Yazar "Baltaş, Nimet" için listeleme
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Synthesis and pancreatic lipase inhibitory activities of some 1,2,4-triazol-5(3)-one derivatives
Özdemir, Yusuf; Bekircan, Olcay; Baltaş, Nimet; Menteşe, Emre (Wiley, 2020)In this study, starting from 4-amino-5-(4-chlorobenzyl)-2,4-dihydro-3H-1,2,4-triazole-3-one (1), the 4-Amino-5-(4-chlorobenzyl)-2-undecyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) was first synthesized and this compound was ... -
Synthesis and urease inhibition study of some new quinazolinone derivatives bearing triazole, thiadiazole, and piperazine moiety
Karaali, Nesrin; Menteşe, Meltem; Baltaş, Nimet; Menteşe, Emre (Wiley, 2018)A new series of 2,3-disubstituted quinazolin-4(3H)-one derivatives bearing triazole and thiadiazole nucleus has been synthesized and then screened for their urease inhibition properties. All synthesized compounds showed ... -
Synthesis of benzimidazoles containing piperazine ring as potential therapeutic agents against diabetes mellitus and antioxidant activities
Özil, Musa; Khan, Khalid Mohammed; Baltaş, Nimet; Wadood, Abdul; Samad, Abdus; Kahveci, Bahittin (Elsevier, 2024)We synthesized a novel 6-(4-substitue-piperazin-1-yl)-2-aryl-1H-benzimidazole derivatives starting from 5-(4-substitue-piperazin-1-yl)-2-nitroaniline with different aldehydes. A quick "onepot" nitro reductive cyclization ... -
Synthesis of new fluorine-containing 1,2,4-triazole-5-on derivatives with their anti-urease, anti-xanthine oxidase and antıoxidant activities
Bekircan, Olcay; Baltaş, Nimet; Menteşe, Emre; Gültekin, Ergün (Editura Acad Romane, 2016)Acetohydrazide derivatives (3a, b) were obtained starting from 3-(2 or 4-fluorobenzyl)-4-amino-4,5-dihydro-1H-1,2,4-triazole-5-one (la, b) by two steps. Compounds 3a, b were converted to the corresponding methylideneacetohydrazide ... -
Synthesis of novel tetra-substituted benzimidazole compounds containing certain heterostructures with antioxidant and anti-urease activities
Karaali, Nesrin; Aydın, Serdar; Baltaş, Nimet; Menteşe, Emre (Wiley, 2020)A new series of 5,6-dimethyl-2-phenyl-1H-benzimidazole derivatives was synthesized. the antioxidant activities of the synthesized compounds were determined according to the cupric reducing antioxidant capacity (CUPRAC), ... -
Synthesis of novel thiosemicarbazone derivatives as antidiabetic agent with enzyme kinetic studies and antioxidant activity
Tok, Fatih; Küçükal, Bahar; Baltaş, Nimet; Tatar Yılmaz, Gizem; Koçyiğit Kaymakçıoğlu, Bedia (Taylor & Francis Ltd., 2022)Novel thiosemicarbazone derivatives were synthesized via condensation reactions between the corresponding thiosemicarbazides and 4-(methylsulfonyl)acetophenone. The chemical structures of all compounds were elucidated by ... -
Synthesis of quinazolinone derivatives containing an acyl hydrazone skeleton as potent anti-urease agents enzyme kinetic studies and anti-oxidant properties
Baltaş, Nimet (Sage Publications, 2022)This paper covers the synthesis, in vitro urease inhibition, enzyme kinetic parameters, and anti-oxidant studies of a novel series of quinazolinone derivatives containing an acyl hydrazone skeleton. Compounds 3a, 3b, 5a, ... -
Synthesis of some new benzimidazole derivatives with their antioxidant activities
Usta, Asu; Yılmaz, Fatih; Kapucu, Gülbahar; Baltaş, Nimet; Menteşe, Emre (Bentham Science Publ Ltd, 2015)In this paper, some benzimidazole derivatives containing salicyl, oxadiazole, thiosemicarbazide and 1, 2, 4-triazole moieties have been synthesized and screened their antioxidant activities screened. Antioxidant activities ... -
Synthesis of some novel pyrazoline and pyrazole derivatives as potential in vitro anti-xanthine oxidase and antioxidant activities
Usta, Asu; Baltaş, Nimet; Özkan, Mahmut (Editura Acad Romane, 2018)2-Pyrazolines and 2-pyrazole, electron-rich nitrogen containing heterocyclic systems, play an important role in several biological and pharmacological activities. in this paper, we report the synthesis of novel ... -
Synthesis of some novel quinazolin-4(3H)-one hybrid molecules as potent urease inhibitors
Menteşe, Emre; Akyüz, Gülay; Yılmaz, Fatih; Baltaş, Nimet; Emirik, Mustafa (Wiley-V C H Verlag Gmbh, 2018)A new series of quinazolinone hybrid molecules containing coumarin, furan, 1,2,4-triazole and 1,2,4-thiadiazole rings was designed, synthesized, and screened for their urease inhibition activities. All newly synthesized ... -
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
Menteşe, Emre; Baltaş, Nimet; Emirik, Mustafa (Academic Press Inc Elsevier Science, 2020)In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ... -
Synthesis, antibacterial and antioxidant activities of some new nsubstituted azachalcone, schiff base and pyrazole derivatives
Çalışkan, Nedime; Usta, Asu; Beriş, Fatih Şaban; Baltaş, Nimet; Çelik, Efsun (Bentham Science Publ Ltd, 2020)Pyrazoles, Schiff bases and the quaternary ammonium compounds (QAC) such as N-alkyl substituted azachalcones are the important group of chemical individuals with widespread usage in many fields of science. in particular, ... -
Synthesis, biological evaluation and in silico studies of new pyrazoline derivatives bearing benzo[d]thiazol-2(3H)-one moiety as potential urease inhibitors
Tok, Fatih; Baltaş, Nimet; Tatar, Gizem; Koçyiğiy Kaymakçıoğlu, Bedia (Wiley, 2022)Novel pyrazoline derivatives containing benzo[d]thiazol-2(3H)-one moiety were synthesized and screened for their inhibitory properties against urease, a clinically important metabolic enzyme. In vitro enzyme inhibition ... -
Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities
Menteşe, Emre; Akyüz, Gülay; Emirik, Mustafa; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2019)A new series of quinazolinone derivatives containing triazole, thiadiazole, thiosemicarbazide functionalities was synthesized and then screened for their in vitro urease inhibition properties. Most of the compounds showed ... -
Urease and acetylcholinesterase enzyme inhibitor novel phthalonitrile azo compounds
Kantar, Cihan; Baltaş, Nimet; Dereci, Oğuz Kağan; Şaşmaz, Selami (Scientific Publishers, 2022)Based on the relationship between Helicobacter pylori and Alzehimer's disease, new azo phthalonitrile compounds containing different amino pyridines have been synthesized. These compounds can inhibit both Urease and ... -
Α-glucosidase and α-amylase inhibition of some ethanolic propolis samples
Baltaş, Nimet (Bursa Uludag University, 2021)Propolis is a natural product, and it is of a great interest due to the possible uses of non-synthetic supplements in improving metabolic disorders. To support this claim, the current study was designed and presented. In ...