Kurum Yazarı "Menteşe, Emre" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
Güven, Okan; Menteşe, Emre; Emirik, Mustafa; Sökmen, Bahar Bilgin; Akyüz, Gülay (Wiley, 2023)This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ... -
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
Menteşe, Emre; Emirik, Mustafa; Sökmen, Bahar Bilgin (Academic Press Inc Elsevier Science, 2019)A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ... -
Design, synthesis, and biological evaluation of coumarin-triazole hybrid molecules as potential antitumor and pancreatic lipase agents
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Ülker, Serdar (Wiley-V C H Verlag Gmbh, 2017)The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation ... -
Microwave assisted synthesis and anti-lipase activity of some new fluorine-containing benzimidazoles
Menteşe, Emre; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Georg Thieme Verlag Kg, 2015)In this study, a new series of fluorine containing benzimidazoles (4a-l) and bisbenzimidazoles (6a-c, 8) were synthesized by the reaction of o-phenylenediamines with iminoester hydrochlorides (3a-l, 7) in methanol under ... -
Microwave-assisted synthesis and biological evaluation of some benzimidazole derivatives containing a 1,2,4-triazol ring
Menteşe, Emre; Karaali, Nesrin; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2013)A new series of 2-(4-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole derivatives containing a 1,2,4-triazole ring were synthesized via microwave technique. This efficient procedure provides pure products within a few minutes. ... -
A new fluorescent "turn-off" coumarin-based chemosensor: Synthesis, structure and Cu-selective fluorescent sensing in water samples
Karaoğlu, Kaan; Yılmaz, Fatih; Menteşe, Emre (Springer/Plenum Publishers, 2017)We report the synthesis and characterization two coumarin-based fluorescence probes, N'-{[7-(diethylamino)-2-oxo-2H-chromen-3-yl]carbonyl}pyridine-3-carbohydrazide (3) and N'-benzoyl-7-(diethylamino)-2-oxo-2H-chromene-3- ... -
Novel coumarin derivatives containing a triazole moiety: A study on synthesis, cytotoxicity, membrane dysfunction, apoptosis, cell cycle, and antiangiogenic effects
Güner, Adem; Bektaş, Hakan; Menteşe, Emre (Bentham Science Publications, 2022)Background: Coumarin is a functional compound with a pronounced wide range of biological activities and has recently been shown to have anticancer effects on various human cancer cells. Cisplatin is widely used in treating ... -
Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies
Menteşe, Emre; Güner, Adem; Polatlı, Elifsu; Emirik, Mustafa; Bektaş, Hakan; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2020)The synthesis, docking study, and investigation of the anticancer activities of some coumarin derivatives containing the triazole ring are reported in this study. the newly synthesized compounds were screened for their in ... -
Synthesis and antioxidant activities of some new triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings
Menteşe, Emre; Yılmaz, Fatih; Baltaş, Nimet; Bekircan, Olcay; Kahveci, Bahittin (Taylor & Francis Ltd, 2015)Various triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings (3-6) were synthesized and screened for their antioxidant activities. the structures of the synthesized compounds (2-6) were ... -
Synthesis and kinetics studies of N '-(2-(3,5-disubstituted-4H-1,2,4-triazol-4-yl)acetyl)-6/7/8-substituted-2-oxo-2H-chromen-3-carbohydrazide derivatives as potent antidiabetic agents
Menteşe, Emre; Baltaş, Nimet; Bekircan, Olcay (Wiley-V C H Verlag Gmbh, 2019)A novel series of N '-(2-(3,5-disubstituted-4H-1,2,4-triazol-4-yl)acetyl)-6/7/8-substituted-2-oxo-2H-chromen-3-carbohydrazides were synthesized and studied for their alpha-glucosidase inhibition activity. Most of the ... -
Synthesis and molecular docking study of some 5,6-dichloro-2cyclopropyl-1H-benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease
Menteşe, Emre; Bektaş, Hakan; Sökmen, Bahar Bilgin; Emirik, Mustafa; Çakır, Demet; Kahveci, Bahittin (Pergamon-Elsevier Science Ltd, 2017)A new series of benzimidazole compounds including hydrazinecarbothioamide, 1,2,4-triazole, 1,3,4-oxadiazole and imine function were synthesized starting from 5,6-dichloro-2-cyclopropyl-1H-benzimidazole. All of the benzimidazole ... -
Synthesis and molecular docking study of some novel 2,3-disubstituted quinazolin-4(3H)-one derivatives as potent inhibitors of urease
Akyüz, Gülay; Menteşe, Emre; Emirik, Mustafa; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2018)A new series of 2,3-disubstituted quinazolin-4(3H)-one compounds including oxadiazole and furan rings was synthesized. Their inhibitory activities on urease were assessed in vitro. All newly synthesized compounds exhibited ... -
Synthesis and spectroscopic characterization of novel methoxy bridged benzimidazolyl-substituted phthalocyanines as potent inhibitors of urease
Akçay, Hakkı Türker; Menteşe, Emre; Sökmen, Bahar Bilgin (Pergamon-Elsevier Science Ltd, 2020)In this study, novel peripherally 4-[(1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4) and Co(II) (5) phthalocyanines were prepared and their structures were characterized spectroscopically. the light ... -
Synthesis of some new 1,2,4-triazole derivatives starting from 3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol with anti-lipase and anti-urease activities
Bekircan, Olcay; Menteşe, Emre; Ülker, Serdar; Küçük, Çağatay (Wiley-V C H Verlag Gmbh, 2014)In the present study, starting compound 4 was prepared by deamination of compound 2 in the presence of hypophosphorous acid and sodium nitrite. Treatment of compound 4 with ethyl bromoacetate produced ethyl[3-(4-chloroph ... -
Synthesis of some novel 1,2,4-triazol-3-one derivatives bearing the salicyl moiety and their anticonvulsant activities
Kahveci, Bahittin; Menteşe, Emre; Akkaya, Emre; Yılmaz, Fatih; Doğan, İnci Selin; Özel, Arzu (Wiley-V C H Verlag Gmbh, 2014)A series of new 1,2,4-triazole-3-one derivatives bearing the salicyl moiety were synthesized by using microwave irradiation, and their chemical structures were identified by IR, H-1 NMR, C-13 NMR, elemental analysis, and ... -
Synthesis of some novel heterocylic compounds derived from 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl]acetohydrazide and investigation of their lipase and alpha-glucosidase inhibition
Bekircan, Olcay; Ülker, Serdar; Menteşe, Emre (Taylor & Francis Ltd, 2015)In the present study, 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl]acetohydrazide (1) was used as starting compound for the synthesis of 2-{[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl ... -
Synthesis of some novel quinazolin-4(3H)-one hybrid molecules as potent urease inhibitors
Menteşe, Emre; Akyüz, Gülay; Yılmaz, Fatih; Baltaş, Nimet; Emirik, Mustafa (Wiley-V C H Verlag Gmbh, 2018)A new series of quinazolinone hybrid molecules containing coumarin, furan, 1,2,4-triazole and 1,2,4-thiadiazole rings was designed, synthesized, and screened for their urease inhibition activities. All newly synthesized ... -
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
Menteşe, Emre; Baltaş, Nimet; Emirik, Mustafa (Academic Press Inc Elsevier Science, 2020)In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ... -
Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities
Menteşe, Emre; Akyüz, Gülay; Emirik, Mustafa; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2019)A new series of quinazolinone derivatives containing triazole, thiadiazole, thiosemicarbazide functionalities was synthesized and then screened for their in vitro urease inhibition properties. Most of the compounds showed ... -
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
Menteşe, Emre; Yılmaz, Fatih; Emirik, Mustafa; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2018)In this study, a new series of benzimidazole and bisbenzimidazole derivatives were prepared via the reaction of iminoester hydrochlorides and o-phenylenediamines and then screened for their lipase inhibition properties. ...