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The effects of dexmedetomidine on early acute kidney injury in severely burned rats
(Verduci Publisher, 2023)
OBJECTIVE: Burns are a global
medical and economic problem. In addition to
high costs, the lengthy therapeutic process and
the emotional trauma experienced by patients
and their families indirectly worsen the socioeconomic ...
Radioprotective effects of dexmedetomidine on X-ray-induced testicular damage
(Verduci Publisher, 2023)
OBJECTIVE: Approximately 70%
of cancer patients require radiotherapy. However, despite its effectiveness in the treatment of
cancer, radiotherapy can also affect and damage
surrounding healthy tissues in addition to ...
Effects of infliximab against carbon tetrachloride-induced spleen toxicity in rats
(Verduci Publisher, 2023)
OBJECTIVE: Carbon tetrachloride (CCl4
) is a non-polar molecule used in industry in grain curing, insect-killing and especially in
the production of chlorofluorocarbons. It is estimated that an average of 70,000 industry ...
Neuroprotective effects of Vaccinium myrtillus on damage-related brain injury
(2023)
Traumatic brain injury may trigger the secondary brain injury, which has the potential to be reversible and thus
preventable. Anthocyanins are phylotherapeutic plants, which are reported to exhibit anti-inflammatory ...
Dexmedetomidine alleviates vacuolization and necrosis in tubular epithelial cells induced by aortic cross-clamping
(Verduci Publisher, 2023)
OBJECTIVE: Acute kidney inju-ry (AKI) is one of the main causes of mortality in patients undergoing emergency surgery due to an abdominal aortic aneurysm. This study aimed to determine the potential nephroprotec-tive ...
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)
Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with
proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ...
Resveratrol attenuates degeneration and apoptosis of cardiomyocytes induced by aortic clamping
(2023)
Introduction: Objective: To investigate the potential beneficial effects of resveratrol
(RVT) against ischemia-reperfusion injury of myocardial tissue during surgical
treatment of ruptured abdominal aortic aneurysm.
Methods: ...
The effects of dexmedetomidine on trauma-induced secondary injury in rat brain
(Taylor & Francis Ltd., 2023)
Background: The objective of this study was to investigate the effect of dexmedetomidine
(Dex), a sedative drug with little or no depressant effect on respiratory centers, on
secondary injury in rat brain tissue by means ...
The effects of dexmedetomidine on abdominal aortic occlusion-induced ovarian injury via oxidative stress and apoptosis
(Karger, 2023)
Ischemia/reperfusion (IR) induced ovarian damage is caused by various diseases such as ovarian torsion, ovarian transplantation, cardiovascular surgery, sepsis, or intra-abdominal surgery. I/R-related oxidative damage can ...
The potential antioxidant effect of N-acetylcysteine on X-ray ionizing radiation-induced pancreas islet cell toxicity
(Elsevier, 2023)
Purpose
Previous research has highlighted the impact of X-ray irradiation-induced organ damage, on cancer patients after radiation therapy. The ionizing radiation-induced oxidative stress causes injury to the pancreatic ...