Reversible anorgasmia with topiramate therapy for migraine prophylaxis

Abstract

Topiramate is an effective drug for the prevention of migraine headaches. On occasion, topiramate can be associated with a dose-related anorgasmia. Presented here is an adult case of reversible anorgasmia induced by and possibly attributable to topiramate therapy. Physicians need to be aware of the potential for topiramate to dose related reversible anorgasmia, and should inquire about sexual symptoms of patients. © 2010 Versita Warsaw and Springer-Verlag Berlin Heidelberg.