Başlık için Scopus İndeksli Yayınlar Koleksiyonu listeleme
Toplam kayıt 5221, listelenen: 3957-3976
-
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
(Verduci Publisher, 2014)OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
The protective effect of melatonin and agomelatin against cisplatin-induced nephrotoxicity and oxidative stress in the rat kidney
(Colegio Farmaceuticos Provincia de Buenos Aires, 2013)Cisplatin is used to treat various types of cancers. Its use is limited, however, due to nephrotoxicity, which may result from free radical damage. Evidence exists that melatonin reduces oxidative stress-induced damage. ... -
Protective effect of mirtazapine against cisplatin-induced oxidative stress and DNA damage in guinea pig ear
(Scientific Publishers India, 2014)Cisplatin ototoxicity is a major dose-limiting factor in the treatment of several neoplastic diseases. Oxidative stress might play an important role of pathogenesis of cisplatin ototoxicity. the aim of this study was to ... -
Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: Effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels
(Polish Acad Sciences Inst Pharmacology, 2014)Background: Nimesulide is a pharmacological agent and selective COX-2 inhibitor. It has anti-inflammatory, analgesic and antipyretic properties. the purpose of this study was to investigate the effect of nimesulide on ... -
Protective effect of Panax ginseng against serum biochemical changes and apoptosis in kidney of rats treated with gentamicin sulphate
(Springer Link, 2012)The protective effects of Panax ginseng (PG) on gentamicin sulphate (GS) induced acute nephrotoxicity were investigated in rats. A total of 32 adult Sprague- Dawley rats were randomly divided into 4 equal groups and treated ... -
Protective effect of Panax ginseng against serum biochemical changes and apoptosis in liver of rats treated with carbon tetrachloride (CCl 4)
(Elsevier, 2011)The purpose of this study was to investigate possible beneficial effects of Panax ginseng (PG) on carbon tetrachloride (CCl 4)-induced acute hepatotoxicity in rats. CCl 4 challenge elevated serum enzyme activities of liver ... -
Protective effect of resveratrol against methotrexate-induced oxidative stress in the small intestinal tissues of rats
(E-Century Publishing Corp, 2015)The effect of resveratrol on the damage induced by methotrexate (MTX) in rat duodenum and jejunum tissue was investigated and evaluated in comparison with famotidine. the rats were divided into four groups as healthy group ... -
The protective effect of syringic acid on ischemia injury in rat brain
(2015)Background/aim: Brain ischemia and treatment are important topics in neurological science. Free oxygen radicals and inflammation formed after ischemia are accepted as the most significant causes of damage. Currently there ... -
Protective effect of tea grape extract on cisplatin-induced muscle atrophy: A morphological study
(Kowsar Publ, 2018)Background: Even though Cisplatin (Cis) is known to be organotoxic, it is used in neoplastic chemotherapy. in skeletal muscles, the toxic effect manifests as atrophy. Objectives: the tea grape extract (TGE) is a sort of ... -
The protective effect of thiamine pryophosphate against sugar-induced retinal neovascularisation in rats
(Verlag Hans Huber, 2018)The aim of this study was to investigate the effect of thiamine pyrophosphate (TPP), administered via sugar water, on retinal neovascularisation in rats. Animals were assigned to three groups, namely the TPP sugar-water ... -
Protective effect of thymoquinone in preventing trauma-related damage: an experimental study
(Taylo & Francis Ltd., 2021)Background Secondary injury is a potentially modifiable factor of outcome in traumatic brain injury. This study aimed to investigate thymoquinone's effects on trauma-induced neuronal damage. Methods Eighteen adult female ... -
Protective effect of whortleberry extract on salivary gland damage induced by neck irradiation in rats
(Sage Publications Inc, 2019)Radiotherapy is a method of treatment used on malignant head and neck tumors; however, it may lead to adverse effects by influencing other tissues because its effects are not specific to tumor tissues. These adverse effects ... -
The protective effects of adalimumab on intestinal injury induced with infrarenal aortic occlusion
(Turkish Assoc Trauma Emergency Surgery, 2020)BACKGROUND: the present study aims to observe the effects of ischemia-reperfusion (IR) on small intestines at a molecular level and to prospectively assess the potential preventive role of adalimumab (ADA) and antioxidants. ... -
Protective effects of amifostine, curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damage in rats
(Spandidos Publ Ltd, 2018)Cisplatin is an effective antineoplastic drug that is usually used to treat a number of different types of cancer in the clinic. One of the most notable side effects of cisplatin use is infertility. the present study was ... -
Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury
(Springer, 2018)Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ... -
The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation
(Pergamon-Elsevier Science Ltd, 2020)Aims: Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately 2.38 million people a year die from respiratory ... -
The protective effects of astaxanthin against cisplatin-induced retinal toxicity
(Taylor & Francis Ltd, 2019)Purpose: This study investigated the toxic effects of an antineoplastic agent, cisplatin (CIS), on retinal cells and the potential capacity of astaxanthin (ASTA) to elicit a future therapeutic protocol in CIS-induced retinal ... -
Protective effects of beta glucan in brain tissues of post-menopausal rats: a histochemical and ultra-structural study
(Taylor & Francis Ltd, 2016)Decline of estrogen during menopause has been associated with numerous significant changes that have been linked to many pathophysiological complications. in addition, ovarian hormone deficiency increases the production ...
