dc.contributor.author | Şekeryapan, Berrak | |
dc.contributor.author | Öner, Veysi | |
dc.contributor.author | Kırbaş, Aynur | |
dc.contributor.author | Türkyılmaz, Kemal | |
dc.contributor.author | Durmuş, Mustafa | |
dc.date.accessioned | 2020-12-19T20:04:35Z | |
dc.date.available | 2020-12-19T20:04:35Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Sekeryapan, B., Oner, V., Kirbas, A., Turkyilmaz, K., & Durmus, M. (2013). Plasma homocysteine levels in dry eye patients. Cornea, 32(5), e94–e96. https://doi.org/10.1097/ICO.0b013e31826f326b | en_US |
dc.identifier.issn | 0277-3740 | |
dc.identifier.issn | 1536-4798 | |
dc.identifier.uri | https://doi.org/10.1097/ICO.0b013e31826f326b | |
dc.identifier.uri | https://hdl.handle.net/11436/3344 | |
dc.description | WOS: 000317467300009 | en_US |
dc.description | PubMed: 23132455 | en_US |
dc.description.abstract | Purpose: To compare plasma homocysteine levels between patients with dry eye disease and normal control subjects. Methods: Plasma homocysteine (enzyme immunoassay), vitamin B12, and folate levels were determined in 38 patients with dry eye and in 38 controls. Results: Characteristics of the dry eye and control groups were similar. the mean plasma homocysteine level was 16.38 +/- 6.98 mmol/L in the dry eye group and 14.39 +/- 5.11 mu mol/L in the control group (P = 0.10, t test). Hyperhomocysteinemia was present in the 43.9% of the dry eye patients and 33.3% of the controls (P = 0.43, chi(2) test). There were no statistical differences between dry eye and control groups regarding plasma vitamin B12 and folate levels (P = 0.72 and P = 0.69, respectively, t test). Conclusions: Plasma homocysteine levels in dry eye patients may be inadequate to give homocysteine a role in pathogenesis. However, in ocular diseases like glaucoma, plasma homocysteine levels are significantly higher, and associated dry eye disease may cause an additional increase in plasma homocysteine levels. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Lippincott Williams & Wilkins | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Dry eye disease | en_US |
dc.subject | Homocysteine | en_US |
dc.subject | Vitamin B12 | en_US |
dc.subject | Folate | en_US |
dc.title | Plasma homocysteine levels in dry eye patients | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Şekeryapan, Berrak | |
dc.contributor.institutionauthor | Öner, Veysi | |
dc.contributor.institutionauthor | Kırbaş, Aynur | |
dc.contributor.institutionauthor | Türkyılmaz, Kemal | |
dc.contributor.institutionauthor | Durmuş, Mustafa | |
dc.identifier.doi | 10.1097/ICO.0b013e31826f326b | |
dc.identifier.volume | 32 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | E94 | en_US |
dc.identifier.endpage | E96 | en_US |
dc.relation.journal | Cornea | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |