Kurum Yazarı "Menteşe, Emre" FEF, Biyoloji Bölümü Koleksiyonu İçin Listeleme
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Design, synthesis, and biological evaluation of coumarin-triazole hybrid molecules as potential antitumor and pancreatic lipase agents
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Ülker, Serdar (Wiley-V C H Verlag Gmbh, 2017)The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation ... -
Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
Menteşe, Emre; Yılmaz, Fatih; Menteşe, Meltem; Beriş, Fatih Şaban; Emirik, Mustafa (Wiley, 2024)In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ... -
Ecofriendly solventless synthesis and reduction reaction of some triazole compounds and evaluation of their antimicrobial activity
Özil, Musa; Menteşe, Emre; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Taylor & Francis Inc, 2013)A number of triazole-3-one compounds have been synthesized, and reduction of the carbonyl group in the molecule has been carried out to give a corresponding hydroxyl group that possesses asymmetric carbon atom in good ... -
Effect of microwave irradiation on the synthesis of 1,2,4-triazol-3-one derivatives and their antimicrobial activities
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Beriş, Fatih Şaban (Science Reviews 2000 Ltd, 2012)An easy efficient method for the synthesis of N-(3,5-dichlorophenyl)-5-alkyl/aryl-3H-1,2,4-triazol-3-one derivatives under microwave irradiation has been developed using the reaction of 3,5-dichloroaniline and ethoxycarb ... -
An efficient synthesis of benzimidazoles via a microwave technique and evaluation of their biological activities
Kahveci, Bahittin; Menteşe, Emre; Özil, Musa; Ülker, Serdar; Ertürk, Murat (Springer Wien, 2013)A simple and practical protocol was developed for the synthesis of benzimidazoles. the protocol uses iminoester hydrochloride which is very useful in the reaction with 4,5-dichloro-1,2-phenylenediamine under microwave ... -
Microwave assisted synthesis and anti-lipase activity of some new fluorine-containing benzimidazoles
Menteşe, Emre; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Georg Thieme Verlag Kg, 2015)In this study, a new series of fluorine containing benzimidazoles (4a-l) and bisbenzimidazoles (6a-c, 8) were synthesized by the reaction of o-phenylenediamines with iminoester hydrochlorides (3a-l, 7) in methanol under ... -
Microwave assisted synthesis of some novel 2-(3-Chlorobenzyl)-1H-benzimidazole derivatives and determination of their antimicrobial activity and pKa values
Menteşe, Emre; Bekircan, Olcay; İslamoğlu, Fatih; Beriş, Fatih Şaban (Chiminform Data S A, 2015)In the present research, synthesis of new 2-(3-chlorobenzyl)-1H-benzimidazole derivatives bearing N-benzylidene, 1,2,4-triazole and N-acylhydrazone moiety is investigated. These novel compounds have been tested for their ... -
Microwave-assisted synthesis and biological evaluation of some benzimidazole derivatives containing a 1,2,4-triazol ring
Menteşe, Emre; Karaali, Nesrin; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2013)A new series of 2-(4-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole derivatives containing a 1,2,4-triazole ring were synthesized via microwave technique. This efficient procedure provides pure products within a few minutes. ... -
Microwave-assisted synthesis of some new benzimidazole derivatives with their antimicrobial activity
Menteşe, Emre; Yılmaz, Fatih; Beriş, Fatih Şaban; Bekircan, Olcay; Kahveci, Bahittin (Bentham Science Publ Ltd, 2015)2-(2-Chlorobenzyl)-1H-benzimidazole (2) was prepared from the reaction of o-phenylenediamine and ethylimido-o-chlorophenylacetate hydrochloride (1) under microwave irradiation. the acetate and hydrazide derivatives of 2(2- ... -
Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Ülker, Serdar (Springer, 2015)By using the microwave technology, a new protocol has been developed for the synthesis of new coumarin derivatives including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly ... -
Microwave-assisted synthesis of some novel benzimidazole derivatives containing imine function and evaluation of their antimicrobial activity
