Kurum Yazarı "Emirik, Mustafa" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
-
Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
Güven, Okan; Menteşe, Emre; Emirik, Mustafa; Sökmen, Bahar Bilgin; Akyüz, Gülay (Wiley, 2023)This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ... -
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
Menteşe, Emre; Emirik, Mustafa; Sökmen, Bahar Bilgin (Academic Press Inc Elsevier Science, 2019)A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ... -
Molecular docking studies and synthesis of novel bisbenzimidazole derivatives as inhibitors of alpha-glucosidase
Özil, Musa; Emirik, Mustafa; Beldüz, Ali; Ülker, Serdar (Pergamon-Elsevier Science Ltd, 2016)A series of bisbenzimidazole derivatives starting from o-phenylenediamine and 4-nitro-o-phenylenediamine were prepared with oxalic acid. Most of the reactions were conducted using both the microwave and conventional methods ... -
A novel ferrocenyl naphthoquinone fused crown ether as a multisensor for water determination in acetonitrile and selective cation binding
Dağdevren, Metin; Yılmaz, İsmail; Yücel, Barış; Emirik, Mustafa (Amer Chemical Soc, 2015)A multisensor which is based on a novel multifunctional triad molecule, ferrocenyl naphthoquinone fused crown ether (Fc-cnq) bearing ferrocene, quinone, and crown ether functional groups together, was synthesized and ... -
Potential therapeutic effect of turmeric contents against SARS-CoV-2 compared with experimental COVID-19 therapies: in silico study
Emirik, Mustafa (Taylor & Francis Inc, 2020)Inspired by the 'There is no scientific evidence that turmeric prevents COVID-19' statement made by WHO, the protective or therapeutic potential of the compounds in turmeric contents was investigated against COVID-19 with ... -
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
Özil, Musa; Emirik, Mustafa; Etlik, Semiha Yılmaz; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2016)A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ... -
Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies
Menteşe, Emre; Güner, Adem; Polatlı, Elifsu; Emirik, Mustafa; Bektaş, Hakan; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2020)The synthesis, docking study, and investigation of the anticancer activities of some coumarin derivatives containing the triazole ring are reported in this study. the newly synthesized compounds were screened for their in ... -
Synthesis and molecular docking study of some novel 2,3-disubstituted quinazolin-4(3H)-one derivatives as potent inhibitors of urease
Akyüz, Gülay; Menteşe, Emre; Emirik, Mustafa; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2018)A new series of 2,3-disubstituted quinazolin-4(3H)-one compounds including oxadiazole and furan rings was synthesized. Their inhibitory activities on urease were assessed in vitro. All newly synthesized compounds exhibited ... -
Synthesis of some novel quinazolin-4(3H)-one hybrid molecules as potent urease inhibitors
Menteşe, Emre; Akyüz, Gülay; Yılmaz, Fatih; Baltaş, Nimet; Emirik, Mustafa (Wiley-V C H Verlag Gmbh, 2018)A new series of quinazolinone hybrid molecules containing coumarin, furan, 1,2,4-triazole and 1,2,4-thiadiazole rings was designed, synthesized, and screened for their urease inhibition activities. All newly synthesized ... -
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
Menteşe, Emre; Baltaş, Nimet; Emirik, Mustafa (Academic Press Inc Elsevier Science, 2020)In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ... -
Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities
Menteşe, Emre; Akyüz, Gülay; Emirik, Mustafa; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2019)A new series of quinazolinone derivatives containing triazole, thiadiazole, thiosemicarbazide functionalities was synthesized and then screened for their in vitro urease inhibition properties. Most of the compounds showed ... -
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
Menteşe, Emre; Yılmaz, Fatih; Emirik, Mustafa; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2018)In this study, a new series of benzimidazole and bisbenzimidazole derivatives were prepared via the reaction of iminoester hydrochlorides and o-phenylenediamines and then screened for their lipase inhibition properties. ... -
Ternary transition metal complexes with an azo-imine Lligand and 2,2'-bipyridine: Characterization, computational calculations, and acetylcholinesterase inhibition activities
Serbest, Kerim; Dural, Turan; Kızıl, Demet; Emirik, Mustafa; Zengin, Ali; Dinçer, Barbaros (Slovensko Kemijsko Drustvo, 2022)New mononuclear ternary transition metal complexes: [M(HL)(bipy)2]ClO4, (M: Mn(II) for 1, Ni(II) for 2), [M(HL) (bipy) (ClO4)], (M: Ni(II) for 3, Cu(II) for 4, Zn(II) for 5) with M(II), 2-[(hydroxyimino)methyl]-4-[-phenyldiazenyl] ...