Ara
Toplam kayıt 27, listelenen: 21-27
Synthesis and in vitro urease inhibition of some novel benzimidazole-based hydrazones
(Wiley, 2019)
A novel series of N '-(substituted benzylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides and N '-(1-(substituted phenyl)ethylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides were ...
Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities
(Academic Press Inc Elsevier Science, 2019)
A new series of quinazolinone derivatives containing triazole, thiadiazole, thiosemicarbazide functionalities was synthesized and then screened for their in vitro urease inhibition properties. Most of the compounds showed ...
Chalcone-based dipolar cycloaddition of novel heteroaromatic compounds: Their anticancer examination
(Elsevier, 2023)
In this study, new chalcone-isoxazole-based hybrid derivatives (12, 13, 18, and 21) and chalcone-triazole hybrid molecules (26) were synthesized using the click chemistry approach. Among these hybrid molecules, 12, 13, 21, ...
New pyrimidine-N-β-D-glucosides: synthesis, biological evaluation, and molecular docking investigations
(Scientific Technical Research Council Turkey, TÜBİTAK, 2023)
In this study, syntheses of new pyrimidine-coupled N-beta-glucosides and tetra-O-acetyl derivatives were carried out. All glycoconjugates were investigated in comparison with known chemotherapeutic agents in terms of their ...
Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
(Wiley, 2023)
This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ...
Stereo- and Regio-selective benzo- and Benzohalo-conduritols: Anti-diabetes & anti-tumor activity investigation, kinetic and molecular docking studies
(Elsevier, 2023)
In this study, benzoconduritols, benzohalogenoconduritol, and benzodihalogenoconduritols with conduritol-A and –C structures from oxo-norbornene derivative endo-10 b, exo-11 b cleavaged by Lewis acids (BBr3, BCl3, BF3· ...
Imidazole-thiadiazole hybrids: A multitarget de novo drug design approach, in vitro evaluation, ADME/T, and in silico studies
(Wiley, 2024)
A library of imidazole-thiadiazole compounds (1–24) was synthesized to explore their therapeutic applications. The compounds were subjected to meticulous in vitro evaluation against α-glucosidase, α-amylase, acetylcholinesterase ...