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay (Wiley, 2014)4-Bromo-o-phenylenediamine and ethylimido-p-bromophenylacetate, 1, were subjected to microwave irradiation to synthesize benzimidazole derivative, compound 2. Ester derivative, 3, and hydrazide derivative, 4, of compound ... -
Rapid and efficient microwave-assisted synthesis of some new triazol-3-one derivatives
Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Wiley, 2013)A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new triazol-3-ones via microwave ... -
Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives
Menteşe, Emre; Yılmaz, Fatih; Karaali, Nesrin; Ülker, Serdar; Kahveci, Bahittin (Maik Nauka/Interperiodica/Springer, 2014)This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. the structure of ... -
Study of antıoxidant, antimicrobial and anti-xanthine oxidase activities of some 5,6-dimethyl-2-(substituted)-1h-benzimidazoles and their acylhydrazide derivatives
Baltaş, Nimet; Beriş, Fatih Şaban; Menteşe, Emre (Raman Publ, 2017)In this study, a series of 5,6-dimethy1-2-(4-fluoro/chloro/bromo/methyl/nitrobenzy1)-1Hbenzimidazoles were screened for their bovine milk xanthine oxidase (XO) inhibition, antioxidant and antimicrobial activities. Compounds ... -
Synthesis and antimicrobial activity of some new triazole bridged benzimidazole substituted phthalonitrile and phthalocyanines
Kantar, Günay Kaya; Menteşe, Emre; Beriş, Fatih Şaban; Şaşmaz, Selami; Kahveci, Bahittin (Editura Acad Romane, 2018)In this study, some new phthalonitriles and metallophthalocyanines (Zn, Ni, Co, and Cu) containing triazole bridged benzimidazole moieties were synthesized starting from 2-(3-methylbenzyl)-1H-benzimidazole Newly synthesized ... -
Synthesis and evaluation of alpha-glucosidase and pancreatic lipase inhibition by quinazolinone-coumarin hybrids
Menteşe, Emre; Karaali, Nesrin; Akyüz, Gülay; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Springer, 2016)A new series of 2-substituted quinazolin-4(3H)-one derivatives including coumarin nucleus has been synthesized and screened for their lipase and a-glucosidase inhibition properties. Among the synthesized compounds, ... -
Synthesis and pharmacological activities of some new 2-[1-Heptyl-3-(4-methoxybenzyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl] acetohydrazide derivatives
Bekircan, Olcay; Menteşe, Emre; Ülker, Serdar (Walter de Gruyter Gmbh, 2014)In the present investigation, the key intermediate acetohydrazide derivative 5 was synthesized starting from 3-(4-methoxybenzyl)-4-amino-4,5-dihydro-1,2,4-triazol-5-one (1) by a four-step reaction. Thiosemicarbazides 6a-f ... -
Synthesis and study of alpha-glucosidase inhibitory, antimicrobial and antioxidant activities of some benzimidazole derivatives containing triazole, thiadiazole, oxadiazole, and morpholine rings
Menteşe, Emre; Ülker, Serdar; Kahveci, Bahittin (Springer, 2015)A new series of 2-(4-bromobenzyl)- and 2-(4-fluorobenzyl)-1H-benzimidazole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and morpholine rings has been synthesized. the structures of the newly ... -
Synthesis of novel 2,3-disubstituted quinazolin-4(3H)-one derivatives containing hydrazone skeleton as potent urease inhibitors and their antimicrobial activities
Akyüz, Gülay; Beriş, Fatih Şaban; Kahveci, Bahittin; Menteşe, Emre (Wiley, 2019)A new series of quinazolinones containing hydrazone moiety were synthesized, and their inhibitory activities on urease were assessed in vitro. Most of the compounds exhibited potent urease inhibitory activity. Among the ... -
Synthesis of some new 1,2,4-triazole derivatives starting from 3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol with anti-lipase and anti-urease activities
Bekircan, Olcay; Menteşe, Emre; Ülker, Serdar; Küçük, Çağatay (Wiley-V C H Verlag Gmbh, 2014)In the present study, starting compound 4 was prepared by deamination of compound 2 in the presence of hypophosphorous acid and sodium nitrite. Treatment of compound 4 with ethyl bromoacetate produced ethyl[3-(4-chloroph ...