dc.contributor.author | Gül, Fethi | |
dc.contributor.author | Kasapoğlu, Umut Sabri | |
dc.contributor.author | Sabaz, Mehmet Süleyman | |
dc.contributor.author | Ay, Pınar | |
dc.contributor.author | Doruk Oktay, Burçin | |
dc.contributor.author | Çalışkan, Gülbahar | |
dc.contributor.author | Demir, Nalan | |
dc.contributor.author | Sayan, İsmet | |
dc.contributor.author | Kabadayı, Feyyaz | |
dc.contributor.author | Altuntaş, Gülsüm | |
dc.contributor.author | Gümüş, Ayça | |
dc.contributor.author | Kırca, Hülya | |
dc.contributor.author | Şanlı, Deniz | |
dc.contributor.author | Acil, Fatma | |
dc.contributor.author | Dedeoğlu, Andaç | |
dc.contributor.author | Ural, Sedef Gülçin | |
dc.contributor.author | Akın Şen, İrem | |
dc.contributor.author | Macit Aydın, Eda | |
dc.contributor.author | Dayanır, Hakan | |
dc.contributor.author | Yelken, Birgül | |
dc.contributor.author | Ceylan, İlkay | |
dc.contributor.author | Aydın, Osman Özcan | |
dc.contributor.author | Eskidemir, Güneş | |
dc.contributor.author | Aytekin, Ahmet | |
dc.contributor.author | Cengiz, Melike | |
dc.contributor.author | Arslan, Ülkü | |
dc.contributor.author | Akdağ, Devrim | |
dc.contributor.author | Alay, Gülçin Hilal | |
dc.contributor.author | Tekin, Esra | |
dc.contributor.author | Yarar, Volkan | |
dc.contributor.author | Saraçoğlu, Kemal Tolga | |
dc.contributor.author | Gök, Funda | |
dc.contributor.author | Alparslan, Volkan | |
dc.contributor.author | Tuna, Verda | |
dc.contributor.author | Yıldız, Mürşide | |
dc.contributor.author | Şenoğlu, Nimet | |
dc.contributor.author | Kıraklı, Cenk | |
dc.contributor.author | Yıldırım, Süleyman | |
dc.contributor.author | Saraç Kübüç, Kübra | |
dc.contributor.author | Erer, Ayşen | |
dc.contributor.author | Gültekin, Hamza | |
dc.contributor.author | Özmen Süner, Kezban | |
dc.contributor.author | Kuzgun, Özge | |
dc.contributor.author | Öztürk, Çağatay Erman | |
dc.contributor.author | Karahan, Aydın | |
dc.contributor.author | Deveci, Okan | |
dc.contributor.author | Ay, Mustafa | |
dc.contributor.author | Tüfek Öztan, Dilara | |
dc.contributor.author | Akıncı, Seda Banu | |
dc.contributor.author | Yalçın Solak, Melahat | |
dc.contributor.author | Bozbay, Süha | |
dc.contributor.author | Özçiftçi, Serhat | |
dc.contributor.author | Gönderen, Kamil | |
dc.contributor.author | Küçük, Ahmet Oğuzhan | |
dc.contributor.author | Uyan, Berna | |
dc.contributor.author | Elay, Gülseren | |
dc.contributor.author | Boyacı, Nazlıhan | |
dc.contributor.author | Timurkaan, Mustafa | |
dc.contributor.author | Karakoç, Ebru | |
dc.contributor.author | Doğan, Lerzan | |
dc.contributor.author | Yalçınkaya, Erdem | |
dc.contributor.author | Kazancıoğlu, Leyla | |
dc.contributor.author | Erdal Dönmez, Gül | |
dc.contributor.author | Yılmaz, Barış | |
dc.contributor.author | Ergül, Dursun Fırat | |
dc.contributor.author | Boran, Maruf | |
dc.contributor.author | Özkarakaş, Hüseyin | |
dc.contributor.author | Karakaş, Buğra | |
dc.contributor.author | Ergin Özcan, Perihan | |
dc.contributor.author | Anaklı, İlkay | |
dc.contributor.author | Bayar, Mustafa Kemal | |
dc.contributor.author | Yüksel, Didem | |
dc.contributor.author | Akdağ, Şükriye | |
dc.contributor.author | Pişkin, Özcan | |
dc.contributor.author | Temur, Sibel | |
dc.contributor.author | Eyüpoğlu, Selin | |
dc.contributor.author | Tekir Yılmaz, Elvan | |
dc.contributor.author | Zaim Avcı, Gizem | |
dc.contributor.author | Turan, Raziye | |
dc.contributor.author | Alkan Bayburt, Fatma | |
dc.contributor.author | Şahintürk, Helin | |
dc.contributor.author | Güçyetmez, Bülent | |
dc.contributor.author | Alparslan, Mustafa Muhlis | |
dc.contributor.author | Yarıcı, Metin | |
dc.contributor.author | Yıldırım, Fatma | |
