Yazar "Arpa, Medeni" için listeleme
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Is netrin-1 deficiency responsible for inflammation and systemic diseases related to pseudoexfoliation?
Okutucu, Murat; Fındık, Hüseyin; Aslan, Mehmet Gökhan; Arpa, Medeni (Lippincott Williams & Wilkins, 2020)Precis: Serum netrin-1 levels are significantly lower in patients with pseudoexfoliation syndrome (PES) and pseudoexfoliative glaucoma (PEG) compared with the control group. Purpose: To investigate serum netrin-1 levels ... -
Neovasküler yaşa bağlı makula dejenerasyonlu olgularda serum vasküler endotelyal büyüme faktörü ve netrin-1 düzeyinin değerlendirilmesi: olgu kontrol çalışması
Okutucu, Murat; Fındık, Hüseyin; Uzun, Feyzahan; Aslan, Mehmet Gökhan; Arpa, Medeni (Türkiye Klinikleri Yayınevi, 2022)Amaç: Bu çalışmanın amacı, neovasküler yaşa bağlı makula dejenerasyonu (n-YBMD) hastalarında serum vasküler endotelyal büyüme faktörü [vascular endothelial growth factor (VEGF)] ve netrin-1 düzeyini sağlıklı kontrol grubu ... -
Neutrophil gelatinase-associated lipocalin as a potential biomarker for pulmonary thromboembolism
Özyurt, Songül; Karataş, Mevlüt; Arpa, Medeni; Kara, Bilge Yılmaz; Duman, Hakan; Memoğlu, Melek; Şahin, Ünal (Walter de Gruyter Gmbh, 2020)Objective: Pulmonary thromboembolism (PTE) is a clinical condition that can be lethal unless promptly diagnosed and treated. the objective was to evaluate the significance of scrum neutrophil gelatinase-associated lipocalin ... -
Orta Düzey B12 Vitamini Değerlerinde Holotranskobalamin Düzeyleri
Kırbaş, Aynur; Arpa, Medeni; Cüre, Medine Cumhur; Topaloğlu, Hacer Bilgin; Yaprak, Ebru; Baykan, Özgür (2016)Amaç: B12 vitamini, vücutta önemli fonksiyonlar üstlenmektedir. Eksikliğinde pek çok hematolojik ve nörolojik bozukluklar ile kendini gösterebilmektedir. Erken dönemde tedaviye başlanmadığında ise bu nörolojik bozukluklar ... -
Oxidative stress and the importance of H. pylori eradication in patients with functional dyspepsia
Ebik, Berat; Aslan, Nihat; Ekin, Nazım; Bacaksız, Ferhat; Arpa, Medeni; Neşelioğlu, Salim; Erel, Özcan; Uçmak, Feyzullah (2022)Background: To investigage the thiol and disulphide levels in Helicobacter pylori-positive patients with non-ulcer dyspepsia and investigate the change in these levels with eradication therapy. Methods: This is a prospective ... -
PET-CT and MR imaging in the management of axillary nodes in early stage breast cancer
Baran, Mehmet Tarık; Gündoğdu, Hasan; Demiral, Gökhan; Kupik, Osman; Arpa, Medeni; Pergel, Ahmet (Coll Physicians & Surgeons Pakistan, 2020)Objective: To discriminate between malignant or benign axillary lymph nodes in breast cancer using MRI, PET-CT, and sentinel lymph node biopsy. Study Design: Observational study. Place and Duration of Study: Department of ... -
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway
Öztürk, Aykut; Topçu, Atilla; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Yılmaz, Eda Kutlu (Wiley, 2022)Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ... -
The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis
Yıldız, İlknur Esen; Topçu, Atilla; Bahçeci, İlkay; Arpa, Medeni; Tümkaya, Levent; Mercantepe, Tolga; Batçık, Şule; Yıldız, Yasin (Pergamon-Elsevier Science Ltd., 2021)Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ... -
Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats
Rakıcı, Sema Yılmaz; Tümkaya, Levent; Erdivanlı, Özlem Çelebi; Yazıcı, Ufuk; Dursun, Engin; Arpa, Medeni; Mercantepe, Tolga (Taylor & Francis Ltd, 2019)Purpose: We investigated the radioprotective effect of endogenous melatonin release at different times associated with the circadian rhythm on head and neck radiotherapy. Materials and methods: Two groups of animals were ... -
Relationship between galectin-3 level and disease activity in ankylosing spondylitis patients
Devrimsel, Gül; Arpa, Medeni; Beyazal, Münevver Serdaroğlu (Springer, 2023)Background and aimsAnkylosing spondylitis (AS) is a chronic inflammatory disease that chiefly affects the sacroiliac joints and the spine. Galectin-3, a chimera-type member of the galectin family, binds glycoconjugates ... -
The relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients undergoing elective transurethral prostate resection surgery with spinal anesthesia
Kazancıoğlu, Leyla; Batçık, Şule; Arpa, Medeni; Kazdal, Hızır; Koyuncu, Tolga; Bilgin, H.; Erel, Özcan (2023)Abstract. – OBJECTIVE: We aimed to investigate the relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients scheduled for elective transurethral prostate resection surgery ... -
The relationship of serum asymmetric dimethylarginine concentrations and lung involvement in patients with COVID-19 infection
Emlek, Nadir; Yılmaz, Ahmet Seyda; Ergül, Elif; Gündoğdu, Hasan; Arpa, Medeni; Koç, Haldun; Öztürk, Muhammet; Aydın, Cihan (2021)Aim: COVID-19 infections the tissue through angiotensin converting enzyme 2 receptor, which is also expressed on endothelial cells. Endothelial dysfunction may be associated with lung involvement. Asymmetric dimethylarginine ... -
Serum 25-hydroxy vitamin D, vitamin B12, and folic acid levels in progressive and nonprogressive keratoconus
Aslan, Mehmet Gökhan; Fındık, Hüseyin; Okutucu, Murat; Aydın, Emre; Oruç, Yavuz; Arpa, Medeni; Uzun, Feyzahan (Lippincott Williams & Wilkins, 2021)Purpose: To evaluate the serum 25-hydroxy vitamin D, vitamin B12, and folic acid (FA) levels in progressive and nonprogressive patients with keratoconus (KCN). Methods: Fifty-five patients with KCN (28 progressive and 27 ... -
Total thiol can contribute to differentiating prostate cancer from BPH: Prostate Thiol Index as a new player
Arpa, Medeni; Şen, Bayram; Eren, Hüseyin; Uzun, Hakkı; Okcu, Oğuzhan; Erel, Özcan (Wiley, 2021)To assess the distinctiveness of serum native thiol (NT), total thiol (TT) and disulfide (SS) levels in PCa patients, we created a new parameter, prostate thiol index (PTI) [tPSA (TTxPVxAge) (-1/2)]. We determined the ... -
Tumor Budding is a reliable predictor for death and metastasis in invasive ductal breast cancer and correlates with other prognostic clinicopathological parameters
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Arpa, Medeni; Bedir, Recep (Elsevier, 2021)Background and objective: Breast cancers are the most common type of cancer and the most common cause of mortality in women worldwide. Different prognostic factors are the subject of research to differentiate the prognosis ... -
What does the procalcitonin level tell us in patients with acute pancreatitis?
Ebik, Berat; Kaçmaz, Hüseyin; Tuncel, Elif Tuğba; Arpa, Medeni; Uçmak, Feyzullah; Kaya, Muhsin (College of Physicians and Surgeons Pakistan, 2022)Objective: To determine the factors affecting the procalcitonin level, and its association with the severity of pancreatitis in patients with acute pancreatitis (AP). Study Design: Cross-sectional analytical study. Place ...