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dc.contributor.authorAksoy, Ahsen Nihal
dc.contributor.authorHancı, Burak
dc.contributor.authorBaşkent, Mehmet Furkan
dc.contributor.authorUmutlu, Emine Gül
dc.contributor.authorKumaş, Eda Nur
dc.contributor.authorEmanet, Süleyman Ümit
dc.contributor.authorYalçın, Mehmet Oğuz
dc.contributor.authorDüzyol, Zeynep
dc.contributor.authorTeker, Ayşe Gülşen
dc.contributor.authorYılmaz, Yusuf
dc.date.accessioned2024-03-11T07:58:21Z
dc.date.available2024-03-11T07:58:21Z
dc.date.issued2024en_US
dc.identifier.citationAksoy, A. N., Hanci, B., Baskent, M. F., Umutlu, E. G., Kumas, E. N., Emanet, S. U., Yalcin, M. O., Duzyol, Z., Teker, A. G., & Yilmaz, Y. (2024). Vibration-controlled transient elastography for non-invasive screening of liver fibrosis and steatosis in Turkish patients with psoriasis: A cross-sectional study. Hepatology forum, 5(1), 29–32. https://doi.org/10.14744/hf.2023.2023.0017en_US
dc.identifier.issn1307-5888
dc.identifier.issn2757-7392
dc.identifier.urihttps://doi.org/10.14744/hf.2023.2023.0017
dc.identifier.urihttps://hdl.handle.net/11436/8816
dc.description.abstractBackground and Aim: The prevalence of fibrosis and steatosis in patients with psoriasis, as determined by vibration-controlled transient elastography (VCTE), has not been evaluated in Turkiye to date. The present cross-sectional study aims to present the first systematic screening results, focusing on two primary objectives: 1) establishing the prevalence of fibrosis and steatosis, and 2) identifying independent predictors for liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) values in this patient population. Materials and Methods: Patients were eligible for inclusion if they had a confirmed diagnosis of psoriasis by a qualified dermatologist based on characteristic signs and symptoms and histopathological examination, and had undergone VCTE for LSM and CAP measurements. Results: The diagnosis of severe fibrosis and cirrhosis - identified by LSM values of 10.0-13.9 and >= 14.0 kPa, respectively - was significantly prevalent (7.0% and 10.1%, respectively) among a sizeable cohort of relatively young Turkish patients with psoriasis (n=328; mean age: 49.5 +/- 12.7 years). Additionally, severe steatosis, as diagnosed by VCTE and characterized by a CAP value exceeding 290 dB/m, was identified in up to 43.3% of patients. Although body mass index (BMI) was the only variable found to be an independently associated with LSM, multivariable linear regression analysis failed to identify any statistically independent predictor of CAP values. Conclusion: The prevalence of hepatic fibrosis and steatosis in Turkish patients with psoriasis is far from negligible, with BMI identified as an independent risk factor for fibrosis.en_US
dc.language.isoengen_US
dc.publisherKare Publishingen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFibrosisen_US
dc.subjectPsoriasisen_US
dc.subjectSteatosisen_US
dc.subjectTransient elastographyen_US
dc.subjectVibra-tion-controlleden_US
dc.titleVibration-controlled transient elastography for non-invasive screening of liver fibrosis and steatosis in Turkish patients with A cross-sectionalen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorYılmaz, Yusuf
dc.identifier.doi10.14744/hf.2023.2023.0017en_US
dc.identifier.volume5en_US
dc.identifier.issue1en_US
dc.identifier.startpage29en_US
dc.identifier.endpage32en_US
dc.relation.journalHepatology Forumen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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