dc.contributor.author | Yektaş, Abdulkadir | |
dc.contributor.author | Yaman, Güçlü | |
dc.contributor.author | Demirkıran, Oktay | |
dc.contributor.author | Cinel, İsmail | |
dc.date.accessioned | 2023-10-30T07:16:12Z | |
dc.date.available | 2023-10-30T07:16:12Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Gül, F., Kasapoğlu, U. S., Sabaz, M. S., Ay, P., Oktay, B. D., Çalışkan, G., Demir, N., Sayan, İ., Kabadayı, F., Altuntaş, G., Gümüş, A., Kırca, H., Şanlı, D., Acil, F., Dedeoğlu, A., Ural, S. G., Akın Şen, İ., Macit Aydın, E., Dayanır, H., Yelken, B., … Cinel, İ. (2023). The Impact of CoronaVac Vaccination on 28-day Mortality Rate of Critically Ill Patients with COVID-19 in Türkiye. Balkan medical journal, 40(6), 435–444. https://doi.org/10.4274/balkanmedj.galenos.2023.2023-6-90 | en_US |
dc.identifier.citation | 10.4274/balkanmedj.galenos.2023.2023-6-90 | en_US |
dc.identifier.issn | 2146-3131 | |
dc.identifier.issn | 2146-3123 | |
dc.identifier.uri | https://doi.org/10.4274/balkanmedj.galenos.2023.2023-6-90 | |
dc.identifier.uri | https://hdl.handle.net/11436/8598 | |
dc.description.abstract | Background: Vaccines against coronavirus disease-19 (COVID-19)
have been effective in preventing symptomatic diseases,
hospitalizations, and intensive care unit (ICU) admissions. However,
data regarding the effectiveness of COVID-19 vaccines in reducing
mortality among critically ill patients with COVID-19 remains unclear.
Aims: To determine the vaccination status and investigate the impact
of the COVID-19 vaccine on the 28-day mortality in critically ill
patients with COVID-19.
Study Design: Multicenter prospective observational clinical study.
Methods: This study was conducted in 60 hospitals with ICUs
managing critically ill patients with COVID-19. Patients aged ≥
18 years with confirmed COVID-19 who were admitted to the ICU
were included. The present study had two phases. The first phase
was designed as a one-day point prevalence study, and demographic
and clinical findings were evaluated. In the second phase, the 28-day
mortality was evaluated.
Results: As of August 11, 2021, 921 patients were enrolled in the
study. The mean age of the patients was 65.42 ± 16.74 years, and
48.6% (n = 448) were female. Among the critically ill patients with
COVID-19, 52.6% (n = 484) were unvaccinated, 7.7% (n = 71) were
incompletely vaccinated, and 39.8% (n = 366) were fully vaccinated.
A subgroup analysis of 817 patients who were unvaccinated (n =
484) or who had received two doses of the CoronaVac vaccine (n =
333) was performed. The 28-day mortality rate was 56.8% (n = 275)
and 57.4% (n = 191) in the unvaccinated and two-dose CoronaVac
groups, respectively. The 28-day mortality was associated with age,
hypertension, the number of comorbidities, type of respiratory support,
and APACHE II and sequential organ failure assessment scores (p <
0.05). The odds ratio for the 28-day mortality among those who had
received two doses of CoronaVac was 0.591 (95% confidence interval:
0.413-0.848) (p = 0.004).
Conclusion: Vaccination with at least two doses of CoronaVac within
six months significantly decreased mortality in vaccinated patients
than in unvaccinated patients. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Galenos Yayıncılık | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | The impact of CoronaVac vaccination on 28-day mortality rate of critically Ill patients with COVID-19 in Türkiye | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Kazancıoğlu, Leyla | |
dc.identifier.volume | 40 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 435 | en_US |
dc.identifier.endpage | 444 | en_US |
dc.relation.journal | Balkan Medical Journal | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |