Yazar "Bektaş, Hakan" için FEF, Biyoloji Bölümü Koleksiyonu listeleme
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Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus
Bektaş, Hakan; Ceylan, Şule; Demirbaş, Neslihan; Alpay-Karaoğlu, Şengül; Sökmen, Bahar Bilgin (Birkhauser Boston, 2013)2-[6-(Morpholin-4-yl)pyridin-3-ylamino]acetohydrazide (4) was obtained starting from 6-morpholin-4-ylpyridin-3-amine (2) via the formation of ester (3) and then converted to the corresponding Schiff bases (5, 6) with the ... -
Design, synthesis and antimicrobial activities of some azole derivatives
Başoğlu, Serap; Yolal, Meltem; Demirci, Serpil; Demirbaş, Neslihan; Bektaş, Hakan; Karaoğlu, Şengül Alpay (2013)Three new 1,3,4-oxadiazole, 1,3-thiazolidine and 1,2,4-triazole derivatives were obtained starting from furan-2-carbohydrazide. Then, 1,2,4-triazole compound was converted to the corresponding Mannich bases using several ... -
Microwave-assisted synthesis of new benzimidazole derivatives with lipase inhibition activity
Menteşe, Emre; Bektaş, Hakan; Ülker, Serdar; Bekircan, Olcay; Kahveci, Bahittin (Taylor & Francis Ltd, 2014)A practical protocol has been used for the synthesis of benzimidazoles. the reaction of iminoester hydrochlorides of phenylacetic with 4,5-dichloro-1,2-phenylenediamine under microwave irradiation leads to the benzimidazole ... -
Preparation and antimicrobial activity evaluation of some quinoline derivatives containing an azole nucleus
Özyanık, Muhammet; Demirci, Serpil; Bektaş, Hakan; Demirbaş, Neslihan; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay (2012)Quinoline-2-carbohydrazide (2) obtained from quinaldic acid (1) was converted to the corresponding carbothioamide 3 and carboxamide 6 by treatment with benzyliso(thio)cyanate. The basic treatment of 3 and 6 yielded the ... -
Reduction, Mannich reaction, and antimicrobial activity evaluation of some new 1,2,4-triazol-3-one derivatives
Fandaklı, Seda; Başoğlu, Serap; Bektaş, Hakan; Yolal, Meltem; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay (TÜBİTAK, 2012)Ethyl[4-arylmethyleneamino-3-(4-metylphenyl)-5-oxo-4,5-dihydro-1H -1,2,4-triazole-1-yl]acetates (3a-e and 10a-d) were obtained starting from 4-amino-2,4-dihydro-3H -1,2,4-triazol-3-ones (1 and 9) in 2 steps. The treatment ... -
Syntheses and biological activities of new hybrid molecules containing different heterocyclic moieties
Ceylan, Şule; Bektaş, Hakan; Bayrak, Hacer; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay; Ülker, Serdar (Wiley, 2013)4-Aryl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-(thi)oles 5-7, obtained starting from nicotinic acid hydrazide were converted to the corresponding Mannich bases 12-24 by the reaction with several heterocyclic amines in the ... -
Synthesis and antimicrobial activities of some new 1,2,4-triazole derivatives
Bektaş, Hakan; Karaali, Nesrin; Şahin, Deniz; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay; Demirbaş, Neslihan (MDPI, 2010)Some novel 4,5-disubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one (3, 6, 8, 9) derivatives and or 3-(4-methylphenyl)[1,2,4]triazolo[3,4-b][1,3]benzoxazole (5) were synthesized from the reaction of various ester ethoxycarbo ... -
Synthesis and antimicrobial activities of some new 1,2,4-triazole derivatives
Bayrak, Hacer; Demirbaş, Ahmet; Bektaş, Hakan; Karaoğlu, Şengül Alpay; Demirbaş, Neslihan (TUBİTAK, 2010)The synthesis of ethyl [3-(cyanomethyl)-5-alkyl-4H-1,2,4-triazol-4-yl] carbamates (2a-d) was performed starting from ethyl 2-[ethoxy(4-(aryl)methylene] hydrazinecarboxylates (1a, 1b). The treatment of 2a with thiosemicarbazide ... -
Synthesis and antimicrobial activities of some new biheterocyclic compounds containing 1, 2, 4-triazol-3-one and 1, 3, 4-thiadiazole moieties
Bektaş, Hakan; Demirbaş, Ahmet; Demirbaş, Neslihan; Bayrak, Hacer; Karaoğlu, Şengül Alpay (TÜBİTAK, 2010)2-(4-Amino-3-(4-chlorophenyl)-5-oxo-4, 5-dihydro-1 H-1, 2, 4-triazol-1-yl)-N'-[(2, 6 dihalogenophenyl)-methylene]acetohydrazides (3a, b) was obtained via the formation of 2-(4-amino-3-(4-chlorophenyl)-5-oxo-4, 5-dihydro-1 ... -
Synthesis and biological activity studies of new hybrid molecules containing tryptamine moiety
Bektaş, Hakan; Demirbaş, Ahmet; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Springer, 2012)The synthesis of N?-(4-substitutedphenylsulfonyl)-2-{4-[2-(1H-indol- yl)ethyl]-3-(4-chlorobenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl} acetohydrazides (3a-c), 2-{4-[2-(1H-indol-3-yl)ethyl]-3-(4-chlorobenzyl)-5-oxo- ... -
Synthesis of eperezolid-like molecules and evaluation of their antimicrobial activities
Yolal, Meltem; Başoğlu, Serap; Bektaş, Hakan; Demirci, Serpil; Karaoğlu, Şengül Alpay; Demirbaş, Ahmet (Springer Link, 2012)3-Fluoro-4-(4-phenylpiperazin-l-yl)aniline (II) prepared from 3,4-difluoro nitrobenzene was converted to the corresponding Schiff bases (III) and (IV) by treatment with 4-methoxybenzaldehyde and indol-3-carbaldehyde, ... -
Synthesis of some new biheterocyclic triazole derivatives and evaluation of their antimicrobial activity
Bektaş, Hakan; Demirbaş, Ahmet; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (TÜBİTAK, 2010)2-{3-(4-Substitutedbenzyl)-4-[2-(1H-indol-3-yl)ethyl]-5-oxo-4, 5-dihydro-1H-1,2,4-triazol-1-yl}-N' -(arylmethylene) acetohydrazides (5a-g), 4-amino-2-{3-(4-substitutedbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1- yl}-N' ...