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dc.contributor.authorGezer, Halise Hande
dc.contributor.authorDuruöz, Mehmet Tuncay
dc.contributor.authorNas, Kemal
dc.contributor.authorKılıç, Erkan
dc.contributor.authorSargın, Betül
dc.contributor.authorAcer Kasman, Sevtap
dc.contributor.authorAlkan, Hakan
dc.contributor.authorŞahin, Nilay
dc.contributor.authorCengiz, Gizem
dc.contributor.authorCüzdan, Nihan
dc.contributor.authorAlbayrak Gezer, İlknur
dc.contributor.authorKeskin, Dilek
dc.contributor.authorMülkoğlu, Cevriye
dc.contributor.authorReşorlu, Hatice
dc.contributor.authorSunar, İsmihan
dc.contributor.authorBal, Ajda
dc.contributor.authorKüçükakkaş, Okan
dc.contributor.authorYurdakul, Ozan Volkan
dc.contributor.authorAlkan Melikoğlu, Meltem
dc.contributor.authorBaykul, Merve
dc.contributor.authorAyhan, Fikriye Figen
dc.contributor.authorBodur, Hatice
dc.contributor.authorÇalış, Mustafa
dc.contributor.authorÇapkın, Erhan
dc.contributor.authorDevrimsel, Gül
dc.contributor.authorGök, Kevser
dc.contributor.authorHizmetli, Sami
dc.contributor.authorKamanlı, Ayhan
dc.contributor.authorKeskin, Yaşar
dc.contributor.authorEcesoy, Hilal
dc.contributor.authorKutluk, Öznur
dc.contributor.authorŞen, Nesrin
dc.contributor.authorŞendur, Ömer Faruk
dc.contributor.authorTekeoğlu, İbrahim
dc.contributor.authorTolu, Sena
dc.contributor.authorToprak, Murat
dc.contributor.authorTuncer, Tiraje
dc.date.accessioned2023-01-07T16:41:14Z
dc.date.available2023-01-07T16:41:14Z
dc.date.issued2022en_US
dc.identifier.citationGezer, H. H., Duruöz, M. T., Nas, K., Kılıç, E., Sargın, B., Kasman, S. A., Alkan, H., Şahin, N., Cengiz, G., Cüzdan, N., Gezer, İ. A., Keskin, D., Mülkoğlu, C., Reşorlu, H., Sunar, İ., Bal, A., Küçükakkaş, O., Yurdakul, O. V., Melikoğlu, M. A., Baykul, M., … Tuncer, T. (2022). Inconsistencies of the Disease Activity Assessment Tools for Psoriatic Arthritis: Challenges to Rheumatologists. Joint bone spine, 89(3), 105296. https://doi.org/10.1016/j.jbspin.2021.105296en_US
dc.identifier.issn1297-319X
dc.identifier.urihttps://doi.org/10.1016/j.jbspin.2021.105296
dc.identifier.urihttps://hdl.handle.net/11436/7353
dc.description.abstractObjective: Currently, concerning the evaluation of psoriatic arthritis (PsA), there is no agreement on a standardized composite index for disease activity that includes all relevant domains. The present study sought to assess the rates of remission (REM)/low disease activity (LDA) and disease states [minimal disease activity (MDA), very low disease activity (VLDA)] as defined by diverse activity scales (DAPSA, DAS28-ESR) in an attempt to display discrepancies across these assessment tools for peripheral PsA. Methods: The study involved 758 patients (496 females, 262 males; mean age 47,1 years) with peripheral PsA who were registered to the Turkish League Against Rheumatism (TLAR) Network. The patients were assessed using the DAS28-ESR, DAPSA, MDA, and VLDA. The overall yield of each scale was assessed in identifying REM and LDA. The presence or absence of swollen joints was separately analysed. Results: The median disease duration was 4 years (range 0-44 years). According to DAPSA and DAS28-ESR, REM was achieved in 6.9% and 19.5% of the patients, respectively. The rates of MDA and VLDA were 16% and 2.9%, respectively. Despite the absence of swollen joints, a significant portion of patients were not considered to be in REM (296 (39.1%) patients with DAS28-ESR, 364 (48%) with DAPSA, and 394 (52%) with VLDA). Conclusion: Patients with peripheral PsA may be assigned to diverse disease activity levels when assessed with the DAS28-ESR, DAPSA, MDA and VLDA, which would inevitably have clinical implications. In patients with PsA a holistic approach seems to be necessary which includes other domains apart from joint involvement, such as skin involvement, enthesitis, spinal involvement, and patient-reported outcomes.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComposite indexen_US
dc.subjectDisease activityen_US
dc.subjectPsoriatic arthritisen_US
dc.subjectRemissionen_US
dc.titleInconsistencies of the disease activity assessment tools for psoriatic arthritis: Challenges to rheumatologistsen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorDevrimsel, Gül
dc.identifier.doi10.1016/j.jbspin.2021.105296en_US
dc.identifier.volume89en_US
dc.identifier.issue3en_US
dc.identifier.startpage105296en_US
dc.relation.journalJoint Bone Spineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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