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dc.contributor.authorGündoğdu, Hasan
dc.contributor.authorKupik, Osman
dc.date.accessioned2023-02-23T07:10:17Z
dc.date.available2023-02-23T07:10:17Z
dc.date.issued2021en_US
dc.identifier.citationGündoğdu, H. & Kupik, O. (2021). Comparison of 18F FDG PET / CT, MRI (DWI + DCE) and MRI + 18F FDG PET/CT in thedetection of axillary metastatic lymph nodes in patients with newly diagnosed breast cancer. Experimental Biomedical Research, 4(3), 206-215. http://doi.org/10.30714/j-ebr.2021370075en_US
dc.identifier.issn2618-6454
dc.identifier.urihttp://doi.org/10.30714/j-ebr.2021370075
dc.identifier.urihttps://hdl.handle.net/11436/7688
dc.description.abstractAim: We visually and quantitatively investigated the success of using 2-deoxy-2-[fluorine-18] fluoro-Dglucose integrated with computed tomography ( 18F-FDG PET/CT) and magnetic resonance imaging (MRI) [Dynamic contrast enhancement (DCE) and diffusion weighted imaging (DWI)] separately and together in detecting axillary lymph node metastasis in patients with newly diagnosed breast cancer. Methods: One hundred and thirteen patients who underwent 18F FDG PET/CT were evaluated, 102 patients of these patients had also MRI (DEC + DWI). Primary tumour size (Tsize), SUVmax of primary tumour (SUVmaxT), short diameter of largest axillary lymph node on PET/CT (LnDPET/CT), SUVmax of axillary lymph node (SUVmaxLn), metabolic tumour volume of the primary tumour (MTV), short diameter of largest axillary lymph node on MRI (LnDMRI), the presence of fatty hilum absence and apparent diffusion coefficient (ADC) were evaluated. Results: In visual analysis, sensitivity and specificity values of 18F FDG PET/CT, MRI and MRI+18F FDG PET/CT were 78.85, 94% – 72.27%, 96.15 – 83.87%, 98.04%, respectively. In the quantitative evaluation, ADC≤1.2 x 10-3 mm2 /sec (OR = 6.665, p = 0.001, 95CI%: 2.181–20.370) and LnSUVmax> 2 (OR = 15.2, p<0.001, 95CI%: 4.587–50.376) were independent predictors in detecting axillary lymph node metastasis. Conclusion: LnSUVmax >2 and ADC ≤ 1.2 x 10-3 mm2 /sec can be used as independent predictors of detecting axillary lymph node metastasis in patients with newly diagnosed breast cancer.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast neoplasmsen_US
dc.subjectlymphatic metastasisen_US
dc.subjectFluorodeoxyglucose F18en_US
dc.subjectPET / CTen_US
dc.subjectMRIen_US
dc.titleComparison of 18F FDG PET / CT, MRI (DWI + DCE) and MRI + 18F FDG PET/CT in the detection of axillary metastatic lymph nodes in patients with newly diagnosed breast canceren_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorGündoğdu, Hasan
dc.identifier.doi10.30714/j-ebr.2021370075en_US
dc.identifier.volume4en_US
dc.identifier.issue3en_US
dc.identifier.startpage206en_US
dc.identifier.endpage215en_US
dc.relation.journalExperimental Biomedical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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