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The role of AMY1 gene copy number variation in dental caries susceptibility: insights from a Turkish population
(Springer Nature, 2025)Objective: Dental caries is a multifactorial disease influenced by environmental, behavioral, and genetic factors. Recent studies suggest that variations in the AMY1 gene, which encodes salivary amylase, may contribute to ... -
Does fracture type or surgical technique influence mortality in elderly hip fracture patients?
(SAGE Publications Inc., 2025)Objective: To evaluate and compare the 1-year mortality outcomes of elderly patients with hip fractures treated with either hemiarthroplasty (HA) or proximal femoral nailing (PFN), focusing on both intracapsular and ... -
Effect of cumulative tobacco exposure on blood eosinophil level in chronic obstructive pulmonary disease
(John Wiley and Sons Ltd., 2025)Chronic obstructive pulmonary disease (COPD) is a lung condition characterized by persistent airway obstruction and is associated with various phenotypes and endotypes. While eosinophilic inflammation is typically seen in ... -
Investigation of the relationship between endometrial cancer and liver fibrosis-4 score
(Wolters Kluwer Medknow Publications, 2025)Objectives: We investigated the relationship between the degree of fibrosis and endometrial cancer (EC) by calculating the fibrosis-4 (FIB-4) score, a noninvasive marker for measuring the severity of liver fibrosis. Materials ... -
Alternative splicing: hallmark and therapeutic opportunity in metabolic liver disease
(Oxford University Press, 2025)Metabolic dysfunction-associated fatty liver disease (MAFLD) has become the leading cause of chronic liver disease worldwide, with fibrosis recognized as the main prognostic factor and therapeutic target. While early-stage ... -
Complement dysregulation at lymphatics
(Elsevier, 2025)The complement system is a central component of innate immunity, orchestrating pathogen clearance while regulating inflammation, tissue repair, and homeostasis. Its activation is tightly controlled by multiple inhibitors ... -
Prognostic value of Aurora B expression in cancer patients: A meta-analysis
(SAGE Publications, 2025)Background: Overexpression of Aurora B is linked to poor prognosis in various malignancies; however, its prognostic role remains debatable. Conducting a meta-analysis is essential to reach a definitive conclusion. Methods: ... -
Pathophysiology and evaluation of bone health in adrenal diseases
(Springer, 2025)Adrenal diseases are associated with an increased risk of osteopenia/osteoporosis and fragility fractures. Although dual-energy X-ray absorptiometry remains the gold standard for assessing bone mineral density, its limitations ... -
UPPS-P impulsive behavior scale for children: turkish adaptation, reliability and validity study
(Turkish Association of Nervous and Mental Health, 2025)Objective: In this study we aimed to examine the Turkish validity and reliability of the UPPS-P Impulsive Behavior Scale for Children (UPPS-P-C) and to investigate whether there is a relationship between the UPPS-P-C ... -
Epithelial barrier hypothesis in the context of nutrition, microbial dysbiosis, and immune dysregulation in metabolic dysfunction-associated steatotic liver
(Frontiers Media SA, 2025)In recent years, the prevalence of chronic liver diseases, particularly Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), has increased significantly. This upward trend is largely associated with lifestyle-related ... -
Is visceral fat thickness related to outcomes in cancer patients with pulmonary embolism?
(Associacao Medica Brasileira, 2025)OBJECTIVE: The aim of this study was to determine the relationship between visceral fat thickness measurements obtained via computed tomography and clinical outcomes in order to predict the outcomes of oncology patients ... -
Comparison of optic nerve sheath diameter measurements in coronary artery bypass grafting surgery with pulsatile and non-pulsatile flow
(MDPI, 2025)Background and Objectives: In coronary artery bypass grafting (CABG) surgeries, monitoring intracranial pressure (ICP) is crucial due to neurological risks. Although pulsatile flow (PF) during cardiopulmonary bypass (CPB) ... -
In silico identification of LSD1 inhibition-responsive targets in small cell lung cancer
(MDPI, 2025)Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy characterized by rapid progression, high metastatic potential, and limited therapeutic options. Lysine-specific demethylase 1 (LSD1) has been identified ... -
Exploring the prevalence and risk factors of MASLD in patients with newly diagnosed diabetes mellitus: a comprehensive investigation
(MDPI, 2025)Background: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) represents a growing concern in the context of metabolic disorders, particularly among individuals diagnosed with type 2 diabetes mellitus (T2DM). ... -
Bis(azo-mine) based transition metal complexes: synthesis, spectroscopy, DNA binding, docking studies, and α-glucosidase inhibition activity
(John Wiley and Sons Ltd, 2025)In this work, two new mononuclear transition metal complexes: [M(L)], (M: Zn(II) for 2a, Mn(II) for 2b), with H2L (2,2′-{propane-1,3-diylbis[nitrilo(E)methylylidene]}bis{4-[(E)-phenyldiazenyl]phenol}, as the primary ligand ... -
The effects of surgical androgen deprivation therapy for advanced prostate cancer on peripapillary retinal nerve fiber layer thickness
(AVES, 2025)Background: Prostate cancer is the most common malignancy in men, and androgen deprivation therapy (ADT) serves as the primary approach for managing advanced cases. Certain research has suggested the impact of androgens ... -
Occurrence of antimicrobial resistance, integrons and virulence genes in Escherichia coli isolated from drinking water in Van, Turkiye: a cross-sectional study
(BioMed Central Ltd, 2025)Background: Escherichia coli is one of the recommended freshwater indicator organisms for faecal contamination and can be associated with the pool of genes encoding antibiotic resistance. The aim of this study was to ... -
What does radiologic assessment contribute to asthma: a subanalysis of the turkish adult asthma registry
(Springer International Publishing, 2025)Objectives: It is aimed to assess how physicians use chest imaging in asthma and the relationship between the pathological findings and related disease characteristics in the radiological imaging of asthmatic patients. ... -
The relationship between emotional expression, difficulty in emotion regulation and anhedonia in parkinson’s disease
(Routledge, 2025)Parkinson’s disease (PD), a range of neuropsychiatric symptoms, including anhedonia, depression, emotional control, and cognitive deficits, may manifest. This study aims to investigate the impact of anhedonia, emotional ... -
The use of stereological and electron microscopic techniques in the assessment of peripheral nerve regeneration success
(Elsevier, 2025)Morphological alterations in nerve tissue are commonly used as a hallmark in evaluating regeneration success in peripheral nerve studies. The use of stereological methods in the assessment of peripheral nerve and ganglion ...