Yayıncı "Elsevier" Biyomühendislik Bölümü Koleksiyonu için listeleme
Toplam kayıt 7, listelenen: 1-7
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Design, synthesis and biological evaluation of novel bischalcone derivatives as potential anticancer agents
(Elsevier, 2021)Building on our previous work that discovered chalcone as a promising pharmacophore for anticancer activity, we have various other chalcone derivatives and have synthesized a series of novel bischalcone to explore their ... -
Discovery of 5-(or 6)-benzoxazoles and oxazolo[4,5-b]pyridines as novel candidate antitumor agents targeting hTopo II alpha
(Elsevier, 2021)Discovery of novel anticancer drugs which have low toxicity and high activity is very significant area in anticancer drug research and development. One of the important targets for cancer treatment research is topoisomerase ... -
Molecular modeling strategies of cancer multidrug resistance
(Elsevier, 2021)Cancer remains a leading cause of morbidity and mortality worldwide. Hence, the increase in cancer cases observed in the elderly population, as well as in children and adolescents, makes human malignancies a prime target ... -
MoS2/Chitosan/GOx-Gelatin modified graphite surface: Preparation, characterization and its use for glucose determination
(Elsevier, 2021)Graphene-like new generation of two dimensional (2D) nanomaterials, in particular the family of transition metal dichalcogenides (TMDCs) have been attracting a wide range of research interest. Among the family of TMDCs, ... -
Syntheses, crystal structures, hirshfeld surface analyses and electrochemical etoposide/camptotechin sensor applications of acetaldehyde oxime derivatives
(Elsevier, 2022)(E)-2-(4-Hydroxyphenyl)-2-oxoacetaldehyde oxime monohydrate (I) and (E)-2-(4 Nitropheny1)-2oxoacetaldehyde oximes (II) were synthesized from 4'-hydroxyacetophenone and 4'-nitroacetophenone, respectively. Their structures ... -
Synthesis, biological activities, antioxidant properties, and molecular docking studies of novel bis-schiff base podands as responsive chemosensors for anions
(Elsevier, 2022)In this study, bis-carbonyl podand (triethylene glycol bis(2-carbonylphenyl)ether) ( 1 ) was synthesized from the reaction of triethylene glycol dichloride with salicylaldehyde. Then, Schiff base podans ( 2 and 3 ) were ... -
Synthesis, molecular docking and some metabolic enzyme inhibition properties of biphenyl-substituted chalcone derivatives
(Elsevier, 2022)The new synthesized biphenyl-substituted chalcone derivatives were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes. ...