Ara
Toplam kayıt 83, listelenen: 51-60
Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats
(Sage Publications Ltd, 2018)
Paracetamol (P), one of the most popular and commonly used analgesic and antipyretic agents, causes hepatotoxicity in overdoses. Amlodipine (AML), an L-type calcium channel blocker, has been shown to have anti-inflammatory ...
Effects of gadolinium-based MRI contrast agents on liver tissue
(Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...
The effect of gadolinium-based contrast agents on rat testis
(Wiley, 2018)
Previous studies have reported that repeated administrations of linear gadolinium-based contrast agents lead to their accumulation in the brain and other tissues in individuals with normal renal functions. the purpose of ...
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
(Elsevier, 2019)
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ...
The effects of N-acetylcysteine on radiotherapy-induced small intestinal damage in rats
(Sage Publications Ltd, 2019)
Six million cancer patients worldwide receive radiotherapy, either alone or in combination with other cancer treatments annually. the purpose of this study was to investigate, at the structural and molecular levels, the ...
Effects of infliximab against carbon tetrachloride-induced intestinal injury via lipid peroxidation and apoptosis
(Sage Publications Ltd, 2019)
Carbon tetrachloride (CCL4) is often employed in the production of chlorofluorocarbons, petroleum refining, oil and rubber processing, and laboratory applications. Oral, subcutaneous, and inhalation exposure to CCL4 in ...
Tannic acid exhibits anti-inflammatory effects on formalin-induced paw edema model of inflammation in rats
(Sage Publications Ltd, 2019)
The aim of the study was to determine the relationship between anti-inflammatory effects of the natural polyphenolic compound tannic acid (CAS number: 1401-55-4) and myeloperoxidase (MPO) enzyme activity in paw edema model. ...
The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats
(Springer Heidelberg, 2019)
The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ...
The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology
(Elsevier, 2019)
Background: the most commonly used insecticides and pesticides worldwide are organophosphate compounds, chemicals that irreversibly inhibit the cholinesterase enzyme. Acute intoxication with cholinesterase inhibitors is ...
An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats
(Springer, 2019)
According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ...