Evaluation of radiological images of cases operated for nasal polyp

Abstract

Objective: In this study, we aimed to evaluate the differential diagnosis of nasal polyps and infected nasal polyps before the operation with density measurement in paranasal sinus computed tomography examination.

Methods: The study included 129 patients (93 men and 36 women; mean age 41.00 years; range 13 to 82 years) diagnosed as nasal polyps (nasal polyps group) and 26 patients (17 men, 9 women; mean age 42.50 years; range 16 to 74 years) diagnosed as infected nasal polyps. In the preoperative paranasal computed tomography examination, the nasal polyps density of the patients was scored according to the Lund-Mackey system. To measure the volume of inflammatory opacification, the soft tissue density ratio (%) was measured. Neutrophil to lymphocyte ratio, mean platelet volume values, Lund-Mackey system, and soft tissue density ratio scores were statistically compared in all the groups.

Results: The median mean platelet volume value was 9.40 (6.4-12.0) in the nasal polyps group and 10.20 (7.9-12.1) in the infected nasal polyps group with a statistically significant difference (P = .007). There was a significant positive correlation between infected nasal polyps and mean platelet volume (P = .006, r = 0.219**), Lund-Mackey system total, and soft tissue density ratio total (P = .000, r = 0.797**). According to the results of receiver operating curve analysis in patients with infected nasal polyps, sensitivity 61.5% and specificity 60.5% for mean platelet volume (P = .007, area under curve: 0.669 [0.574-0.763]) were found. The cut-off point for mean platelet volume value was > 9.95.

Conclusion: If there is an infection in patients with nasal polyps, surgery should be considered after antibiotic therapy. The use of mean platelet volume as a marker of inflammation in these patients appears to be more reliable than the Lund-Mackey system and soft tissue density ratio scores.