Yazar "RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" için TR-Dizin İndeksli Yayınlar Koleksiyonu listeleme
-
Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
Saral, Sinan; Kaya, Ali Koray; Topçu, Atilla; Öztürk, Aykut; Sümer, Ayşegül; Pınarbaş, Esra (Sakarya Üniversitesi, 2021)Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2) agonisti ve serotonin reseptör (5-HT2C) antagonisti olan antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ... -
Akut mezenterik iskemi tanılı hastanın operasyon sonrası nazogastrik sondasından çıkan Ascaris lumbricoides: Olgu sunumu
Ascaris lumbricoides insanlarda sık rastlanan barsak helmintidir. Bu, özellikle sıcak ve kırsal bölgelerde, sosyoekonomik düzeyi düşük toplumları etkileyen bir parazittir. Ascaris lumbricoides, parazitin hareketliliği ... -
Antimicrobial susceptibility and molecular characterization of multidrug-resistant acinetobacter baumannii isolated in an university hospital
Direkel, Şahin; Çiçek, Ayşegül Çopur; Karagöz, Alper; Aydoğan Ejder, Nebahat; Oktay, Efdal; Delialioğlu, Nuran; Özgümüş, Osman Birol; Durmaz, Rıza (Ankara Microbiology Soc, 2016)Acinetobacter baumannii, an aerobic, non-motile, gram-negative bacterium is an important nosocomial pathogen which shows resistance to the most antibiotics. Carbapenems are the most commonly used antibiotics for the treatment ... -
Assessment of association rule mining using ınterest measures on the gene data
Akbaş, Kübra Elif; Kıvrak, Mehmet; Arslan, Ahmet Kadir; Yakınbaş, Tuğçe; Korkmaz, Hasan; Önalan, Ebru (Medical records-international medical journal, 2022)Aim: Data mining is the discovery process of beneficial information, not revealed from large-scale data beforehand. One of the fields in which data mining is widely used is health. With data mining, the diagnosis and ... -
Association and haplotype analysis of the PON1, ITGB3 and CYP3A4 genes, strong candidates for familial coronary artery disease susceptibility
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özbayer, Cansu; Ulus, Taner; Özdemir, Mahmut; Ata, Necmi; Güneş, Hasan Veysi (2023)Objective: Genetic predisposition is very common among the patients with coronary artery disease (CAD), a complex and multifactorial disease. Our objective was to determine the possible association between the most ... -
Autoantibodies against carbonic anhydrase I and II in patients with acute myeloid leukemia
Menteşe, Ahmet; Erkut, Nergiz; Demir, Selim; Yaman, Serap Özer; Sümer, Ayşegül; Doğramacı, Şeniz; Alver, Ahmet; Sönmez, Mehmet (2017)Amaç: Kanser, dünyadaki başlıca ölüm nedenlerinden birisi olup, küresel bir toplum sağlığı sorunudur. Organizmanın kendi antijenlerine karşı gelişen otoantikorlar pek çok kanser hastasının serumunda tespit edilmiştir. Son ... -
Avokado/soya fasülyesinin sabunlaşmayan ekstresi verilen köpeklerin dizlerinde osteokondral defekt iyileşmesi: Bir karşılaştırmalı morfometrik analiz
Altınel, Levent; Şahin, Önder; Köse, Kamil Çağrı; Baş, Orhan; Özen, Oğuz Aslan; Sarıtaş, Z. Kadir; Pamuk, Kamuran (2011)Amaç: Bu çalışmada avocado/soya fasülyesinin sabunlaşmayan ekstresinin (ASE) köpek osteokondral defekt modelinde iyileşmeye etkisi belirlendi. Gereç ve yöntemler: On dört köpek çalışmaya alındı ve rastgele olarak iki gruba ... -
Biochemical and histopathological investigation of liver tissues on high fat diet fed rats
Samancı, Tuğba Çelik; Gökçimen, Alpaslan; Kuloğlu, Tuncay; Boyacıoğlu, Murat; Kuyucu, Yurdun; Polat, Sait (Galenos Yayıncılık, 2022)Objective: Hepatic steatosis is a common cause of liver disease and has become more prevalent recently. This study was conducted to investigate the biochemical and histopathological changes in the liver tissue high fat ... -
Chromosomal findings and sequence analysis of target exons of calcium-sensing receptor (CaSR) gene in patients with Sagliker syndrome
Tunç, Erdal; Demirhan, Osman; Sağlıker, Yahya; Yıldız, İsmail; Paylar, Nuray; Güzel, Ali İrfan (2017)Background/aim: Sagliker syndrome (SS) develops as a continuation of chronic kidney disease and secondary hyperparathyroidism conditions. It was thought that there are some genetic predisposition factors leading to SS. The ... -
Chronic restraint stress impairs spatial memory while decreasing hippocampal BDNF levels in rats
Saral, Sinan; Sümer, Ayşegül; Kaya, Ali Koray; Öztürk, Aykut; Topçu, Atilla (İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: This study investigated the potential role of chronic restraint stress (CRS) on spatial memory, recognition memory, brain-derived neurotrophic factor (BDNF) and acetylcholine (ACh) levels in young adult rats. Material ... -
