The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease

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2025Author
Eslam, MohammedFan, Jian-Gao
Yu, Ming-Lung
Wong, Vincent Wai-Sun
Cua, Ian Homer
Liu, Chun-Jen
Tanwandee, Tawesak
Gani, Rino
Seto, Wai-Kay
Alam, Shahinul
Young, Dan Yock
Hamid, Saeed
Zheng, Ming-Hua
Kawaguchi, Takumi
Chan, Wah-Kheong
Payawal, Diana
Tan, Soek-Siam
Goh, George Boon-bee
Strasser, Simone I.
Viet, Hang Dao
Kao, Jia-Horng
Kim, Won
Kim, Seung Up
Keating, Shelley E.
Yılmaz, Yusuf
Kamani, Lubna
Wang, Chia-Chi
Fouad, Yasser
Abbas, Zaigham
Treeprasertsuk, Sombat
Thanapirom, Kessarin
Al Mahtab, Mamun
Lkhagvaa, Undram
Baatarkhuu, Oidov
Choudhury, Ashok Kumar
Stedman, Catherine A. M.
Chowdhury, Abhijit
Dökmeci, A Kadir
Wang, Fu-Sheng
Lin, Han-Chieh
Huang, Jee-Fu
Howell, Jess
Jia, Jidong
Alboraie, Mohamed
Roberts, Stuart K.
Yoneda, Masato
Ghazinian, Hasmik
Mirijanyan, Aram
Nan, Yuemin
Lesmana, Cosmas Rinaldi Adithya
Adams, Leon A.
Shiha, Gamal
Kumar, Manoj
Örmeci, Necati
Wei, Lai
Lau, George
Omata, Masao
Sarin, Shiv K.
George, Jacob
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Eslam, M., Fan, J. G., Yu, M. L., Wong, V. W., Cua, I. H., Liu, C. J., Tanwandee, T., Gani, R., Seto, W. K., Alam, S., Young, D. Y., Hamid, S., Zheng, M. H., Kawaguchi, T., Chan, W. K., Payawal, D., Tan, S. S., Goh, G. B., Strasser, S. I., Viet, H. D., … George, J. (2025). The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease. Hepatology international, 19(2), 261–301. https://doi.org/10.1007/s12072-024-10774-3Abstract
Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused on MAFLD. The guidelines cover various aspects of the disease, such as its epidemiology, diagnosis, screening, assessment, and treatment. The guidelines aim to advance clinical practice, knowledge, and research on MAFLD, particularly in special groups. The guidelines are designed to advance clinical practice, to provide evidence-based recommendations to assist healthcare stakeholders in decision-making and to improve patient care and disease awareness. The guidelines take into account the burden of clinical management for the healthcare sector.