Biosynthetic versus polytetrafluoroethylene graft in extra-anatomical bypass surgery of takayasu arteritis patients with supra-aortic disease

Abstract

Introduction: To evaluate treatment outcomes of patients diagnosed with Takayasu arteritis (TA), who underwent extra-anatomical bypass surgery using biosynthetic grafts. Methods: This retrospective study included 12 TA patients considered eligible for surgical revascularization between January 2005 and May 2011 from two vascular surgical units in Turkey. Control group consisted of 12 peripheral arterial disease patients who underwent supra-aortic extra-anatomical bypass surgery using polytetrafluoroethylene (PTFE) graft. Preoperatively, all patients underwent Doppler ultrasound and arteriography. Patients were examined every 3 months for clinical findings after monthly follow-up during the first 6 months, first, second and third year controls. Graft patencies were evaluated by Doppler ultrasound at each visit. Results: the mean age was 38.6 +/- 4.2 years and the mean follow-up time was 37.9 +/- 6.9 months for the study group. in Biosynthetic Group, subclavian-subclavian (n = 2), axillo-axillary (n = 9) and carotico-subclavian (n = 1) bypass operations were performed. in PTFE group, subclavian-subclavian (n = 3), axillo-axillary (n = 7), subclavian-left ulnar (n = 1), subclavian-distal brachial (n = 1) bypass operations were performed. Graft occlusion occurred in four patients in PTFE Group during follow-up period. These occlusive lesions were treated successfully according to the routine of each vascular unit. Conclusion: We concluded that in inflammatory diseases like TA, biosynthetic grafts have promising patency, postoperative clinical findings and lower rates of complications requiring reintervention in mid-term.