Yazar "Karaoğlu, Şengül Alpay" için listeleme
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Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids
Cebeci, Yıldız Uygun; Ceylan, Şule; Karaoğlu, Şengül Alpay (Elsevier, 2022)In the present study, a series of new indole-3-carbaldehyde embedded triazole derivatives have been synthesized. 4-{[(1E)-1H-indol-3-ylmethylidene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) were converted to ... -
Conventional and microwave-assisted synthesis of novel 1,2,4-triazole derivatives containing tryptamine skeleton and evaluation of antimicrobial activity
Cebeci, Yıldız Uygun; Ceylan, Şule; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Bentham Science Publishing, 2021)1,2,4-Triazole-3-one (3) obtained from tryptamine was transformed to the corresponding carbox(thio)amides via several steps (6a-d). Their reaction with sodium hydroxide performed the 1,2,4triazole derivatives (7a-d). ... -
Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities
Bayrak, Hacer; Demirbaş, Ahmet; Demirbas, Neslihan; Karaoğlu, Şengül Alpay (Elsevier, 2010)Acetohydrazide derivative containing both antipyrine and triazole nuclei (5) was obtained starting from ethyl hydrazinecarboxylate derivative (2) and 4-aminoantipyrine (1) by three steps. The treatment of compound 5 with ... -
Çay Üretim Aşamalarından İzole Edilen Mayaların Tanımlanması
Çay Dünya'da sudan sonra tüketilen en önemli içecektir. Bu çalışmada, çay yapraklarının tarladan fabrikaya gelişi ile başlayan çay işleme aşamalarından ve poşetlenen siyah çaydan izole edilen mayaların tanımlanması ve bir ... -
Design and microwave-assisted synthesis of a novel Mannich base and conazole derivatives and their biological assessment
Cebeci, Yıldız Uygun; Karaoğlu, Şengül Alpay (Walter de Gruyter, 2021)4-Amino-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (1) was converted to the corresponding Schiff base (2) by treatment with salicylaldehyde. 1,2,4-Triazoles were then converted to the corresponding Mannich bases containing ... -
Design and microwave-assisted synthesis of a novel Mannich base and conazole derivatives and their biological assessment
Cebeci, Yıldız Uygun; Karaoğlu, Şengül Alpay (Walter de Gruyter, 2021)4-Amino-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (1) was converted to the corresponding Schiff base (2) by treatment with salicylaldehyde. 1,2,4-Triazoles were then converted to the corresponding Mannich bases containing ... -
Design and synthesis of new 1,2,4-triazole deriaties containing morpholine moiety as antimicrobial agents
Şahin, Deniz; Bayrak, Hacer; Demirbaş, Ahmet; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (TÜBİTAK, 2012)2-Morpholine-4ylethyl-3H -1,2,4-triazole-3-ones (2a, 2b) were obtained from the condensation between the corresponding ethoxycarbonylhydrazones and 2-morpholinoethanamine. 2a was conerted to acetohydrazide (4) ia the ... -
Design and synthesis of some azole derivatives as potential antimicrobial agents
Şahin, Deniz; Bayrak, Hacer; Demirbaş, Ahmet; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Birkhauser Boston, 2012)Syntheses of 1,2,4-triazol-3-ones, 4a, 4b, and 5 were performed starting from ester ethoxycarbonylhyd-razones (1a, 1b) that were reported earlier. The treatment of triazole derivatives, 4a, 4b, and 5 with several sulfonyl ... -
Design, synthesis and antimicrobial activities of some azole derivatives
Başoğlu, Serap; Yolal, Meltem; Demirci, Serpil; Demirbaş, Neslihan; Bektaş, Hakan; Karaoğlu, Şengül Alpay (2013)Three new 1,3,4-oxadiazole, 1,3-thiazolidine and 1,2,4-triazole derivatives were obtained starting from furan-2-carbohydrazide. Then, 1,2,4-triazole compound was converted to the corresponding Mannich bases using several ... -
Design, synthesis and molecular modeling studies on novel moxifloxacin derivatives as potential antibacterial and antituberculosis agents
Türe, Aslı; Kulabaş, Necla; Dingiş, Serap İpek; Birgül, Kaan; Bozdeveci, Arif; Karaoğlu, Şengül Alpay; Krishna, Vagolu Siva; Sriram, Dharmarajan; Küçükgüzel, İlkay (Academic Press Inc Elsevier Science, 2019)Twenty-one novel alkyl/acyl/sulfonyl substituted fluoroquinolone derivatives were designed, synthesized and evaluated for their anti-tuberculosis and antibacterial activity. the targeted compounds were synthesized by the ... -
Determination of biocontrol properties of two local trichoderma isolates
