Ara
Toplam kayıt 118, listelenen: 111-118
Effects of hippophae rhamnoides extract on oxidative mucosal injury induced by cisplatin in rat jejunum
(Scientific Publishers of India, 2018)
Objectives: We aimed to assess the effect of Hippophae rhamnoides extract (HR) on oxidative stress induced by cisplatin (Cis) in rat small intestine tissue by evaluating the biochemical and gene expression levels and ...
Arbutin abrogates cisplatin-induced hepatotoxicity via upregulating Nrf2/HO-1 and suppressing genotoxicity, NF-κB/iNOS/TNF-α and caspase-3/Bax/Bcl2 signaling pathways in rats
(Oxford University Press, 2024)
Background: Cisplatin is a potent anticancer agent widely employed in chemotherapy. However, cisplatin leads to toxicity on non-targeted healthy organs, including the liver. We investigated the hepatoprotective mechanism ...
Evaluation of the protective effect of coenzyme Q10 against x-ray irradiation-induced ovarian injury
(Wiley, 2024)
Aim: This study focused on the anti-oxidant and anti-apoptotic effects of CoQ10 in ovaries exposed to pelvic radiation. Methods: Thirty-two female rats were randomly assigned into four groups. Group I (control group), Group ...
Did diet compliance and remission reduce oxidative stress in celiac patients?
(Associacao Medica Brasileira, 2024)
OBJECTIVE: We aimed to examine the effect of remission status on thiol–disulfide homeostasis in celiac patients and thus to indirectly determine the effect of oxidative stress and inflammation caused by non-compliance with ...
Gallic acid attenuates torsion/detorsion-induced testicular injury in rats through suppressing of HMGB1/NF- κB axis and endoplasmic reticulum stress
(Elsevier, 2024)
It was aimed to evaluate whether gallic acid (GA) have a beneficial effect in the testicular ischemia/reperfusion injury (IRI) model in rats for the first time. Testicular malondialdehyde, 8-hydroxy-2 '-deoxyguanosine, ...
Usnic acid alleviates testicular ischemia/reperfusion injury in rats by modulating endoplasmic reticulum stress
(Elsevier, 2024)
Testicular torsion (TT) is a urological condition that can result in infertility in men. The etiopathogenesis of TT includes ischemia/reperfusion injury (IRI) characterized by oxidative stress (OS), inflammation and apoptosis ...
Gentisic acid attenuates 5-fluorouracil-induced ovotoxicity in rats via modulating Nrf2 signalling: An experimental approach
(Elsevier, 2024)
5-Fluorouracil (5-FU) is the third most used chemotherapeutic in the world with its anticancer effect resulting from its potential to block DNA replication. Like other cytotoxic agents, 5-FU has side effects on healthy ...
Alleviating effect of alpha-pinene on testicular torsion and detorsion injury in rats
(Galenos Yayınevi, 2023)
Objective: It was aimed to evaluate whether alpha-pinene (AP) had a beneficial effect in the testicular ischemia/reperfusion injury (IRI) model for the first time. Materials and Methods: Testicular malondialdehyde, total ...