Chemical and biological activities of callistemon citrinus and punica granatum

Abstract

Abstract: Plants have great potential for researchers with their active ingredients. In the study, extracts of Callistemon citrinus (Brush bush) and Punica granatum (Pomegranate) bark plants were prepared at 2.5 and 5 concentrations. The antimicrobial activities of the extracts were investigated by the agar well method against various Gram negative, Gram positive bacteria and two Candida species. Anti Quorum sensing activity was investigated with Chromobacterium violaceum and Pseudomonas aeruginosa strains. In addition, its antioxidant properties were screened by the DPPH (1,1-Diphenyl-2-picrylhydrazil radical; C18H12N5O6) method. According to the findings obtained as a result of the study, it was seen that both plants were effective in terms of antimicrobial activity. Antioxidant property scans show that 2.5% concentration data is more successful than the data of 5% concentration extracts. As a result of the study, it was observed that the plants were rich in new antibiotic active substances and bioactive substances. Antibiotic resistance, which has increased rapidly in recent years, is one of the leading public health threats. Researchers are searching for alternative methods for new and effective antibiotics to combat resistance. Different methodologies such as quarum sensing have gained importance in the search for active substances. It was determined that antiquarum detection activity was especially high in pomegranate extract groups.