Comparison of DNA isolation methods from mammalian sperm cells and development of a new protocol
Nalkıran, Hatice Sevim; Nalkıran, İhsan; Rakıcı, Sema Yılmaz; Tümkaya, Levent; Güzel, Ali İrfan (Effect Publishing Agency ( EPA ), 2021)Sperm DNA tightly packed with protamines makes the DNA isolation procedure from sperm cells long and laborious. Cell lysis is also a challenging step because of the disulfide bonds-rich membranes of the sperm cells. In ... -
Comparison of respiratory tract pathogens and antibiotic susceptibility profiles of patients diagnosed with COVID-19 with pre-COVID-19
Şenol, Feray Ferda; Bahçeci, İlkay; Arslan, Nuray; Aytaç, Özlem; Öner, Pınar; Aşçı Toraman, Zülal (MediHealth Academy Yayıncılık, 2022)Objective: It is aimed to compare the respiratory tract agents and antibiotic resistance rates in patients with a diagnosis of COVID-19 with the non-COVID-19 period. Material and Method: Patients diagnosed with bacterial ... -
Covid-19 hastalarında kardiyak troponin-ı’nın cinsiyet ilişkili prognostik değeri
Kant, Aydın; Aydın, Ercan; Kılıç Yılmaz, Hülya; Yılmaz, Gürdal (Kırıkkale Üniversitesi, 2021)Amaç: Kardiyak troponinler kardiyak ve non-kardiak birçok hastalıkta yükselebilmektedir. Çalışmamızda COVID-19 hastalarının hastaneye kabulünde kardiyak troponin-I seviyesinin yoğun bakım ihtiyacı ve tüm nedenlere ... -
Çeşitli klinik örneklerden izole edilen gram negatif gsbl pozitif bakterilerin antibiyotiklere direnç oranları
Şenol, Feray Ferda; Bahçeci, İlkay; Aytaç, Özlem; Öner, Pınar; Aşçı Toraman, Zülal (DNT Ortadoğu Yayıncılık A.Ş., 2021)Amaç: Genişlemiş Spektrumlu Beta Laktamaz (GSBL) pozitif mikroorganizmaların neden olduğu enfeksiyonların tedavisindeki zorluklar günümüzde en önemli sağlık sorunlarından biridir. çeşitli bakteriyolojik kültürlerinden ... -
Çeşitli klinik örneklerden izole edilen stenotrophomonasmaltophilia suşlarının dağılımı ve antimikrobiyal duyarlılıkları: 8 yıllık çalışma
Bahçeci, İlkay; Kostakoğlu, Uğur; Duran, Ömer Faruk; Yıldız, İlknur Esen; Dilek, Aziz Ramazan (2021)Amaç: Hastane enfeksiyonları ve buna bağlı mortalitenin artması çoklu ilaç direncine sahip fırsatçı patojenleri her zamankinden daha fazla gündeme getirmiştir. Bunlar arasında yer alan stenotrophomonas maltophilia önemi ... -
Early diagnosis of diabetes mellitus by machine learning methods according to plasma glucose concentration, serum ınsulin resistance and diastolic blood pressure ındicators
Kıvrak, Mehmet (Effect Publishing Agency ( EPA ), 2022)Aim: It is a known fact that diabetes mellitus is increasing frequently and triggering many different diseases. Therefore, early diagnosis of the disease is important. This study was trying to predict the early diagnosis ... -
Effect of 900-MHz electromagnetic field on the cerebellum: a histopathological investigation
Objectives: The currently widely used technological devices give rise to electromagnetic fields (EMFs) at various frequencies. Recent studies have reported that EMFs damage the central nervous system. The cerebellum is of ... -
The effect of usnea longissima extract on lung cancer cell line (A549)
Objective: Some lichens are known to demonstrate anticancer activity. However, to the best of our knowledge, no information is available about the activity of Usnea longissima against human lung cancer A549 cells. This ... -
The effects of prenatal long-duration exposure to 900-MHz electromagnetic field on the 21-day-old newborn male rat liver
Suzan, Zehra Topal; Hancı, Hatice; Mercantepe, Tolga; Erol, Hüseyin Serkan; Keleş, Osman Nuri; Kaya, Haydar; Mungan, Sevdegül; Odacı, Ersan (Tübıtak Scıentıfıc & Technıcal Research Councıl Turkey, 2015)Background/aim: To determine what efect a 900-MHz electromagnetic feld (EMF) applied in the prenatal period would have on the liver in the postnatal period. Materials and methods: At the start of the study, adult pregnant ... -
The effects of royal jelly on the oxidantantioxidant system in rats with N-methyl- N-nitrosourea-induced breast cancer
Malkoç, Meltem; Altay, Diler Us; Alver, Ahmet; Ersöz, Şafak; Şen, Tuğba Mazlum; Kural, Birgül Vanizor; Uydu, Hüseyin Avni (2018)Objectives: To determine the effect of royal jelly (RJ) on the oxidant-antioxidant balance in rats with N-methyl-Nnitrosourea (MNU) induced breast cancer and to compare this with the chemotherapeutic agent paclitaxel. ...