobenzyl)-1H-benzimidazole (2) was prepared from the reaction of o-phenylenediamine and ethylimido-o-chlorophenylacetate hydrochloride (1) under microwave irradiation. the acetate and hydrazide derivatives of 2(2- ...
Microwave assisted synthesis and anti-lipase activity of some new fluorine-containing benzimidazoles
(Georg Thieme Verlag Kg, 2015)
In this study, a new series of fluorine containing benzimidazoles (4a-l) and bisbenzimidazoles (6a-c, 8) were synthesized by the reaction of o-phenylenediamines with iminoester hydrochlorides (3a-l, 7) in methanol under ...
Determination of biological activities and pka at drug active substance in some bisbenzimidazoles derivatives
(Raman Publ, 2016)
Bisbenzimidazole derivatives have known different structures as drug active substance were evaluated for their biological activities such as antiviral and anti-tumor activities. in addition, acid dissociation constants ...
Novel coumarin derivatives containing a triazole moiety: A study on synthesis, cytotoxicity, membrane dysfunction, apoptosis, cell cycle, and antiangiogenic effects
(Bentham Science Publications, 2022)
Background: Coumarin is a functional compound with a pronounced wide range of biological activities and has recently been shown to have anticancer effects on various human cancer cells. Cisplatin is widely used in treating ...
Study of antıoxidant, antimicrobial and anti-xanthine oxidase activities of some 5,6-dimethyl-2-(substituted)-1h-benzimidazoles and their acylhydrazide derivatives
(Raman Publ, 2017)
In this study, a series of 5,6-dimethy1-2-(4-fluoro/chloro/bromo/methyl/nitrobenzy1)-1Hbenzimidazoles were screened for their bovine milk xanthine oxidase (XO) inhibition, antioxidant and antimicrobial activities. Compounds ...
Synthesis and antioxidant evaluation of some novel benzimidazole derivatives containing a triazole nucleus
(Bentham Science Publ Ltd, 2017)
Various benzimidazole compounds containing a triazole nucleus were synthesized and screened for their antioxidant activies. the structures of newly synthesized compounds were characterized by H-1 NMR, C-13 NMR and elemental ...
Microwave-assisted synthesis of benzimidazoles and their derivatives from 1994 to 2016-A review
(Bentham Science Publ Ltd, 2017)
Background: the use of microwave irradiation is an important development for the synthesis of benzimidazoles in the 21st century, and in recent years, microwave-assisted heterocyclic synthesis has gained significant attention ...
Synthesis and antimicrobial activity of some new triazole bridged benzimidazole substituted phthalonitrile and phthalocyanines
(Editura Acad Romane, 2018)
In this study, some new phthalonitriles and metallophthalocyanines (Zn, Ni, Co, and Cu) containing triazole bridged benzimidazole moieties were synthesized starting from 2-(3-methylbenzyl)-1H-benzimidazole Newly synthesized ...
Microwave assisted synthesis of cournarins: A review from 2007 to 2018
(Bentham Science Publ Ltd, 2018)
Background: Microwave heating has been shown to be an invaluable technology for medicinal chemistry and drug discovery applications. Recently, it has been used for heterocyclic synthesis increasingly. This review article ...