• Türkçe
    • English
  • English 
    • Türkçe
    • English
  • Login
View Item 
  •   RTEÜ
  • Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
  • WoS İndeksli Yayınlar Koleksiyonu
  • View Item
  •   RTEÜ
  • Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
  • WoS İndeksli Yayınlar Koleksiyonu
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Epicardial adipose tissue thickness and NGAL levels in women with polycystic ovary syndrome

Thumbnail

View/Open

Full Text / Tam Metin (280.5Kb)

Access

info:eu-repo/semantics/openAccess

Date

2014

Author

Şahin, Serap Baydur
Cüre, Medine Cumhur
Uğurlu, Yavuz
Ergül, Elif
Gür, Emine Uslu
Alyıldız, Neşe
Bostan, Mehmet

Metadata

Show full item record

Citation

Sahin, S.B., Cure, M.C., Ugurlu, Y., Ergul, E., Gur, E.U., Alyildiz, N., Bostan, M., (2014). Epicardial adipose tissue thickness and NGAL levels in women with polycystic ovary syndrome. Journal of Ovarian Research, 7, article number 24. https://doi.org/10.1186/1757-2215-7-24

Abstract

Background: Polycystic ovary syndrome (PCOS) is associated with an increased cardiovascular disease (CVD) risk and early atherosclerosis. Epicardial adipose tissue thickness (EATT) is clinically related to subclinical atherosclerosis. in the present study, considering the major role of neutrophil gelatinase-associated lipocalin (NGAL) which is an acute phase protein rapidly releasing upon inflammation and tissue injury, we aimed to evaluate NGAL levels and EATT in PCOS patients and assess their relationship with cardiometabolic factors. Methods: 64 patients with PCOS and 50 age- and body mass index-matched healthy controls were included in the study. We evaluated anthropometric, hormonal and metabolic parameters. EATT was measured by echocardiography above the free wall of the right ventricle. Serum NGAL and high-sensitive C-reactive protein (hsCRP) levels were measured by ELISA. Results: Mean EATT was 0,38 +/-0,16 mm in the PCOS group and 0,34 +/-0,36 mm in the control group (p = 0,144). in the obese PCOS group (n = 44) EAT was thicker compared to the obese control group (n = 41) (p = 0.026). Mean NGAL levels of the patients with PCOS were 101,98 +/-21,53 pg/ml, while mean NGAL levels were 107,40 +/-26,44 pg/ml in the control group (p = 0,228). We found a significant positive correlation between EATT and age, BMI, waist circumference, fasting insulin, HOMA-IR, triglyceride and hsCRP levels in PCOS group. Conclusions: Thickness of the epicardial adipose tissue can be used to follow the risk of CVD development in obese PCOS cases. However serum NGAL levels do not differ in patients with PCOS and control group.

Source

Journal of Ovarian Research

Volume

7

URI

https://doi.org/10.1186/1757-2215-7-24
https://hdl.handle.net/11436/3158

Collections

  • PubMed İndeksli Yayınlar Koleksiyonu [2443]
  • Scopus İndeksli Yayınlar Koleksiyonu [6245]
  • TF, Dahili Tıp Bilimleri Bölümü Koleksiyonu [1624]
  • TF, Temel Tıp Bilimleri Bölümü Koleksiyonu [713]
  • WoS İndeksli Yayınlar Koleksiyonu [5364]



DSpace software copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback
Theme by 
@mire NV
 

 




| Instruction | Guide | Contact |

DSpace@RTEÜ

by OpenAIRE
Advanced Search

sherpa/romeo

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsTypeLanguageDepartmentCategoryPublisherAccess TypeInstitution AuthorThis CollectionBy Issue DateAuthorsTitlesSubjectsTypeLanguageDepartmentCategoryPublisherAccess TypeInstitution Author

My Account

LoginRegister

Statistics

View Google Analytics Statistics

DSpace software copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback
Theme by 
@mire NV
 

 


|| Guide|| Instruction || Library || Recep Tayyip Erdoğan University || OAI-PMH ||

Recep Tayyip Erdoğan University, Rize, Turkey
If you find any errors in content, please contact:

Creative Commons License
Recep Tayyip Erdoğan University Institutional Repository is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported License..

DSpace@RTEÜ:


DSpace 6.2

tarafından İdeal DSpace hizmetleri çerçevesinde özelleştirilerek kurulmuştur.