Bozdeveci, Arif; Karaoğlu, Şengül Alpay (Springer, 2023)Many plant pathogens, especially Rhizoctonia solani, Pythium spp. and Alternaria spp. can seriously affect seedling growth and crop production. Trichoderma is recognized as a suitable biological plant protection product ... -
Determination of bioremediation potentials and plant growth-promoting properties of bacillus species isolated from the rhizosphere of dactylorhiza urvilleana
Üreyen Esertaş, Ülkü Zeynep; Bozdeveci, Arif; Uzunalioğlu, Emel; Karaoğlu, Şengül Alpay (Namik Kemal University - Agricultural Faculty, 2023)Industrial activities have been one of the biggest factors of environmental destruction by affecting natural resources for decades. Heavy metals, which are one of the greatest dangers especially for the biosphere, can be ... -
Determination of bioremediation properties of soil-borne Bacillus sp. 5O5Y11 and its effect on the development of Zea mays in the presence of copper
Esertaş, Ülkü Zeynep Üreyen; Uzunalioğlu, Emel; Güzer, Şule; Bozdeveci, Arif; Karaoğlu, Şengül Alpay (Springer, 2020)Today, industrial activities lead to the accumulation of heavy metals in the soil, water, and air due to mine deposits and operations, fertilizers, and drugs used in agriculture, and urban wastes. Using microorganism ... -
Determination of phenolic contents by HPLC, and antioxidant, antimicrobial, antityrosinase, and anticholinesterase activities of psephellus huber-morathii
Korkmaz, Nuriye; Şener, Sıla Özlem; Baltürk, Nuray; Kanbolat, Şeyda; Badem, Merve; Aliyazıcıoğlu, Rezzan; Özgen, Ufuk; Kandemir, Ali; Karaoğlu, Şengül Alpay (Sciencedomain Int, 2019)The goal of our study was to examine of antioxidant, antimicrobial, anticholinesterase activities, and phenolic composition of Psephellus huber-morathii. the antioxidant activities of extracts have been assessed by Ferric ... -
Determination of The Microflora, Quality and Mineral Substance Contents of Black Tea (Camellia sinensis)
The black tea is produced from different varieties of Camellia sinensis (Linneaus) O. Kutzeafter withering, rolling, fermantation, drying, classification and packing stages of green tea leaves, buds and the parts of fresh ... -
DNA binding, antioxidant and antimicrobial activities of homo- and heteronuclear copper(II) and nickel(II) complexes with new oxime-type ligands
Çolak, Ahmet; Terzi, Ülkü; Çöl, Melek; Karaoğlu, Şengül Alpay; Karaböcek, Serdar; Küçükdumlu, Aslıgül; Ayaz, Faik Ahmet (Elsevier, 2010)Some homo- and heteronuclear Cu(II) and Ni(II) complexes of new oxime-type ligands were tested against several pathogenic microorganisms to assess their antimicrobial potentials. The antimicrobial activities of complexes ... -
Do different substrates affect antioxidant properties and antimicrobial activity of Pleurotus ostreatus?
The aim of this study is to determine the effect of growing substrates on the antioxidant properties and antimicrobial activities of Pleurotus ostreatus (Jacq.) P. Kumm. In the study, growing substrates were prepared ... -
Ecofriendly solventless synthesis and reduction reaction of some triazole compounds and evaluation of their antimicrobial activity
Özil, Musa; Menteşe, Emre; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Taylor & Francis Inc, 2013)A number of triazole-3-one compounds have been synthesized, and reduction of the carbonyl group in the molecule has been carried out to give a corresponding hydroxyl group that possesses asymmetric carbon atom in good ... -
The effect of disinfection methods on C. albicans in three types of denture base materials
Akyıldız, Gülşah; Duymuş, Zeynep Yeşil; Karaoğlu, Şengül Alpay; Bozdeveci, Arif (Revista Chimie SRL., 2023)This study aimed to evaluate the efficacy of disinfectant solutions on Candida albicans (C. albicans) for different types of denture materials. A total of 144 specimens (10x10x2 mm) were obtained from three different ... -
Effect of propolis in gastric disorders: inhibition studies on the growth of Helicobacter pylori and production of its urease
Baltaş, Nimet; Karaoğlu, Şengül Alpay; Tarakcı, Cemre; Kolaylı, Sevgi (Taylor & Francis Ltd, 2016)There is considerable interest in alternative approaches to inhibit Helicobacter pylori (H. pylori) and thus treat many stomach diseases. Propolis is a pharmaceutical mixture containing many natural bioactive substances. ...