dc.contributor.author | Tunç, Süphan | |
dc.contributor.author | Kesiktaş, Erol | |
dc.contributor.author | Yılmaz, Yeliz | |
dc.contributor.author | Acıkalın, Arbil | |
dc.contributor.author | Oran, Gökçen | |
dc.contributor.author | Yavuz, Metin | |
dc.contributor.author | Gencel, Eyüphan | |
dc.contributor.author | Eser, Cengiz | |
dc.date.accessioned | 2020-12-19T19:50:21Z | |
dc.date.available | 2020-12-19T19:50:21Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Tunç, S., Kesiktas, E., Yilmaz, Y., Açikalin, A., Oran, G., Yavuz, M., Gencel, E., & Eser, C. (2016). Assessing the effects of melatonin and N-acetylcysteine on the McFarlane flap using a rat model. Plastic Surgery, 24(3), 204–208. https://doi.org/10.1177/229255031602400302 | en_US |
dc.identifier.issn | 2292-5503 | |
dc.identifier.issn | 2292-5511 | |
dc.identifier.uri | https://hdl.handle.net/11436/2419 | |
dc.description | gencel, eyuphan/0000-0003-1929-3838; eser, cengiz/0000-0002-1208-717X; Acikalin, Arbil/0000-0003-1592-2887; YILMAZ, Yeliz/0000-0003-1811-122X | en_US |
dc.description | WOS: 000383781900010 | en_US |
dc.description | PubMed: 28439512 | en_US |
dc.description.abstract | OBJECTIVE: To determine the effects of N-acetylcysteine (NAC) and melatonin, alone and in combination, on McFarlane flap viability in a rat model. METHODS: Forty Wistar rats were divided into four groups and received daily intraperitoneal injections for one week before surgery: control (sham [n=10]); melatonin (n=10); NAC (n=10); and NAC+ melatonin (n=10). One week after surgery, the experiment was terminated and photographs were taken for topographic studies. A transillumination study was performed to observe vascularization in the flaps and biopsies were obtained for histopathological studies. RESULTS: Flap viability was significantly greater in the antioxidant-(ie, NAC and melatonin) treated groups compared with the control group; however, there were no significant differences among the groups that received antioxidants. CONCLUSIONS: Melatonin and NAC are important antioxidants that can be used alone or in combination to increase flap viability and prevent distal necrosis in rats. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Sage Publications Inc | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | McFarlane flap | en_US |
dc.subject | Melatonin | en_US |
dc.subject | NAC | en_US |
dc.subject | N-acetylcysteine | en_US |
dc.title | Assessing the effects of melatonin and N-acetylcysteine on the McFarlane flap using a rat model | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Yılmaz, Yeliz | |
dc.identifier.volume | 24 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 204 | en_US |
dc.identifier.endpage | 208 | en_US |
dc.relation.journal | Plastic Surgery | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |